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Journal Abstract Search

94 related items for PubMed ID: 11886804

  • 1.
    ; . PubMed ID:
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  • 2. Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes.
    Tamamura H, Omagari A, Oishi S, Kanamoto T, Yamamoto N, Peiper SC, Nakashima H, Otaka A, Fujii N.
    Bioorg Med Chem Lett; 2000 Dec 04; 10(23):2633-7. PubMed ID: 11128640
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety.
    Tamamura H, Hiramatsu K, Miyamoto K, Omagari A, Oishi S, Nakashima H, Yamamoto N, Kuroda Y, Nakagawa T, Otaka A, Fujii N.
    Bioorg Med Chem Lett; 2002 Mar 25; 12(6):923-8. PubMed ID: 11958995
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  • 4. Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140.
    Tamamura H, Omagari A, Hiramatsu K, Gotoh K, Kanamoto T, Xu Y, Kodama E, Matsuoka M, Hattori T, Yamamoto N, Nakashima H, Otaka A, Fujii N.
    Bioorg Med Chem Lett; 2001 Jul 23; 11(14):1897-902. PubMed ID: 11459656
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  • 5. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.
    Tamamura H, Hiramatsu K, Ueda S, Wang Z, Kusano S, Terakubo S, Trent JO, Peiper SC, Yamamoto N, Nakashima H, Otaka A, Fujii N.
    J Med Chem; 2005 Jan 27; 48(2):380-91. PubMed ID: 15658852
    [Abstract] [Full Text] [Related]

  • 6. Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity.
    Tamamura H, Sugioka M, Odagaki Y, Omagari A, Kan Y, Oishi S, Nakashima H, Yamamoto N, Peiper SC, Hamanaka N, Otaka A, Fujii N.
    Bioorg Med Chem Lett; 2001 Feb 12; 11(3):359-62. PubMed ID: 11212110
    [Abstract] [Full Text] [Related]

  • 7. A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140.
    Tamamura H, Xu Y, Hattori T, Zhang X, Arakaki R, Kanbara K, Omagari A, Otaka A, Ibuka T, Yamamoto N, Nakashima H, Fujii N.
    Biochem Biophys Res Commun; 1998 Dec 30; 253(3):877-82. PubMed ID: 9918823
    [Abstract] [Full Text] [Related]

  • 8. Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists.
    Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Navenot JM, Peiper SC, Fujii N.
    Bioconjug Chem; 2012 Jun 20; 23(6):1259-65. PubMed ID: 22486464
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives.
    Tamamura H, Hiramatsu K, Kusano aS, Terakubo S, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N.
    Org Biomol Chem; 2003 Nov 07; 1(21):3656-62. PubMed ID: 14649896
    [Abstract] [Full Text] [Related]

  • 10. [Development of selective antagonists against an HIV second receptor].
    Tamamura H.
    Yakugaku Zasshi; 2001 Nov 07; 121(11):781-92. PubMed ID: 11725546
    [Abstract] [Full Text] [Related]

  • 11. Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site.
    Boulais PE, Dulude D, Cabana J, Heveker N, Escher E, Lavigne P, Leduc R.
    Biochem Pharmacol; 2009 Dec 01; 78(11):1382-90. PubMed ID: 19631193
    [Abstract] [Full Text] [Related]

  • 12.
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  • 14. Pharmacophore identification of a chemokine receptor (CXCR4) antagonist, T22 ([Tyr(5,12),Lys7]-polyphemusin II), which specifically blocks T cell-line-tropic HIV-1 infection.
    Tamamura H, Imai M, Ishihara T, Masuda M, Funakoshi H, Oyake H, Murakami T, Arakaki R, Nakashima H, Otaka A, Ibuka T, Waki M, Matsumoto A, Yamamoto N, Fujii N.
    Bioorg Med Chem; 1998 Jul 01; 6(7):1033-41. PubMed ID: 9730240
    [Abstract] [Full Text] [Related]

  • 15. Dissociation of the signalling and antiviral properties of SDF-1-derived small peptides.
    Heveker N, Montes M, Germeroth L, Amara A, Trautmann A, Alizon M, Schneider-Mergener J.
    Curr Biol; 1998 Mar 26; 8(7):369-76. PubMed ID: 9545196
    [Abstract] [Full Text] [Related]

  • 16. Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.
    Tsutsumi H, Tanaka T, Ohashi N, Masuno H, Tamamura H, Hiramatsu K, Araki T, Ueda S, Oishi S, Fujii N.
    Biopolymers; 2007 Mar 26; 88(2):279-89. PubMed ID: 17167792
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4.
    Bridger GJ, Skerlj RT, Padmanabhan S, Martellucci SA, Henson GW, Struyf S, Witvrouw M, Schols D, De Clercq E.
    J Med Chem; 1999 Sep 23; 42(19):3971-81. PubMed ID: 10508445
    [Abstract] [Full Text] [Related]

  • 18. Structure-function study and anti-HIV activity of synthetic peptide analogues derived from viral chemokine vMIP-II.
    Luo Z, Fan X, Zhou N, Hiraoka M, Luo J, Kaji H, Huang Z.
    Biochemistry; 2000 Nov 07; 39(44):13545-50. PubMed ID: 11063591
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  • 19. A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection.
    Murakami T, Nakajima T, Koyanagi Y, Tachibana K, Fujii N, Tamamura H, Yoshida N, Waki M, Matsumoto A, Yoshie O, Kishimoto T, Yamamoto N, Nagasawa T.
    J Exp Med; 1997 Oct 20; 186(8):1389-93. PubMed ID: 9334379
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  • 20. Pharmacophore-based small molecule CXCR4 ligands.
    Narumi T, Tanaka T, Hashimoto C, Nomura W, Aikawa H, Sohma A, Itotani K, Kawamata M, Murakami T, Yamamoto N, Tamamura H.
    Bioorg Med Chem Lett; 2012 Jun 15; 22(12):4169-72. PubMed ID: 22579418
    [Abstract] [Full Text] [Related]

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