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Journal Abstract Search

175 related items for PubMed ID: 11857076

  • 1. Astrocyte-specific expression of CDK4 is not sufficient for tumor formation, but cooperates with p53 heterozygosity to provide a growth advantage for astrocytes in vivo.
    Huang ZY, Baldwin RL, Hedrick NM, Gutmann DH.
    Oncogene; 2002 Feb 21; 21(9):1325-34. PubMed ID: 11857076
    [Abstract] [Full Text] [Related]

  • 2. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.
    Ding H, Roncari L, Shannon P, Wu X, Lau N, Karaskova J, Gutmann DH, Squire JA, Nagy A, Guha A.
    Cancer Res; 2001 May 01; 61(9):3826-36. PubMed ID: 11325859
    [Abstract] [Full Text] [Related]

  • 3. Reduced latency but no increased brain tumor penetrance in mice with astrocyte specific expression of a human p53 mutant.
    Klein MA, Rüedi D, Nozaki M, Dell EW, Diserens AC, Seelentag W, Janzer RC, Aguzzi A, Hegi ME.
    Oncogene; 2000 Nov 09; 19(47):5329-37. PubMed ID: 11103934
    [Abstract] [Full Text] [Related]

  • 4. Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.
    Ding H, Shannon P, Lau N, Wu X, Roncari L, Baldwin RL, Takebayashi H, Nagy A, Gutmann DH, Guha A.
    Cancer Res; 2003 Mar 01; 63(5):1106-13. PubMed ID: 12615729
    [Abstract] [Full Text] [Related]

  • 5. Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A.
    Fuxe J, Akusjärvi G, Goike HM, Roos G, Collins VP, Pettersson RF.
    Cell Growth Differ; 2000 Jul 01; 11(7):373-84. PubMed ID: 10939591
    [Abstract] [Full Text] [Related]

  • 6. Lack of p16INK4 or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines.
    He J, Olson JJ, James CD.
    Cancer Res; 1995 Nov 01; 55(21):4833-6. PubMed ID: 7585516
    [Abstract] [Full Text] [Related]

  • 7. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma.
    Sonoda Y, Ozawa T, Hirose Y, Aldape KD, McMahon M, Berger MS, Pieper RO.
    Cancer Res; 2001 Jul 01; 61(13):4956-60. PubMed ID: 11431323
    [Abstract] [Full Text] [Related]

  • 8. Malignant transformation of p53-deficient astrocytes is modulated by environmental cues in vitro.
    Bögler O, Nagane M, Gillis J, Huang HJ, Cavenee WK.
    Cell Growth Differ; 1999 Feb 01; 10(2):73-86. PubMed ID: 10074901
    [Abstract] [Full Text] [Related]

  • 9. Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes.
    Holland EC, Hively WP, Gallo V, Varmus HE.
    Genes Dev; 1998 Dec 01; 12(23):3644-9. PubMed ID: 9851971
    [Abstract] [Full Text] [Related]

  • 10. Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes.
    Ericson KK, Krull D, Slomiany P, Grossel MJ.
    Mol Cancer Res; 2003 Jul 01; 1(9):654-64. PubMed ID: 12861051
    [Abstract] [Full Text] [Related]

  • 11. Growth inhibitory effect on glioma cells of adenovirus-mediated p16/INK4a gene transfer in vitro and in vivo.
    Lee SH, Kim MS, Kwon HC, Park IC, Park MJ, Lee CT, Kim YW, Kim CM, Hong SI.
    Int J Mol Med; 2000 Nov 01; 6(5):559-63. PubMed ID: 11029524
    [Abstract] [Full Text] [Related]

  • 12. Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras.
    Tremain R, Marko M, Kinnimulki V, Ueno H, Bottinger E, Glick A.
    Oncogene; 2000 Mar 23; 19(13):1698-709. PubMed ID: 10763827
    [Abstract] [Full Text] [Related]

  • 13. Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells.
    Uhlmann EJ, Apicelli AJ, Baldwin RL, Burke SP, Bajenaru ML, Onda H, Kwiatkowski D, Gutmann DH.
    Oncogene; 2002 Jun 06; 21(25):4050-9. PubMed ID: 12037687
    [Abstract] [Full Text] [Related]

  • 14. Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma.
    Dasgupta B, Yi Y, Hegedus B, Weber JD, Gutmann DH.
    Cancer Res; 2005 Nov 01; 65(21):9843-50. PubMed ID: 16267007
    [Abstract] [Full Text] [Related]

  • 15. Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression?
    Hlobilkova A, Ehrmann J, Sedlakova E, Krejci V, Knizetova P, Fiuraskova M, Kala M, Kalita O, Kolar Z.
    Neoplasma; 2007 Nov 01; 54(4):334-41. PubMed ID: 17822324
    [Abstract] [Full Text] [Related]

  • 16. Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice.
    Weissenberger J, Steinbach JP, Malin G, Spada S, Rülicke T, Aguzzi A.
    Oncogene; 1997 May 01; 14(17):2005-13. PubMed ID: 9160879
    [Abstract] [Full Text] [Related]

  • 17. Sequential extension of proliferative lifespan in human fibroblasts induced by over-expression of CDK4 or 6 and loss of p53 function.
    Morris M, Hepburn P, Wynford-Thomas D.
    Oncogene; 2002 Jun 20; 21(27):4277-88. PubMed ID: 12082615
    [Abstract] [Full Text] [Related]

  • 18. Correlation of histology and molecular genetic analysis of 1p, 19q, 10q, TP53, EGFR, CDK4, and CDKN2A in 91 astrocytic and oligodendroglial tumors.
    Ueki K, Nishikawa R, Nakazato Y, Hirose T, Hirato J, Funada N, Fujimaki T, Hojo S, Kubo O, Ide T, Usui M, Ochiai C, Ito S, Takahashi H, Mukasa A, Asai A, Kirino T.
    Clin Cancer Res; 2002 Jan 20; 8(1):196-201. PubMed ID: 11801559
    [Abstract] [Full Text] [Related]

  • 19. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice.
    Holland EC, Hively WP, DePinho RA, Varmus HE.
    Genes Dev; 1998 Dec 01; 12(23):3675-85. PubMed ID: 9851974
    [Abstract] [Full Text] [Related]

  • 20. No complementation between TP53 or RB-1 and v-src in astrocytomas of GFAP-v-src transgenic mice.
    Maddalena AS, Hainfellner JA, Hegi ME, Glatzel M, Aguzzi A.
    Brain Pathol; 1999 Oct 01; 9(4):627-37. PubMed ID: 10517501
    [Abstract] [Full Text] [Related]

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