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753 related items for PubMed ID: 11916914

  • 1. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
    Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.
    Diabetes; 2002 Apr; 51(4):966-76. PubMed ID: 11916914
    [Abstract] [Full Text] [Related]

  • 2. Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).
    Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG, Rhodes CJ.
    J Biol Chem; 2001 Jun 15; 276(24):21110-20. PubMed ID: 11274216
    [Abstract] [Full Text] [Related]

  • 3. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
    Cousin SP, Hügl SR, Myers MG, White MF, Reifel-Miller A, Rhodes CJ.
    Biochem J; 1999 Dec 15; 344 Pt 3(Pt 3):649-58. PubMed ID: 10585851
    [Abstract] [Full Text] [Related]

  • 4. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C, Welsh M.
    Mol Med; 2002 Nov 15; 8(11):705-13. PubMed ID: 12520087
    [Abstract] [Full Text] [Related]

  • 5. Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1.
    Cousin SP, Hügl SR, Wrede CE, Kajio H, Myers MG, Rhodes CJ.
    Endocrinology; 2001 Jan 15; 142(1):229-40. PubMed ID: 11145586
    [Abstract] [Full Text] [Related]

  • 6. Stimulation of insulin-like growth factor (IGF) binding protein-3 synthesis by IGF-I and transforming growth factor-alpha is mediated by both phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways in mammary epithelial cells.
    Sivaprasad U, Fleming J, Verma PS, Hogan KA, Desury G, Cohick WS.
    Endocrinology; 2004 Sep 15; 145(9):4213-21. PubMed ID: 15192040
    [Abstract] [Full Text] [Related]

  • 7. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M, Morelli C, Mauro L, Andò S, Surmacz E.
    Cancer Res; 2001 Sep 15; 61(18):6747-54. PubMed ID: 11559546
    [Abstract] [Full Text] [Related]

  • 8. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.
    Kurihara S, Hakuno F, Takahashi S.
    Endocr J; 2000 Dec 15; 47(6):739-51. PubMed ID: 11228049
    [Abstract] [Full Text] [Related]

  • 9. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N, Makeeva N, Welsh M.
    Mol Med; 2002 Nov 15; 8(11):695-704. PubMed ID: 12520086
    [Abstract] [Full Text] [Related]

  • 10. Growth factor-specific regulation of insulin receptor substrate-1 expression in MCF-7 breast carcinoma cells: effects on the insulin-like growth factor signaling pathway.
    Lassarre C, Ricort JM.
    Endocrinology; 2003 Nov 15; 144(11):4811-9. PubMed ID: 12960057
    [Abstract] [Full Text] [Related]

  • 11. Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1).
    Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ.
    J Mol Endocrinol; 2003 Jun 15; 30(3):271-86. PubMed ID: 12790799
    [Abstract] [Full Text] [Related]

  • 12. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.
    Cancer Res; 2003 Jan 15; 63(2):364-74. PubMed ID: 12543789
    [Abstract] [Full Text] [Related]

  • 13. Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism.
    Miele C, Riboulet A, Maitan MA, Oriente F, Romano C, Formisano P, Giudicelli J, Beguinot F, Van Obberghen E.
    J Biol Chem; 2003 Nov 28; 278(48):47376-87. PubMed ID: 12970360
    [Abstract] [Full Text] [Related]

  • 14. Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
    Andreozzi F, Laratta E, Sciacqua A, Perticone F, Sesti G.
    Circ Res; 2004 May 14; 94(9):1211-8. PubMed ID: 15044323
    [Abstract] [Full Text] [Related]

  • 15. Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells.
    Hügl SR, White MF, Rhodes CJ.
    J Biol Chem; 1998 Jul 10; 273(28):17771-9. PubMed ID: 9651378
    [Abstract] [Full Text] [Related]

  • 16. Integrative mitogenic role of protein kinase B/Akt in beta-cells.
    Trümper K, Trümper A, Trusheim H, Arnold R, Göke B, Hörsch D.
    Ann N Y Acad Sci; 2000 Jul 10; 921():242-50. PubMed ID: 11193829
    [Abstract] [Full Text] [Related]

  • 17. Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling.
    Kim B, Cheng HL, Margolis B, Feldman EL.
    J Biol Chem; 1998 Dec 18; 273(51):34543-50. PubMed ID: 9852124
    [Abstract] [Full Text] [Related]

  • 18. IRS-1 tyrosine phosphorylation reflects insulin-induced metabolic and mitogenic responses in 3T3-L1 pre-adipocytes.
    Telting D, van der Zon GC, Dorrestijn J, Maassen JA.
    Arch Physiol Biochem; 2001 Feb 18; 109(1):52-62. PubMed ID: 11471071
    [Abstract] [Full Text] [Related]

  • 19. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O, Cantley LC.
    Exp Cell Res; 2004 Jul 01; 297(1):224-34. PubMed ID: 15194438
    [Abstract] [Full Text] [Related]

  • 20. Signalling pathways of insulin-like growth factor-I that are augmented by cAMP in FRTL-5 cells.
    Ariga M, Nedachi T, Akahori M, Sakamoto H, Ito Y, Hakuno F, Takahashi S.
    Biochem J; 2000 Jun 01; 348 Pt 2(Pt 2):409-16. PubMed ID: 10816436
    [Abstract] [Full Text] [Related]

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