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330 related items for PubMed ID: 11903050

  • 1. Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.
    Fang J, Hsu BY, MacMullen CM, Poncz M, Smith TJ, Stanley CA.
    Biochem J; 2002 Apr 01; 363(Pt 1):81-7. PubMed ID: 11903050
    [Abstract] [Full Text] [Related]

  • 2. Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.
    Plaitakis A, Metaxari M, Shashidharan P.
    J Neurochem; 2000 Nov 01; 75(5):1862-9. PubMed ID: 11032875
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  • 3. Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
    Smith TJ, Peterson PE, Schmidt T, Fang J, Stanley CA.
    J Mol Biol; 2001 Mar 23; 307(2):707-20. PubMed ID: 11254391
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  • 4. Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice.
    Li C, Matter A, Kelly A, Petty TJ, Najafi H, MacMullen C, Daikhin Y, Nissim I, Lazarow A, Kwagh J, Collins HW, Hsu BY, Nissim I, Yudkoff M, Matschinsky FM, Stanley CA.
    J Biol Chem; 2006 Jun 02; 281(22):15064-72. PubMed ID: 16574664
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  • 8. Molecular basis and characterization of the hyperinsulinism/hyperammonemia syndrome: predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene. HI/HA Contributing Investigators.
    Stanley CA, Fang J, Kutyna K, Hsu BY, Ming JE, Glaser B, Poncz M.
    Diabetes; 2000 Apr 02; 49(4):667-73. PubMed ID: 10871207
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  • 9. The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery.
    Peterson PE, Smith TJ.
    Structure; 1999 Jul 15; 7(7):769-82. PubMed ID: 10425679
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  • 10. Effects of ADP on different inhibitory properties of brain glutamate dehydrogenase isoproteins by perphenazine.
    Yoon HY, Hwang SH, Lee EY, Kim TU, Cho EH, Cho SW.
    Biochimie; 2001 Sep 15; 83(9):907-13. PubMed ID: 11698113
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  • 11. Regulation of glutamate metabolism and insulin secretion by glutamate dehydrogenase in hypoglycemic children.
    Stanley CA.
    Am J Clin Nutr; 2009 Sep 15; 90(3):862S-866S. PubMed ID: 19625687
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  • 12. Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase.
    Smith HQ, Smith TJ.
    Biochemistry; 2016 Nov 29; 55(47):6568-6576. PubMed ID: 27808506
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  • 13. Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.
    Zaganas I, Plaitakis A.
    J Biol Chem; 2002 Jul 19; 277(29):26422-8. PubMed ID: 11950837
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  • 14. Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase.
    MacMullen C, Fang J, Hsu BY, Kelly A, de Lonlay-Debeney P, Saudubray JM, Ganguly A, Smith TJ, Stanley CA, Hyperinsulinism/hyperammonemia Contributing Investigators.
    J Clin Endocrinol Metab; 2001 Apr 19; 86(4):1782-7. PubMed ID: 11297618
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  • 15. Glutaminolysis and insulin secretion: from bedside to bench and back.
    Kelly A, Li C, Gao Z, Stanley CA, Matschinsky FM.
    Diabetes; 2002 Dec 19; 51 Suppl 3():S421-6. PubMed ID: 12475785
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  • 16. Identification of the GTP binding site of human glutamate dehydrogenase by cassette mutagenesis and photoaffinity labeling.
    Lee EY, Yoon HY, Ahn JY, Choi SY, Cho SW.
    J Biol Chem; 2001 Dec 21; 276(51):47930-6. PubMed ID: 11600502
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  • 17. Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase.
    Aleshin VA, Bunik VI, Bruch EM, Bellinzoni M.
    Int J Mol Sci; 2022 Sep 25; 23(19):. PubMed ID: 36232607
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  • 18. Allosteric regulation of glutamate dehydrogenase deamination activity.
    Bera S, Rashid M, Medvinsky AB, Sun GQ, Li BL, Acquisti C, Sljoka A, Chakraborty A.
    Sci Rep; 2020 Oct 05; 10(1):16523. PubMed ID: 33020580
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  • 19. Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.
    Zaganas I, Spanaki C, Karpusas M, Plaitakis A.
    J Biol Chem; 2002 Nov 29; 277(48):46552-8. PubMed ID: 12324473
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  • 20. Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.
    Mastorodemos V, Zaganas I, Spanaki C, Bessa M, Plaitakis A.
    J Neurosci Res; 2002 Nov 29; 79(1-2):65-73. PubMed ID: 15578726
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