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Journal Abstract Search

176 related items for PubMed ID: 11918801

  • 21. Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
    Scott AG, Tait A, Turner CM.
    Exp Parasitol; 1997 Jul; 86(3):181-90. PubMed ID: 9225768
    [Abstract] [Full Text] [Related]

  • 22. Arsenical-resistant trypanosomes lack an unusual adenosine transporter.
    Carter NS, Fairlamb AH.
    Nature; 1993 Jan 14; 361(6408):173-6. PubMed ID: 8421523
    [Abstract] [Full Text] [Related]

  • 23. Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei.
    Zimmermann S, Oufir M, Leroux A, Krauth-Siegel RL, Becker K, Kaiser M, Brun R, Hamburger M, Adams M.
    Bioorg Med Chem; 2013 Nov 15; 21(22):7202-9. PubMed ID: 24080104
    [Abstract] [Full Text] [Related]

  • 24. Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
    Matovu E, Stewart ML, Geiser F, Brun R, Mäser P, Wallace LJ, Burchmore RJ, Enyaru JC, Barrett MP, Kaminsky R, Seebeck T, de Koning HP.
    Eukaryot Cell; 2003 Oct 15; 2(5):1003-8. PubMed ID: 14555482
    [Abstract] [Full Text] [Related]

  • 25. Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods.
    Wyllie S, Oza SL, Patterson S, Spinks D, Thompson S, Fairlamb AH.
    Mol Microbiol; 2009 Nov 15; 74(3):529-40. PubMed ID: 19558432
    [Abstract] [Full Text] [Related]

  • 26. Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin.
    Scott AG, Tait A, Turner CM.
    Acta Trop; 1996 Feb 15; 60(4):251-62. PubMed ID: 8659324
    [Abstract] [Full Text] [Related]

  • 27. Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes.
    Baker N, Glover L, Munday JC, Aguinaga Andrés D, Barrett MP, de Koning HP, Horn D.
    Proc Natl Acad Sci U S A; 2012 Jul 03; 109(27):10996-1001. PubMed ID: 22711816
    [Abstract] [Full Text] [Related]

  • 28. A nucleoside transporter from Trypanosoma brucei involved in drug resistance.
    Mäser P, Sütterlin C, Kralli A, Kaminsky R.
    Science; 1999 Jul 09; 285(5425):242-4. PubMed ID: 10398598
    [Abstract] [Full Text] [Related]

  • 29. Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol.
    Graf FE, Ludin P, Wenzler T, Kaiser M, Brun R, Pyana PP, Büscher P, de Koning HP, Horn D, Mäser P.
    PLoS Negl Trop Dis; 2013 Jul 09; 7(10):e2475. PubMed ID: 24130910
    [Abstract] [Full Text] [Related]

  • 30. Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.
    Munday JC, Eze AA, Baker N, Glover L, Clucas C, Aguinaga Andrés D, Natto MJ, Teka IA, McDonald J, Lee RS, Graf FE, Ludin P, Burchmore RJ, Turner CM, Tait A, MacLeod A, Mäser P, Barrett MP, Horn D, De Koning HP.
    J Antimicrob Chemother; 2014 Mar 09; 69(3):651-63. PubMed ID: 24235095
    [Abstract] [Full Text] [Related]

  • 31. Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on trypanosoma brucei by forming an adduct with trypanothione.
    Alkhaldi AA, Creek DJ, Ibrahim H, Kim DH, Quashie NB, Burgess KE, Changtam C, Barrett MP, Suksamrarn A, de Koning HP.
    Mol Pharmacol; 2015 Mar 09; 87(3):451-64. PubMed ID: 25527638
    [Abstract] [Full Text] [Related]

  • 32. Effects of trypanocidal drugs on DNA synthesis: new insights into melarsoprol growth inhibition.
    Larson S, Carter M, Hovel-Miner G.
    Parasitology; 2021 Sep 09; 148(10):1143-1150. PubMed ID: 33593467
    [Abstract] [Full Text] [Related]

  • 33. Stress-Induced Protein S-Glutathionylation and S-Trypanothionylation in African Trypanosomes-A Quantitative Redox Proteome and Thiol Analysis.
    Ulrich K, Finkenzeller C, Merker S, Rojas F, Matthews K, Ruppert T, Krauth-Siegel RL.
    Antioxid Redox Signal; 2017 Sep 20; 27(9):517-533. PubMed ID: 28338335
    [Abstract] [Full Text] [Related]

  • 34. Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine.
    Steverding D, Rushworth SA.
    Exp Parasitol; 2017 Jul 20; 178():45-50. PubMed ID: 28552794
    [Abstract] [Full Text] [Related]

  • 35. Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters.
    Schumann Burkard G, Jutzi P, Roditi I.
    Mol Biochem Parasitol; 2011 Jan 20; 175(1):91-4. PubMed ID: 20851719
    [Abstract] [Full Text] [Related]

  • 36. Uptake and mode of action of drugs used against sleeping sickness.
    Denise H, Barrett MP.
    Biochem Pharmacol; 2001 Jan 01; 61(1):1-5. PubMed ID: 11137702
    [Abstract] [Full Text] [Related]

  • 37. In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei.
    Fairlamb AH, Henderson GB, Bacchi CJ, Cerami A.
    Mol Biochem Parasitol; 1987 Jun 01; 24(2):185-91. PubMed ID: 3114634
    [Abstract] [Full Text] [Related]

  • 38. Functional analysis of drug resistance-associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein.
    Munday JC, Tagoe DN, Eze AA, Krezdorn JA, Rojas López KE, Alkhaldi AA, McDonald F, Still J, Alzahrani KJ, Settimo L, De Koning HP.
    Mol Microbiol; 2015 May 01; 96(4):887-900. PubMed ID: 25708978
    [Abstract] [Full Text] [Related]

  • 39. Characterization of Trypanosoma brucei gamma-glutamylcysteine synthetase, an essential enzyme in the biosynthesis of trypanothione (diglutathionylspermidine).
    Lueder DV, Phillips MA.
    J Biol Chem; 1996 Jul 19; 271(29):17485-90. PubMed ID: 8663359
    [Abstract] [Full Text] [Related]

  • 40. Glyoxalase II does not support methylglyoxal detoxification but serves as a general trypanothione thioesterase in African trypanosomes.
    Wendler A, Irsch T, Rabbani N, Thornalley PJ, Krauth-Siegel RL.
    Mol Biochem Parasitol; 2009 Jan 19; 163(1):19-27. PubMed ID: 18848584
    [Abstract] [Full Text] [Related]

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