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Journal Abstract Search

217 related items for PubMed ID: 11831896

  • 1. Structural basis of RasGRP binding to high-affinity PKC ligands.
    Rong SB, Enyedy IJ, Qiao L, Zhao L, Ma D, Pearce LL, Lorenzo PS, Stone JC, Blumberg PM, Wang S, Kozikowski AP.
    J Med Chem; 2002 Feb 14; 45(4):853-60. PubMed ID: 11831896
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  • 2. Indolactam and benzolactam compounds as new medicinal leads with binding selectivity for C1 domains of protein kinase C isozymes.
    Irie K, Nakagawa Y, Ohigashi H.
    Curr Pharm Des; 2004 Feb 14; 10(12):1371-85. PubMed ID: 15134488
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  • 3. Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.
    Pak Y, Enyedy IJ, Varady J, Kung JW, Lorenzo PS, Blumberg PM, Wang S.
    J Med Chem; 2001 May 24; 44(11):1690-701. PubMed ID: 11356104
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  • 4. Iridals are a novel class of ligands for phorbol ester receptors with modest selectivity for the RasGRP receptor subfamily.
    Shao L, Lewin NE, Lorenzo PS, Hu Z, Enyedy IJ, Garfield SH, Stone JC, Marner FJ, Blumberg PM, Wang S.
    J Med Chem; 2001 Nov 08; 44(23):3872-80. PubMed ID: 11689073
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  • 5. Differential selectivity of ligands for the C1a and C1b phorbol ester binding domains of protein kinase Cdelta: possible correlation with tumor-promoting activity.
    Bögi K, Lorenzo PS, Szállási Z, Acs P, Wagner GS, Blumberg PM.
    Cancer Res; 1998 Apr 01; 58(7):1423-8. PubMed ID: 9537243
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  • 11. Modeling studies on the structural determinants for the DAG/phorbol ester binding to C1 domain.
    Rahman GM, Das J.
    J Biomol Struct Dyn; 2015 Apr 01; 33(1):219-32. PubMed ID: 24666138
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  • 12. Tumor promoter binding of the protein kinase C C1 homology domain peptides of RasGRPs, chimaerins, and Unc13s.
    Irie K, Masuda A, Shindo M, Nakagawa Y, Ohigashi H.
    Bioorg Med Chem; 2004 Sep 01; 12(17):4575-83. PubMed ID: 15358285
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  • 13. Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs.
    Johnson JE, Goulding RE, Ding Z, Partovi A, Anthony KV, Beaulieu N, Tazmini G, Cornell RB, Kay RJ.
    Biochem J; 2007 Sep 01; 406(2):223-36. PubMed ID: 17523924
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  • 16. Indolactam-V is involved in the CH/pi interaction with Pro-11 of the PKCdelta C1B domain: application for the structural optimization of the PKCdelta ligand.
    Nakagawa Y, Irie K, Yanagita RC, Ohigashi H, Tsuda K.
    J Am Chem Soc; 2005 Apr 27; 127(16):5746-7. PubMed ID: 15839646
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  • 18. A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha.
    Pu Y, Perry NA, Yang D, Lewin NE, Kedei N, Braun DC, Choi SH, Blumberg PM, Garfield SH, Stone JC, Duan D, Marquez VE.
    J Biol Chem; 2005 Jul 22; 280(29):27329-38. PubMed ID: 15923197
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