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Journal Abstract Search

242 related items for PubMed ID: 11865669

  • 1. Structural insights into the promiscuity and function of the human pregnane X receptor.
    Watkins RE, Noble SM, Redinbo MR.
    Curr Opin Drug Discov Devel; 2002 Jan; 5(1):150-8. PubMed ID: 11865669
    [Abstract] [Full Text] [Related]

  • 2. The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity.
    Watkins RE, Wisely GB, Moore LB, Collins JL, Lambert MH, Williams SP, Willson TM, Kliewer SA, Redinbo MR.
    Science; 2001 Jun 22; 292(5525):2329-33. PubMed ID: 11408620
    [Abstract] [Full Text] [Related]

  • 3. Pregnane X receptor: promiscuous regulator of detoxification pathways.
    Matic M, Mahns A, Tsoli M, Corradin A, Polly P, Robertson GR.
    Int J Biochem Cell Biol; 2007 Jun 22; 39(3):478-83. PubMed ID: 17188925
    [Abstract] [Full Text] [Related]

  • 4. Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.
    Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT.
    Mol Endocrinol; 2002 May 22; 16(5):977-86. PubMed ID: 11981033
    [Abstract] [Full Text] [Related]

  • 5. Identification of amino acids in rat pregnane X receptor that determine species-specific activation.
    Tirona RG, Leake BF, Podust LM, Kim RB.
    Mol Pharmacol; 2004 Jan 22; 65(1):36-44. PubMed ID: 14722235
    [Abstract] [Full Text] [Related]

  • 6. Structural model reveals key interactions in the assembly of the pregnane X receptor/corepressor complex.
    Wang CY, Li CW, Chen JD, Welsh WJ.
    Mol Pharmacol; 2006 May 22; 69(5):1513-7. PubMed ID: 16452398
    [Abstract] [Full Text] [Related]

  • 7. Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development.
    Kamiya A, Inoue Y, Gonzalez FJ.
    Hepatology; 2003 Jun 22; 37(6):1375-84. PubMed ID: 12774017
    [Abstract] [Full Text] [Related]

  • 8. The nuclear xenobiotic receptor pregnane X receptor: recent insights and new challenges.
    Orans J, Teotico DG, Redinbo MR.
    Mol Endocrinol; 2005 Dec 22; 19(12):2891-900. PubMed ID: 15961506
    [Abstract] [Full Text] [Related]

  • 9. Structure and function of the human nuclear xenobiotic receptor PXR.
    Carnahan VE, Redinbo MR.
    Curr Drug Metab; 2005 Aug 22; 6(4):357-67. PubMed ID: 16101574
    [Abstract] [Full Text] [Related]

  • 10. Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects.
    di Masi A, De Marinis E, Ascenzi P, Marino M.
    Mol Aspects Med; 2009 Oct 22; 30(5):297-343. PubMed ID: 19427329
    [Abstract] [Full Text] [Related]

  • 11. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.
    Kliewer SA, Goodwin B, Willson TM.
    Endocr Rev; 2002 Oct 22; 23(5):687-702. PubMed ID: 12372848
    [Abstract] [Full Text] [Related]

  • 12. Regulation of hepatic drug metabolism: role of the nuclear receptors PXR and CAR.
    Liddle C, Goodwin B.
    Semin Liver Dis; 2002 Oct 22; 22(2):115-22. PubMed ID: 12016543
    [Abstract] [Full Text] [Related]

  • 13. Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin.
    Chrencik JE, Orans J, Moore LB, Xue Y, Peng L, Collins JL, Wisely GB, Lambert MH, Kliewer SA, Redinbo MR.
    Mol Endocrinol; 2005 May 22; 19(5):1125-34. PubMed ID: 15705662
    [Abstract] [Full Text] [Related]

  • 14. Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor alpha binding site within the proximal promoter of PXR.
    Aouabdi S, Gibson G, Plant N.
    Drug Metab Dispos; 2006 Jan 22; 34(1):138-44. PubMed ID: 16243957
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of in vitro PXR-based assays and in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR.
    Xiao L, Nickbarg E, Wang W, Thomas A, Ziebell M, Prosise WW, Lesburg CA, Taremi SS, Gerlach VL, Le HV, Cheng KC.
    Biochem Pharmacol; 2011 Mar 01; 81(5):669-79. PubMed ID: 21145880
    [Abstract] [Full Text] [Related]

  • 16. Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier.
    Bauer B, Hartz AM, Fricker G, Miller DS.
    Mol Pharmacol; 2004 Sep 01; 66(3):413-9. PubMed ID: 15322232
    [Abstract] [Full Text] [Related]

  • 17. Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X receptor (PXR).
    Echchgadda I, Song CS, Oh TS, Cho SH, Rivera OJ, Chatterjee B.
    Mech Ageing Dev; 2004 Sep 01; 125(10-11):733-45. PubMed ID: 15541768
    [Abstract] [Full Text] [Related]

  • 18. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
    Wagner M, Halilbasic E, Marschall HU, Zollner G, Fickert P, Langner C, Zatloukal K, Denk H, Trauner M.
    Hepatology; 2005 Aug 01; 42(2):420-30. PubMed ID: 15986414
    [Abstract] [Full Text] [Related]

  • 19. Pregnane X receptor-mediated transcription.
    Chang TK, Waxman DJ.
    Methods Enzymol; 2005 Aug 01; 400():588-98. PubMed ID: 16399372
    [Abstract] [Full Text] [Related]

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