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854 related items for PubMed ID: 11818550

  • 1. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).
    Howland DS, Liu J, She Y, Goad B, Maragakis NJ, Kim B, Erickson J, Kulik J, DeVito L, Psaltis G, DeGennaro LJ, Cleveland DW, Rothstein JD.
    Proc Natl Acad Sci U S A; 2002 Feb 05; 99(3):1604-9. PubMed ID: 11818550
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  • 2. Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis.
    Dunlop J, Beal McIlvain H, She Y, Howland DS.
    J Neurosci; 2003 Mar 01; 23(5):1688-96. PubMed ID: 12629173
    [Abstract] [Full Text] [Related]

  • 3. Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice.
    Guo H, Lai L, Butchbach ME, Stockinger MP, Shan X, Bishop GA, Lin CL.
    Hum Mol Genet; 2003 Oct 01; 12(19):2519-32. PubMed ID: 12915461
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  • 4. GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.
    Li K, Hala TJ, Seetharam S, Poulsen DJ, Wright MC, Lepore AC.
    Neurobiol Dis; 2015 Jun 01; 78():12-23. PubMed ID: 25818008
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  • 5. Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.
    Peviani M, Salvaneschi E, Bontempi L, Petese A, Manzo A, Rossi D, Salmona M, Collina S, Bigini P, Curti D.
    Neurobiol Dis; 2014 Feb 01; 62():218-32. PubMed ID: 24141020
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  • 6. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.
    Lepore AC, Rauck B, Dejea C, Pardo AC, Rao MS, Rothstein JD, Maragakis NJ.
    Nat Neurosci; 2008 Nov 01; 11(11):1294-301. PubMed ID: 18931666
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  • 7. Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation.
    Han Y, Ripley B, Serada S, Naka T, Fujimoto M.
    PLoS One; 2016 Nov 01; 11(4):e0153399. PubMed ID: 27070121
    [Abstract] [Full Text] [Related]

  • 8. The Overexpression of TDP-43 Protein in the Neuron and Oligodendrocyte Cells Causes the Progressive Motor Neuron Degeneration in the SOD1 G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.
    Lu Y, Tang C, Zhu L, Li J, Liang H, Zhang J, Xu R.
    Int J Biol Sci; 2016 Nov 01; 12(9):1140-9. PubMed ID: 27570488
    [Abstract] [Full Text] [Related]

  • 9. In vivo quantification of spinal and bulbar motor neuron degeneration in the G93A-SOD1 transgenic mouse model of ALS by T2 relaxation time and apparent diffusion coefficient.
    Niessen HG, Angenstein F, Sander K, Kunz WS, Teuchert M, Ludolph AC, Heinze HJ, Scheich H, Vielhaber S.
    Exp Neurol; 2006 Oct 01; 201(2):293-300. PubMed ID: 16740261
    [Abstract] [Full Text] [Related]

  • 10. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC.
    Neurobiol Dis; 2000 Dec 01; 7(6 Pt B):623-43. PubMed ID: 11114261
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  • 12. A caspase-3-cleaved fragment of the glial glutamate transporter EAAT2 is sumoylated and targeted to promyelocytic leukemia nuclear bodies in mutant SOD1-linked amyotrophic lateral sclerosis.
    Gibb SL, Boston-Howes W, Lavina ZS, Gustincich S, Brown RH, Pasinelli P, Trotti D.
    J Biol Chem; 2007 Nov 02; 282(44):32480-90. PubMed ID: 17823119
    [Abstract] [Full Text] [Related]

  • 13. Motor neuron disease in transgenic mice with an H46R mutant SOD1 gene.
    Sasaki S, Nagai M, Aoki M, Komori T, Itoyama Y, Iwata M.
    J Neuropathol Exp Neurol; 2007 Jun 02; 66(6):517-24. PubMed ID: 17549011
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  • 14. Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice.
    Hossaini M, Cardona Cano S, van Dis V, Haasdijk ED, Hoogenraad CC, Holstege JC, Jaarsma D.
    J Neuropathol Exp Neurol; 2011 Aug 02; 70(8):662-77. PubMed ID: 21760539
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  • 17. Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1(G93A) mice.
    Pardo AC, Wong V, Benson LM, Dykes M, Tanaka K, Rothstein JD, Maragakis NJ.
    Exp Neurol; 2006 Sep 02; 201(1):120-30. PubMed ID: 16753145
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  • 18. Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS.
    Rosenblum LT, Shamamandri-Markandaiah S, Ghosh B, Foran E, Lepore AC, Pasinelli P, Trotti D.
    Exp Neurol; 2017 Jun 02; 292():145-153. PubMed ID: 28342750
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  • 19. Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.
    Thomsen GM, Gowing G, Latter J, Chen M, Vit JP, Staggenborg K, Avalos P, Alkaslasi M, Ferraiuolo L, Likhite S, Kaspar BK, Svendsen CN.
    J Neurosci; 2014 Nov 19; 34(47):15587-600. PubMed ID: 25411487
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