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Journal Abstract Search

167 related items for PubMed ID: 11806714

  • 21. Synthesis, iron binding and antimicrobial properties of hexadentate 3-hydroxypyridinones-terminated dendrimers.
    Zhou T, Chen K, Kong LM, Liu MS, Ma YM, Xie YY, Hider RC.
    Bioorg Med Chem Lett; 2018 Aug 01; 28(14):2504-2512. PubMed ID: 29886020
    [Abstract] [Full Text] [Related]

  • 22. Hydrolytic and metabolic characteristics of the esters of 1-(3'-hydroxypropyl)-2-methyl-3-hydroxypyridin-4-one (CP41), potentially useful iron chelators.
    Liu DY, Liu ZD, Lu SL, Hider RC.
    Pharmacol Toxicol; 2000 May 01; 86(5):228-33. PubMed ID: 10862505
    [Abstract] [Full Text] [Related]

  • 23. Synthesis and biological evaluation of 1-(benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene regioisomers: a novel class of 5-lipoxygenase inhibitors.
    Chowdhury MA, Chen H, Abdellatif KR, Dong Y, Petruk KC, Knaus EE.
    Bioorg Med Chem Lett; 2008 Jul 15; 18(14):4195-8. PubMed ID: 18541424
    [Abstract] [Full Text] [Related]

  • 24. DIBI, a novel 3-hydroxypyridin-4-one chelator iron-binding polymer, inhibits breast cancer cell growth and functions as a chemosensitizer by promoting S-phase DNA damage.
    Greenshields AL, Power Coombs MR, Fernando W, Holbein BE, Hoskin DW.
    Biometals; 2019 Dec 15; 32(6):909-921. PubMed ID: 31624972
    [Abstract] [Full Text] [Related]

  • 25. Phenyl substituted 3-hydroxypyridin-2(1H)-ones: inhibitors of influenza A endonuclease.
    Parhi AK, Xiang A, Bauman JD, Patel D, Vijayan RS, Das K, Arnold E, Lavoie EJ.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6435-46. PubMed ID: 24055080
    [Abstract] [Full Text] [Related]

  • 26. Inhibition of iron toxicity in rat and human hepatocyte cultures by the hydroxypyridin-4-ones CP20 and CP94.
    Chenoufi N, Hubert N, Loréal O, Morel I, Pasdeloup N, Cillard J, Brissot P, Lescoat G.
    J Hepatol; 1995 Aug 01; 23(2):166-73. PubMed ID: 7499788
    [Abstract] [Full Text] [Related]

  • 27. Iron chelators inhibit human platelet aggregation, thromboxane A2 synthesis and lipoxygenase activity.
    Barradas MA, Jeremy JY, Kontoghiorghes GJ, Mikhailidis DP, Hoffbrand AV, Dandona P.
    FEBS Lett; 1989 Mar 13; 245(1-2):105-9. PubMed ID: 2494068
    [Abstract] [Full Text] [Related]

  • 28. Design, synthesis, and biological evaluation of aromatic ester prodrugs of 1-(3'-hydroxypropyl)-2-methyl-3-hydroxypyridin-4-one (CP41) as orally active iron chelators.
    Liu ZD, Liu DY, Lu SL, Hider RC.
    Arzneimittelforschung; 2000 May 13; 50(5):461-70. PubMed ID: 10858874
    [Abstract] [Full Text] [Related]

  • 29.
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  • 30. The development of hydroxypyridin-4-ones as orally active iron chelators.
    Hider RC, Singh S, Porter JB, Huehns ER.
    Ann N Y Acad Sci; 1990 May 13; 612():327-38. PubMed ID: 2291561
    [No Abstract] [Full Text] [Related]

  • 31. Synthesis, physical-chemical characterisation and biological evaluation of novel 2-amido-3-hydroxypyridin-4(1H)-ones: Iron chelators with the potential for treating Alzheimer's disease.
    Gaeta A, Molina-Holgado F, Kong XL, Salvage S, Fakih S, Francis PT, Williams RJ, Hider RC.
    Bioorg Med Chem; 2011 Feb 01; 19(3):1285-97. PubMed ID: 21236688
    [Abstract] [Full Text] [Related]

  • 32. Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains.
    Zhou YJ, Liu MS, Osamah AR, Kong XL, Alsam S, Battah S, Xie YY, Hider RC, Zhou T.
    Eur J Med Chem; 2015 Apr 13; 94():8-21. PubMed ID: 25747496
    [Abstract] [Full Text] [Related]

  • 33. High affinity iron(III) scavenging by a novel hexadentate 3-hydroxypyridin-4-one-based dendrimer: synthesis and characterization.
    Zhou T, Liu ZD, Neubert H, Kong XL, Ma YM, Hider RC.
    Bioorg Med Chem Lett; 2005 Nov 15; 15(22):5007-11. PubMed ID: 16153843
    [Abstract] [Full Text] [Related]

  • 34. Aryl and Arylalkyl Substituted 3-Hydroxypyridin-2(1H)-ones: Synthesis and Evaluation as Inhibitors of Influenza A Endonuclease.
    Sagong HY, Bauman JD, Nogales A, Martínez-Sobrido L, Arnold E, LaVoie EJ.
    ChemMedChem; 2019 Jun 18; 14(12):1204-1223. PubMed ID: 30983160
    [Abstract] [Full Text] [Related]

  • 35. Synthesis and in-vitro antimicrobial evaluation of a high-affinity iron chelator in combination with chloramphenicol.
    Zhu CF, Qiu DH, Kong XL, Hider RC, Zhou T.
    J Pharm Pharmacol; 2013 Apr 18; 65(4):512-20. PubMed ID: 23488779
    [Abstract] [Full Text] [Related]

  • 36. Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells.
    Chua AC, Ingram HA, Raymond KN, Baker E.
    Eur J Biochem; 2003 Apr 18; 270(8):1689-98. PubMed ID: 12694182
    [Abstract] [Full Text] [Related]

  • 37. Characterisation of a novel oral iron chelator: 1-(N-Acetyl-6-Aminohexyl)-3-Hydroxy-2-Methylpyridin-4-one.
    Pangjit K, Banjerdpongchai R, Phisalaphong C, Fucharoen S, Xie YY, Lu ZD, Hider RC, Srichairatanakool S.
    J Pharm Pharmacol; 2015 May 18; 67(5):703-13. PubMed ID: 25627251
    [Abstract] [Full Text] [Related]

  • 38. The environment of the lipoxygenase iron binding site explored with novel hydroxypyridinone iron chelators.
    Abeysinghe RD, Roberts PJ, Cooper CE, MacLean KH, Hider RC, Porter JB.
    J Biol Chem; 1996 Apr 05; 271(14):7965-72. PubMed ID: 8626476
    [Abstract] [Full Text] [Related]

  • 39. Copper complexation by 3-hydroxypyridin-4-one iron chelators: structural and iron competition studies.
    el-Jammal A, Howell PL, Turner MA, Li N, Templeton DM.
    J Med Chem; 1994 Feb 18; 37(4):461-6. PubMed ID: 7509878
    [Abstract] [Full Text] [Related]

  • 40. Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators.
    Workman DG, Tsatsanis A, Lewis FW, Boyle JP, Mousadoust M, Hettiarachchi NT, Hunter M, Peers CS, Tétard D, Duce JA.
    Metallomics; 2015 May 18; 7(5):867-76. PubMed ID: 25781076
    [Abstract] [Full Text] [Related]

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