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Journal Abstract Search
171 related items for PubMed ID: 11809695
1. Farnesyltransferase inhibitors reverse Ras-mediated inhibition of Fas gene expression. Zhang B, Prendergast GC, Fenton RG. Cancer Res; 2002 Jan 15; 62(2):450-8. PubMed ID: 11809695 [Abstract] [Full Text] [Related]
2. Inhibition of Fas (CD95) expression and Fas-mediated apoptosis by oncogenic Ras. Fenton RG, Hixon JA, Wright PW, Brooks AD, Sayers TJ. Cancer Res; 1998 Aug 01; 58(15):3391-400. PubMed ID: 9699671 [Abstract] [Full Text] [Related]
3. Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1. DuHadaway JB, Du W, Donover S, Baker J, Liu AX, Sharp DM, Muller AJ, Prendergast GC. Oncogene; 2003 Jun 05; 22(23):3578-88. PubMed ID: 12789266 [Abstract] [Full Text] [Related]
4. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models. Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE. Cancer Res; 2001 Dec 15; 61(24):8758-68. PubMed ID: 11751396 [Abstract] [Full Text] [Related]
5. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines. Lerner EC, Zhang TT, Knowles DB, Qian Y, Hamilton AD, Sebti SM. Oncogene; 1997 Sep 15; 15(11):1283-8. PubMed ID: 9315095 [Abstract] [Full Text] [Related]
6. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2. Alcock RA, Dey S, Chendil D, Inayat MS, Mohiuddin M, Hartman G, Chatfield LK, Gallicchio VS, Ahmed MM. Oncogene; 2002 Nov 07; 21(51):7883-90. PubMed ID: 12420225 [Abstract] [Full Text] [Related]
7. p53 promotes selection for Fas-mediated apoptotic resistance. Maecker HL, Koumenis C, Giaccia AJ. Cancer Res; 2000 Aug 15; 60(16):4638-44. PubMed ID: 10969818 [Abstract] [Full Text] [Related]
8. Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts. Sun J, Qian Y, Hamilton AD, Sebti SM. Oncogene; 1998 Mar 15; 16(11):1467-73. PubMed ID: 9525745 [Abstract] [Full Text] [Related]
9. Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells. Park H, Lee YJ, Kim TH, Lee J, Yoon S, Choi WS, Myung CS, Kim HS. Int J Mol Med; 2008 Nov 15; 22(5):605-11. PubMed ID: 18949380 [Abstract] [Full Text] [Related]
12. The farnesyltransferase inhibitor, LB42708, inhibits growth and induces apoptosis irreversibly in H-ras and K-ras-transformed rat intestinal epithelial cells. Kim HS, Kim JW, Gang J, Wen J, Koh SS, Koh JS, Chung HH, Song SY. Toxicol Appl Pharmacol; 2006 Sep 15; 215(3):317-29. PubMed ID: 16712893 [Abstract] [Full Text] [Related]
13. Geranylgeranylated RhoB mediates suppression of human tumor cell growth by farnesyltransferase inhibitors. Du W, Prendergast GC. Cancer Res; 1999 Nov 01; 59(21):5492-6. PubMed ID: 10554025 [Abstract] [Full Text] [Related]
14. Induction of N-myc in neuroblastoma by autocrine IGF-II depends on farnesylated Ras. Application of farnesyltransferase inhibitors. Wittrock J, Schweizer P, Girgert R. Anticancer Res; 2002 Nov 01; 22(6C):4205-9. PubMed ID: 12553057 [Abstract] [Full Text] [Related]
17. Enhancement of tumor response by farnesyltransferase inhibitor in C3H/HeJ hepatocarcinoma. Kim J, Seong J, Kim SH. Ann N Y Acad Sci; 2004 Dec 01; 1030():95-102. PubMed ID: 15659785 [Abstract] [Full Text] [Related]