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Journal Abstract Search
927 related items for PubMed ID: 11795592
1. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing. Mole DR, Maxwell PH, Pugh CW, Ratcliffe PJ. IUBMB Life; 2001 Jul; 52(1-2):43-7. PubMed ID: 11795592 [Abstract] [Full Text] [Related]
2. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. Nature; 1999 May 20; 399(6733):271-5. PubMed ID: 10353251 [Abstract] [Full Text] [Related]
3. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH. J Biol Chem; 2000 Aug 18; 275(33):25733-41. PubMed ID: 10823831 [Abstract] [Full Text] [Related]
4. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ. Science; 2001 Apr 20; 292(5516):468-72. PubMed ID: 11292861 [Abstract] [Full Text] [Related]
5. The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Pugh CW, Ratcliffe PJ. Semin Cancer Biol; 2003 Feb 20; 13(1):83-9. PubMed ID: 12507560 [Abstract] [Full Text] [Related]
8. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases. Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, Jelkmann W, Jaakkola P, Metzen E. Biochem J; 2004 Aug 01; 381(Pt 3):761-7. PubMed ID: 15104534 [Abstract] [Full Text] [Related]
9. Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP. Sang N, Fang J, Srinivas V, Leshchinsky I, Caro J. Mol Cell Biol; 2002 May 01; 22(9):2984-92. PubMed ID: 11940656 [Abstract] [Full Text] [Related]
10. HIF hydroxylation and the mammalian oxygen-sensing pathway. Safran M, Kaelin WG. J Clin Invest; 2003 Mar 01; 111(6):779-83. PubMed ID: 12639980 [No Abstract] [Full Text] [Related]
11. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. EMBO J; 2001 Sep 17; 20(18):5197-206. PubMed ID: 11566883 [Abstract] [Full Text] [Related]
12. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH. Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720 [Abstract] [Full Text] [Related]
18. Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress. Salnikow K, Donald SP, Bruick RK, Zhitkovich A, Phang JM, Kasprzak KS. J Biol Chem; 2004 Sep 24; 279(39):40337-44. PubMed ID: 15271983 [Abstract] [Full Text] [Related]