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440 related items for PubMed ID: 11792566

  • 1. Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: the role of protein geranylgeranylation in the action of nitrogen-containing bisphosphonates on osteoclast precursors.
    Van Beek ER, Löwik CW, Papapoulos SE.
    Bone; 2002 Jan; 30(1):64-70. PubMed ID: 11792566
    [Abstract] [Full Text] [Related]

  • 2. The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates.
    van beek E, Löwik C, van der Pluijm G, Papapoulos S.
    J Bone Miner Res; 1999 May; 14(5):722-9. PubMed ID: 10320520
    [Abstract] [Full Text] [Related]

  • 3. Differentiating the mechanisms of antiresorptive action of nitrogen containing bisphosphonates.
    van Beek ER, Cohen LH, Leroy IM, Ebetino FH, Löwik CW, Papapoulos SE.
    Bone; 2003 Nov; 33(5):805-11. PubMed ID: 14623056
    [Abstract] [Full Text] [Related]

  • 4. Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.
    Coxon FP, Helfrich MH, Van't Hof R, Sebti S, Ralston SH, Hamilton A, Rogers MJ.
    J Bone Miner Res; 2000 Aug; 15(8):1467-76. PubMed ID: 10934645
    [Abstract] [Full Text] [Related]

  • 5. Bisphosphonates: the first 40 years.
    Russell RG.
    Bone; 2011 Jul; 49(1):2-19. PubMed ID: 21555003
    [Abstract] [Full Text] [Related]

  • 6. Effect of alendronate treatment on the osteoclastogenic potential of bone marrow cells in mice.
    van Beek ER, Löwik CW, Papapoulos SE.
    Bone; 1997 Apr; 20(4):335-40. PubMed ID: 9108353
    [Abstract] [Full Text] [Related]

  • 7. Effects of two novel bisphosphonates on bone cells in vitro.
    Evans CE, Braidman IP.
    Bone Miner; 1994 Aug; 26(2):95-107. PubMed ID: 7994190
    [Abstract] [Full Text] [Related]

  • 8. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.
    Luckman SP, Hughes DE, Coxon FP, Graham R, Russell G, Rogers MJ.
    J Bone Miner Res; 1998 Apr; 13(4):581-9. PubMed ID: 9556058
    [Abstract] [Full Text] [Related]

  • 9. In vitro and ex vivo evidence that estrogens suppress increased bone resorption induced by ovariectomy or PTH stimulation through an effect on osteoclastogenesis.
    Most W, Schot L, Ederveen A, van der Wee-Pals L, Papapoulos S, Löwik C.
    J Bone Miner Res; 1995 Oct; 10(10):1523-30. PubMed ID: 8686508
    [Abstract] [Full Text] [Related]

  • 10. Bisphosphonates induce osteoblasts to secrete an inhibitor of osteoclast-mediated resorption.
    Vitté C, Fleisch H, Guenther HL.
    Endocrinology; 1996 Jun; 137(6):2324-33. PubMed ID: 8641182
    [Abstract] [Full Text] [Related]

  • 11. New insights into the molecular mechanisms of action of bisphosphonates.
    Rogers MJ.
    Curr Pharm Des; 2003 Jun; 9(32):2643-58. PubMed ID: 14529538
    [Abstract] [Full Text] [Related]

  • 12. Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro.
    Idris AI, Rojas J, Greig IR, Van't Hof RJ, Ralston SH.
    Calcif Tissue Int; 2008 Mar; 82(3):191-201. PubMed ID: 18259679
    [Abstract] [Full Text] [Related]

  • 13. Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro.
    Benford HL, McGowan NW, Helfrich MH, Nuttall ME, Rogers MJ.
    Bone; 2001 May; 28(5):465-73. PubMed ID: 11344045
    [Abstract] [Full Text] [Related]

  • 14. Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption.
    Michael H, Härkönen PL, Väänänen HK, Hentunen TA.
    J Bone Miner Res; 2005 Dec; 20(12):2224-32. PubMed ID: 16294275
    [Abstract] [Full Text] [Related]

  • 15. Independent pathways in the modulation of osteoclastic resorption by intermediates of the mevalonate biosynthetic pathway: the role of the retinoic acid receptor.
    van Beek E, Löwik C, Karperien M, Papapoulos S.
    Bone; 2006 Feb; 38(2):167-71. PubMed ID: 16165408
    [Abstract] [Full Text] [Related]

  • 16. Leukemia inhibitory factor inhibits osteoclastic resorption, growth, mineralization, and alkaline phosphatase activity in fetal mouse metacarpal bones in culture.
    Van Beek E, Van der Wee-Pals L, van de Ruit M, Nijweide P, Papapoulos S, Löwik C.
    J Bone Miner Res; 1993 Feb; 8(2):191-8. PubMed ID: 8442437
    [Abstract] [Full Text] [Related]

  • 17. Two modes of action of bisphosphonates on osteoclastic resorption of mineralized matrix.
    Boonekamp PM, van der Wee-Pals LJ, van Wijk-van Lennep MM, Thesing CW, Bijvoet OL.
    Bone Miner; 1986 Feb; 1(1):27-39. PubMed ID: 3508715
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates.
    Dunford JE, Thompson K, Coxon FP, Luckman SP, Hahn FM, Poulter CD, Ebetino FH, Rogers MJ.
    J Pharmacol Exp Ther; 2001 Feb; 296(2):235-42. PubMed ID: 11160603
    [Abstract] [Full Text] [Related]

  • 19. Effects of bisphosphonates on osteoclastogenesis in RAW264.7 cells.
    Abe K, Yoshimura Y, Deyama Y, Kikuiri T, Hasegawa T, Tei K, Shinoda H, Suzuki K, Kitagawa Y.
    Int J Mol Med; 2012 Jun; 29(6):1007-15. PubMed ID: 22447156
    [Abstract] [Full Text] [Related]

  • 20. Integrins and osteoclastic resorption in three bone organ cultures: differential sensitivity to synthetic Arg-Gly-Asp peptides during osteoclast formation.
    van der Pluijm G, Mouthaan H, Baas C, de Groot H, Papapoulos S, Löwik C.
    J Bone Miner Res; 1994 Jul; 9(7):1021-8. PubMed ID: 7942148
    [Abstract] [Full Text] [Related]

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