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165 related items for PubMed ID: 11870881

  • 1. Role of glutathione conjugate efflux in cellular protection against benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage.
    Srivastava SK, Watkins SC, Schuetz E, Singh SV.
    Mol Carcinog; 2002 Mar; 33(3):156-62. PubMed ID: 11870881
    [Abstract] [Full Text] [Related]

  • 2. Metabolic fate of glutathione conjugate of benzo[a]pyrene-(7R,8S)-diol (9S,10R)-epoxide in human liver.
    Srivastava SK, Hu X, Xia H, Awasthi S, Amin S, Singh SV.
    Arch Biochem Biophys; 1999 Nov 15; 371(2):340-4. PubMed ID: 10545223
    [Abstract] [Full Text] [Related]

  • 3. ATP-dependent transport of glutathione conjugate of 7beta, 8alpha-dihydroxy-9alpha,10alpha-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene in murine hepatic canalicular plasma membrane vesicles.
    Srivastava SK, Hu X, Xia H, Bleicher RJ, Zaren HA, Orchard JL, Awasthi S, Singh SV.
    Biochem J; 1998 Jun 15; 332 ( Pt 3)(Pt 3):799-805. PubMed ID: 9620885
    [Abstract] [Full Text] [Related]

  • 4. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase.
    Hu X, Herzog C, Zimniak P, Singh SV.
    Cancer Res; 1999 May 15; 59(10):2358-62. PubMed ID: 10344744
    [Abstract] [Full Text] [Related]

  • 5. Glutathione conjugation and DNA adduct formation of dibenzo[a,l]pyrene and benzo[a]pyrene diol epoxides in V79 cells stably expressing different human glutathione transferases.
    Sundberg K, Dreij K, Seidel A, Jernström B.
    Chem Res Toxicol; 2002 Feb 15; 15(2):170-9. PubMed ID: 11849043
    [Abstract] [Full Text] [Related]

  • 6. Multidrug resistance-associated proteins are involved in the transport of the glutathione conjugates of the ultimate carcinogen of benzo[a]pyrene in human Caco-2 cells.
    Hessel S, John A, Seidel A, Lampen A.
    Arch Toxicol; 2013 Feb 15; 87(2):269-80. PubMed ID: 22899102
    [Abstract] [Full Text] [Related]

  • 7. Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT).
    Guo A, Marinaro W, Hu P, Sinko PJ.
    Drug Metab Dispos; 2002 Apr 15; 30(4):457-63. PubMed ID: 11901101
    [Abstract] [Full Text] [Related]

  • 8. Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide.
    Singh SV, Varma V, Zimniak P, Srivastava SK, Marynowski SW, Desai D, Amin S, Ji X.
    Biochemistry; 2004 Aug 03; 43(30):9708-15. PubMed ID: 15274625
    [Abstract] [Full Text] [Related]

  • 9. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X, O'Donnell R, Srivastava SK, Xia H, Zimniak P, Nanduri B, Bleicher RJ, Awasthi S, Awasthi YC, Ji X, Singh SV.
    Biochem Biophys Res Commun; 1997 Jun 18; 235(2):424-8. PubMed ID: 9199210
    [Abstract] [Full Text] [Related]

  • 10. Effects of microsomes and liposomes on glutathione transferase catalysed conjugation of benzo[a]pyrene diol epoxide with glutathione.
    Ooi SG, Jernström B, Ahokas J.
    Chem Biol Interact; 1994 Apr 18; 91(1):15-27. PubMed ID: 8194122
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of stably transfected human glutathione S-transferase P1-1 protects against DNA damage by benzo[a]pyrene diol-epoxide in human T47D cells.
    Fields WR, Morrow CS, Doss AJ, Sundberg K, Jernström B, Townsend AJ.
    Mol Pharmacol; 1998 Aug 18; 54(2):298-304. PubMed ID: 9687571
    [Abstract] [Full Text] [Related]

  • 12. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ.
    Carcinogenesis; 2007 Jan 18; 28(1):207-14. PubMed ID: 16885195
    [Abstract] [Full Text] [Related]

  • 13. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.
    Paulusma CC, van Geer MA, Evers R, Heijn M, Ottenhoff R, Borst P, Oude Elferink RP.
    Biochem J; 1999 Mar 01; 338 ( Pt 2)(Pt 2):393-401. PubMed ID: 10024515
    [Abstract] [Full Text] [Related]

  • 14. Detection of benzo(a)pyrene diol epoxide-DNA adducts in mononuclear white blood cells by CE immunoassay and its application to studying the effect of glutathione depletion.
    LeBlanc A, Shen S, Lew K, Weinfeld M, Le XC.
    Electrophoresis; 2009 May 01; 30(9):1558-63. PubMed ID: 19343725
    [Abstract] [Full Text] [Related]

  • 15. Comparison of the mRNA sequences for Pi class glutathione transferases in different hamster species and the corresponding enzyme activities with anti-benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide.
    Swedmark S, Jernström B, Jenssen D.
    Biochem J; 1996 Sep 01; 318 ( Pt 2)(Pt 2):533-8. PubMed ID: 8809043
    [Abstract] [Full Text] [Related]

  • 16. High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma.
    Rojas M, Marie B, Vignaud JM, Martinet N, Siat J, Grosdidier G, Cascorbi I, Alexandrov K.
    Cancer Lett; 2004 Apr 30; 207(2):157-63. PubMed ID: 15072824
    [Abstract] [Full Text] [Related]

  • 17. Cloning, expression, and biochemical characterization of a functionally novel alpha class glutathione S-transferase with exceptional activity in the glutathione conjugation of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Xia H, Pan SS, Hu X, Srivastava SK, Pal A, Singh SV.
    Arch Biochem Biophys; 1998 May 15; 353(2):337-48. PubMed ID: 9606968
    [Abstract] [Full Text] [Related]

  • 18. An alpha class mouse glutathione S-transferase with exceptional catalytic efficiency in the conjugation of glutathione with 7beta, 8alpha-dihydroxy-9alpha,10alpha-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X, Srivastava SK, Xia H, Awasthi YC, Singh SV.
    J Biol Chem; 1996 Dec 20; 271(51):32684-8. PubMed ID: 8955099
    [Abstract] [Full Text] [Related]

  • 19. DNA adduct formation in mouse tissues in relation to serum levels of benzo(a)pyrene-diol-epoxide after injection of benzo(a)pyrene or the diol-epoxide.
    Ginsberg GL, Atherholt TB.
    Cancer Res; 1990 Feb 15; 50(4):1189-94. PubMed ID: 2105163
    [Abstract] [Full Text] [Related]

  • 20. Enhancement of benzo[a]pyrene diol epoxide mutagenicity by sulfite in a mammalian test system.
    Reed GA, Jones BC.
    Carcinogenesis; 1996 May 15; 17(5):1063-8. PubMed ID: 8640914
    [Abstract] [Full Text] [Related]

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