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Journal Abstract Search

167 related items for PubMed ID: 11806714

  • 1. Design, synthesis, and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure-activity investigation of metalloenzyme inhibition by iron chelators.
    Liu ZD, Kayyali R, Hider RC, Porter JB, Theobald AE.
    J Med Chem; 2002 Jan 31; 45(3):631-9. PubMed ID: 11806714
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  • 2. Structure-function investigation of the interaction of 1- and 2-substituted 3-hydroxypyridin-4-ones with 5-lipoxygenase and ribonucleotide reductase.
    Kayyali R, Porter JB, Liu ZD, Davies NA, Nugent JH, Cooper CE, Hider RC.
    J Biol Chem; 2001 Dec 28; 276(52):48814-22. PubMed ID: 11602611
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  • 3. Structure-activity investigation of the inhibition of 3-hydroxypyridin-4-ones on mammalian tyrosine hydroxylase.
    Liu ZD, Lockwood M, Rose S, Theobald AE, Hider RC.
    Biochem Pharmacol; 2001 Feb 01; 61(3):285-90. PubMed ID: 11172732
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  • 4. Synthesis, physicochemical characterization, and biological evaluation of 2-(1'-hydroxyalkyl)-3-hydroxypyridin-4-ones: novel iron chelators with enhanced pFe(3+) values.
    Liu ZD, Khodr HH, Liu DY, Lu SL, Hider RC.
    J Med Chem; 1999 Nov 18; 42(23):4814-23. PubMed ID: 10579844
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  • 5. Synthesis of 2-amido-3-hydroxypyridin-4(1H)-ones: novel iron chelators with enhanced pFe3+ values.
    Liu ZD, Piyamongkol S, Liu DY, Khodr HH, Lu SL, Hider RC.
    Bioorg Med Chem; 2001 Mar 18; 9(3):563-73. PubMed ID: 11310590
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  • 6. Synthesis, physicochemical properties, and evaluation of N-substituted-2-alkyl-3-hydroxy-4(1H)-pyridinones.
    Rai BL, Dekhordi LS, Khodr H, Jin Y, Liu Z, Hider RC.
    J Med Chem; 1998 Aug 27; 41(18):3347-59. PubMed ID: 9719587
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  • 7. Basic 3-hydroxypyridin-4-ones: potential antimalarial agents.
    Dehkordi LS, Liu ZD, Hider RC.
    Eur J Med Chem; 2008 May 27; 43(5):1035-47. PubMed ID: 17869385
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  • 9. Design, synthesis and evaluation of N-basic substituted 3-hydroxypyridin-4-ones: orally active iron chelators with lysosomotrophic potential.
    Liu ZD, Khodr HH, Lu SL, Hider RC.
    J Pharm Pharmacol; 2000 Mar 27; 52(3):263-72. PubMed ID: 10757413
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  • 15. Iron binding dendrimers: a novel approach for the treatment of haemochromatosis.
    Zhou T, Neubert H, Liu DY, Liu ZD, Ma YM, Kong XL, Luo W, Mark S, Hider RC.
    J Med Chem; 2006 Jul 13; 49(14):4171-82. PubMed ID: 16821777
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  • 17. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA, Abdellatif KR, Dong Y, Das D, Suresh MR, Knaus EE.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6138-41. PubMed ID: 18945614
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  • 19. Synthesis, physicochemical properties and biological evaluation of aromatic ester prodrugs of 1-(2'-hydroxyethyl)-2-ethyl-3-hydroxypyridin-4-one (CP102): orally active iron chelators with clinical potential.
    Liu ZD, Liu DY, Lu SL, Hider RC.
    J Pharm Pharmacol; 1999 May 01; 51(5):555-64. PubMed ID: 10411215
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