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Journal Abstract Search

215 related items for PubMed ID: 11830759

  • 1. SB-236057-A: a selective 5-HT1B receptor inverse agonist.
    Roberts C, Watson J, Price GW, Middlemiss DN.
    CNS Drug Rev; 2001; 7(4):433-44. PubMed ID: 11830759
    [Abstract] [Full Text] [Related]

  • 2. The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pig.
    Roberts C, Hatcher P, Hagan JJ, Austin NE, Jeffrey P, Wyman P, Gaster LM, Routledge C, Middlemiss DN.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Aug; 362(2):177-83. PubMed ID: 10961381
    [Abstract] [Full Text] [Related]

  • 3. SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
    Scott C, Soffin EM, Hill M, Atkinson PJ, Langmead CJ, Wren PB, Faedo S, Gordon LJ, Price GW, Bromidge S, Johnson CN, Hagan JJ, Watson J.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):54-61. PubMed ID: 16571351
    [Abstract] [Full Text] [Related]

  • 4. SB-236057, a selective 5-HT1B receptor inverse agonist, blocks the 5-HT human terminal autoreceptor.
    Middlemiss DN, Göthert M, Schlicker E, Scott CM, Selkirk JV, Watson J, Gaster LM, Wyman P, Riley G, Price GW.
    Eur J Pharmacol; 1999 Jun 30; 375(1-3):359-65. PubMed ID: 10443589
    [Abstract] [Full Text] [Related]

  • 5. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade.
    Roberts C, Boyd DF, Middlemiss DN, Routledge C.
    Neuropharmacology; 1999 Sep 30; 38(9):1409-19. PubMed ID: 10471095
    [Abstract] [Full Text] [Related]

  • 6. SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain.
    Thomas DR, Soffin EM, Roberts C, Kew JN, de la Flor RM, Dawson LA, Fry VA, Coggon SA, Faedo S, Hayes PD, Corbett DF, Davies CH, Hagan JJ.
    Neuropharmacology; 2006 Sep 30; 51(3):566-77. PubMed ID: 16846620
    [Abstract] [Full Text] [Related]

  • 7. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Gaster LM, Blaney FE, Davies S, Duckworth DM, Ham P, Jenkins S, Jennings AJ, Joiner GF, King FD, Mulholland KR, Wyman PA, Hagan JJ, Hatcher J, Jones BJ, Middlemiss DN, Price GW, Riley G, Roberts C, Routledge C, Selkirk J, Slade PD.
    J Med Chem; 1998 Apr 09; 41(8):1218-35. PubMed ID: 9548813
    [Abstract] [Full Text] [Related]

  • 8. SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue.
    Watson J, Roberts C, Scott C, Kendall I, Collin L, Day NC, Harries MH, Soffin E, Davies CH, Randall AD, Heightman T, Gaster L, Wyman P, Parker C, Price GW, Middlemiss DN.
    Br J Pharmacol; 2001 Jul 09; 133(6):797-806. PubMed ID: 11454652
    [Abstract] [Full Text] [Related]

  • 9. Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors.
    Schlicker E, Fink K, Molderings GJ, Price GW, Duckworth M, Gaster L, Middlemiss DN, Zentner J, Likungu J, Göthert M.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep 09; 356(3):321-7. PubMed ID: 9303568
    [Abstract] [Full Text] [Related]

  • 10. Importance of h5-HT1B receptor selectivity for 5-HT terminal autoreceptor activity: an in vivo microdialysis study in the freely-moving guinea-pig.
    Roberts C, Price GW, Gaster L, Jones BJ, Middlemiss DN, Routledge C.
    Neuropharmacology; 1997 Sep 09; 36(4-5):549-57. PubMed ID: 9225280
    [Abstract] [Full Text] [Related]

  • 11. SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
    Selkirk JV, Scott C, Ho M, Burton MJ, Watson J, Gaster LM, Collin L, Jones BJ, Middlemiss DN, Price GW.
    Br J Pharmacol; 1998 Sep 09; 125(1):202-8. PubMed ID: 9776361
    [Abstract] [Full Text] [Related]

  • 12. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig.
    Pullar IA, Boot JR, Broadmore RJ, Eyre TA, Cooper J, Sanger GJ, Wedley S, Mitchell SN.
    Eur J Pharmacol; 2004 Jun 16; 493(1-3):85-93. PubMed ID: 15189767
    [Abstract] [Full Text] [Related]

  • 13. Effect of a selective 5-HT reuptake inhibitor in combination with 5-HT1A and 5-HT1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo.
    Sharp T, Umbers V, Gartside SE.
    Br J Pharmacol; 1997 Jul 16; 121(5):941-6. PubMed ID: 9222551
    [Abstract] [Full Text] [Related]

  • 14. Effect of chronic paroxetine treatment on 5-HT1B and 5-HT1D autoreceptors in rat dorsal raphe nucleus.
    Davidson C, Stamford JA.
    Neurochem Int; 2000 Feb 16; 36(2):91-6. PubMed ID: 10676872
    [Abstract] [Full Text] [Related]

  • 15. Differential effects of 5-HT1B/1D receptor antagonists in dorsal and median raphe innervated brain regions.
    Roberts C, Belenguer A, Middlemiss DN, Routledge C.
    Eur J Pharmacol; 1998 Apr 10; 346(2-3):175-80. PubMed ID: 9652357
    [Abstract] [Full Text] [Related]

  • 16. Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.
    Hagan JJ, Slade PD, Gaster L, Jeffrey P, Hatcher JP, Middlemiss DN.
    Eur J Pharmacol; 1997 Jul 23; 331(2-3):169-74. PubMed ID: 9274976
    [Abstract] [Full Text] [Related]

  • 17. Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
    Bühlen M, Fink K, Böing C, Göthert M.
    Naunyn Schmiedebergs Arch Pharmacol; 1996 Feb 23; 353(3):281-9. PubMed ID: 8692282
    [Abstract] [Full Text] [Related]

  • 18. LY393558, a 5-hydroxytryptamine reuptake inhibitor and 5-HT(1B/1D) receptor antagonist: effects on extracellular levels of 5-hydroxytryptamine in the guinea pig and rat.
    Mitchell SN, Greenslade RG, Cooper J.
    Eur J Pharmacol; 2001 Nov 30; 432(1):19-27. PubMed ID: 11734183
    [Abstract] [Full Text] [Related]

  • 19. Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.
    Rollema H, Clarke T, Sprouse JS, Schulz DW.
    J Neurochem; 1996 Nov 30; 67(5):2204-7. PubMed ID: 8863532
    [Abstract] [Full Text] [Related]

  • 20. SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.
    Scott C, Langmead CJ, Clarke KL, Wyman P, Smith PW, Starr KR, Dawson LA, Price GW, Hagan JJ, Watson J.
    Neuropharmacology; 2006 Jun 30; 50(8):984-90. PubMed ID: 16546225
    [Abstract] [Full Text] [Related]

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