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227 related items for PubMed ID: 11814696

  • 1. Identification, tissue expression and chromosomal localization of human Obscurin-MLCK, a member of the titin and Dbl families of myosin light chain kinases.
    Russell MW, Raeker MO, Korytkowski KA, Sonneman KJ.
    Gene; 2002 Jan 09; 282(1-2):237-46. PubMed ID: 11814696
    [Abstract] [Full Text] [Related]

  • 2. Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.
    Sutter SB, Raeker MO, Borisov AB, Russell MW.
    Dev Genes Evol; 2004 Jul 09; 214(7):352-9. PubMed ID: 15185077
    [Abstract] [Full Text] [Related]

  • 3. Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth.
    Borisov AB, Raeker MO, Kontrogianni-Konstantopoulos A, Yang K, Kurnit DM, Bloch RJ, Russell MW.
    Biochem Biophys Res Commun; 2003 Oct 24; 310(3):910-8. PubMed ID: 14550291
    [Abstract] [Full Text] [Related]

  • 4. Drosophila stretchin-MLCK is a novel member of the Titin/Myosin light chain kinase family.
    Champagne MB, Edwards KA, Erickson HP, Kiehart DP.
    J Mol Biol; 2000 Jul 21; 300(4):759-77. PubMed ID: 10891286
    [Abstract] [Full Text] [Related]

  • 5. Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly.
    Young P, Ehler E, Gautel M.
    J Cell Biol; 2001 Jul 09; 154(1):123-36. PubMed ID: 11448995
    [Abstract] [Full Text] [Related]

  • 6. Complete human gene structure of obscurin: implications for isoform generation by differential splicing.
    Fukuzawa A, Idowu S, Gautel M.
    J Muscle Res Cell Motil; 2005 Jul 09; 26(6-8):427-34. PubMed ID: 16625316
    [Abstract] [Full Text] [Related]

  • 7. The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.
    Ford-Speelman DL, Roche JA, Bowman AL, Bloch RJ.
    Mol Biol Cell; 2009 Sep 09; 20(17):3905-17. PubMed ID: 19605563
    [Abstract] [Full Text] [Related]

  • 8. Three new isoforms of Caenorhabditis elegans UNC-89 containing MLCK-like protein kinase domains.
    Small TM, Gernert KM, Flaherty DB, Mercer KB, Borodovsky M, Benian GM.
    J Mol Biol; 2004 Sep 03; 342(1):91-108. PubMed ID: 15313609
    [Abstract] [Full Text] [Related]

  • 9. Obscurin is required for the lateral alignment of striated myofibrils in zebrafish.
    Raeker MO, Su F, Geisler SB, Borisov AB, Kontrogianni-Konstantopoulos A, Lyons SE, Russell MW.
    Dev Dyn; 2006 Aug 03; 235(8):2018-29. PubMed ID: 16779859
    [Abstract] [Full Text] [Related]

  • 10. The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.
    Debant A, Serra-Pagès C, Seipel K, O'Brien S, Tang M, Park SH, Streuli M.
    Proc Natl Acad Sci U S A; 1996 May 28; 93(11):5466-71. PubMed ID: 8643598
    [Abstract] [Full Text] [Related]

  • 11. Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue.
    Pasteris NG, Nagata K, Hall A, Gorski JL.
    Gene; 2000 Jan 25; 242(1-2):237-47. PubMed ID: 10721717
    [Abstract] [Full Text] [Related]

  • 12. The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9.
    Bowman AL, Catino DH, Strong JC, Randall WR, Kontrogianni-Konstantopoulos A, Bloch RJ.
    Mol Biol Cell; 2008 Sep 25; 19(9):3782-92. PubMed ID: 18579686
    [Abstract] [Full Text] [Related]

  • 13. Developmental expression and differential cellular localization of obscurin and obscurin-associated kinase in cardiac muscle cells.
    Borisov AB, Raeker MO, Russell MW.
    J Cell Biochem; 2008 Apr 01; 103(5):1621-35. PubMed ID: 18041765
    [Abstract] [Full Text] [Related]

  • 14. Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.
    Bagnato P, Barone V, Giacomello E, Rossi D, Sorrentino V.
    J Cell Biol; 2003 Jan 20; 160(2):245-53. PubMed ID: 12527750
    [Abstract] [Full Text] [Related]

  • 15. Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues.
    Pasteris NG, Gorski JL.
    Genomics; 1999 Aug 15; 60(1):57-66. PubMed ID: 10458911
    [Abstract] [Full Text] [Related]

  • 16. Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulum.
    Armani A, Galli S, Giacomello E, Bagnato P, Barone V, Rossi D, Sorrentino V.
    Exp Cell Res; 2006 Nov 01; 312(18):3546-58. PubMed ID: 16962094
    [Abstract] [Full Text] [Related]

  • 17. Molecular cloning, sequence and expression pattern analysis of the mouse orthologue of the leukemia-associated guanine nucleotide exchange factor.
    Zinovyeva M, Sveshnikova E, Visser J, Belyavsky A.
    Gene; 2004 Aug 04; 337():181-8. PubMed ID: 15276214
    [Abstract] [Full Text] [Related]

  • 18. The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system.
    Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S.
    Circ Res; 2001 Nov 23; 89(11):1065-72. PubMed ID: 11717165
    [Abstract] [Full Text] [Related]

  • 19. A single human myosin light chain kinase gene (MLCK; MYLK).
    Lazar V, Garcia JG.
    Genomics; 1999 Apr 15; 57(2):256-67. PubMed ID: 10198165
    [Abstract] [Full Text] [Related]

  • 20. Structural analysis of obscurin gene in hypertrophic cardiomyopathy.
    Arimura T, Matsumoto Y, Okazaki O, Hayashi T, Takahashi M, Inagaki N, Hinohara K, Ashizawa N, Yano K, Kimura A.
    Biochem Biophys Res Commun; 2007 Oct 19; 362(2):281-7. PubMed ID: 17716621
    [Abstract] [Full Text] [Related]

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