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Journal Abstract Search


110 related items for PubMed ID: 11888556

  • 1. Pharmacological profile of SB-357134: a potent, selective, brain penetrant, and orally active 5-HT(6) receptor antagonist.
    Stean TO, Hirst WD, Thomas DR, Price GW, Rogers D, Riley G, Bromidge SM, Serafinowska HT, Smith DR, Bartlett S, Deeks N, Duxon M, Upton N.
    Pharmacol Biochem Behav; 2002 Apr; 71(4):645-54. PubMed ID: 11888556
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  • 3. Characterization of SB-271046: a potent, selective and orally active 5-HT(6) receptor antagonist.
    Routledge C, Bromidge SM, Moss SF, Price GW, Hirst W, Newman H, Riley G, Gager T, Stean T, Upton N, Clarke SE, Brown AM, Middlemiss DN.
    Br J Pharmacol; 2000 Aug; 130(7):1606-12. PubMed ID: 10928964
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  • 6. Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities.
    Schaffhauser H, Mathiasen JR, Dicamillo A, Huffman MJ, Lu LD, McKenna BA, Qian J, Marino MJ.
    Biochem Pharmacol; 2009 Oct 15; 78(8):1035-42. PubMed ID: 19549510
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  • 7. SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats.
    Thomas DR, Melotto S, Massagrande M, Gribble AD, Jeffrey P, Stevens AJ, Deeks NJ, Eddershaw PJ, Fenwick SH, Riley G, Stean T, Scott CM, Hill MJ, Middlemiss DN, Hagan JJ, Price GW, Forbes IT.
    Br J Pharmacol; 2003 Jun 15; 139(4):705-14. PubMed ID: 12812993
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  • 8. Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.
    Hagan JJ, Price GW, Jeffrey P, Deeks NJ, Stean T, Piper D, Smith MI, Upton N, Medhurst AD, Middlemiss DN, Riley GJ, Lovell PJ, Bromidge SM, Thomas DR.
    Br J Pharmacol; 2000 Jun 15; 130(3):539-48. PubMed ID: 10821781
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  • 9. Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression.
    Wesołowska A, Nikiforuk A.
    Neuropharmacology; 2007 Apr 15; 52(5):1274-83. PubMed ID: 17320917
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  • 10. The effect of SB-269970, a 5-HT(7) receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies.
    Roberts C, Allen L, Langmead CJ, Hagan JJ, Middlemiss DN, Price GW.
    Br J Pharmacol; 2001 Apr 15; 132(7):1574-80. PubMed ID: 11264252
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  • 11. 5-HT6 receptor antagonists enhance retention of a water maze task in the rat.
    Rogers DC, Hagan JJ.
    Psychopharmacology (Berl); 2001 Nov 15; 158(2):114-9. PubMed ID: 11702084
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  • 12. New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.
    Liao Y, Böttcher H, Harting J, Greiner H, van Amsterdam C, Cremers T, Sundell S, März J, Rautenberg W, Wikström H.
    J Med Chem; 2000 Feb 10; 43(3):517-25. PubMed ID: 10669578
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  • 13. The 5-HT(6) receptor antagonist SB-271046 reverses scopolamine-disrupted consolidation of a passive avoidance task and ameliorates spatial task deficits in aged rats.
    Foley AG, Murphy KJ, Hirst WD, Gallagher HC, Hagan JJ, Upton N, Walsh FS, Regan CM.
    Neuropsychopharmacology; 2004 Jan 10; 29(1):93-100. PubMed ID: 14571256
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  • 14. Decreased agonist, but not antagonist, binding to the naturally occurring Thr92Lys variant of the h5-HT7(a) receptor.
    Brüss M, Kiel S, Bönisch H, Kostanian A, Göthert M.
    Neurochem Int; 2005 Aug 10; 47(3):196-203. PubMed ID: 15896881
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  • 15. Procognitive 5-HT6 antagonists in the rat forced swimming test: potential therapeutic utility in mood disorders associated with Alzheimer's disease.
    Hirano K, Piers TM, Searle KL, Miller ND, Rutter AR, Chapman PF.
    Life Sci; 2009 Apr 10; 84(15-16):558-62. PubMed ID: 19302808
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  • 16. The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585.
    Roberts JC, Reavill C, East SZ, Harrison PJ, Patel S, Routledge C, Leslie RA.
    Brain Res; 2002 Apr 26; 934(1):49-57. PubMed ID: 11937069
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  • 17. RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist.
    Hegde SS, Bonhaus DW, Johnson LG, Leung E, Clark RD, Eglen RM.
    Br J Pharmacol; 1995 Jul 26; 115(6):1087-95. PubMed ID: 7582507
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  • 18. Design, synthesis, and pharmacological evaluation of piperidin-4-yl amino aryl sulfonamides: novel, potent, selective, orally active, and brain penetrant 5-HT₆ receptor antagonists.
    Nirogi R, Shinde A, Daulatabad A, Kambhampati R, Gudla P, Shaik M, Gampa M, Balasubramaniam S, Gangadasari P, Reballi V, Badange R, Bojja K, Subramanian R, Bhyrapuneni G, Muddana N, Jayarajan P.
    J Med Chem; 2012 Nov 08; 55(21):9255-69. PubMed ID: 23006002
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  • 19. The selective 5-HT1A antagonist radioligand [3H]WAY 100635 labels both G-protein-coupled and free 5-HT1A receptors in rat brain membranes.
    Gozlan H, Thibault S, Laporte AM, Lima L, Hamon M.
    Eur J Pharmacol; 1995 Jan 16; 288(2):173-86. PubMed ID: 7720779
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  • 20. SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties.
    Moser PC, Bergis OE, Jegham S, Lochead A, Duconseille E, Terranova JP, Caille D, Berque-Bestel I, Lezoualc'h F, Fischmeister R, Dumuis A, Bockaert J, George P, Soubrié P, Scatton B.
    J Pharmacol Exp Ther; 2002 Aug 16; 302(2):731-41. PubMed ID: 12130738
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