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Journal Abstract Search


138 related items for PubMed ID: 11941497

  • 1. A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464.
    McGregor TD, Hegmans A, Kaspárková J, Neplechová K, Nováková O, Penazová H, Vrána O, Brabec V, Farrell N.
    J Biol Inorg Chem; 2002 Apr; 7(4-5):397-404. PubMed ID: 11941497
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  • 2. DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent.
    Brabec V, Kaspárková J, Vrána O, Nováková O, Cox JW, Qu Y, Farrell N.
    Biochemistry; 1999 May 25; 38(21):6781-90. PubMed ID: 10346899
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  • 3. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A, Berners-Price SJ, Davies MS, Thomas DS, Humphreys AS, Farrell N.
    J Am Chem Soc; 2004 Feb 25; 126(7):2166-80. PubMed ID: 14971952
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  • 4. Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents.
    Kloster M, Kostrhunova H, Zaludova R, Malina J, Kasparkova J, Brabec V, Farrell N.
    Biochemistry; 2004 Jun 22; 43(24):7776-86. PubMed ID: 15196020
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  • 10. Amide-based prodrugs of spermidine-bridged dinuclear platinum. Synthesis, DNA binding, and biological activity.
    Hegmans A, Kasparkova J, Vrana O, Kelland LR, Brabec V, Farrell NP.
    J Med Chem; 2008 Apr 10; 51(7):2254-60. PubMed ID: 18338842
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  • 12. Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding.
    Kasparkova J, Vrana O, Farrell N, Brabec V.
    J Inorg Biochem; 2004 Oct 10; 98(10):1560-9. PubMed ID: 15458817
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  • 13. Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes.
    Qu Y, Scarsdale NJ, Tran MC, Farrell N.
    J Inorg Biochem; 2004 Oct 10; 98(10):1585-90. PubMed ID: 15458820
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  • 14. Consequences of nucleic acid conformation on the binding of a trinuclear platinum drug.
    Kloster MB, Hannis JC, Muddiman DC, Farrell N.
    Biochemistry; 1999 Nov 09; 38(45):14731-7. PubMed ID: 10555954
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