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Journal Abstract Search

227 related items for PubMed ID: 11944822

  • 1. Inhibitors of protein farnesyltransferase as novel anticancer agents.
    Ohkanda J, Knowles DB, Blaskovich MA, Sebti SM, Hamilton AD.
    Curr Top Med Chem; 2002 Mar; 2(3):303-23. PubMed ID: 11944822
    [Abstract] [Full Text] [Related]

  • 2. Inhibitors of farnesyltransferase and geranylgeranyltransferase-I for antitumor therapy: substrate-based design, conformational constraint and biological activity.
    Dinsmore CJ, Bell IM.
    Curr Top Med Chem; 2003 Mar; 3(10):1075-93. PubMed ID: 12769709
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  • 3. Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies.
    Sebti SM, Hamilton AD.
    Oncogene; 2000 Dec 27; 19(56):6584-93. PubMed ID: 11426643
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  • 4. Inhibition of Ras prenylation: a novel approach to cancer chemotherapy.
    Sebti SM, Hamilton AD.
    Pharmacol Ther; 1997 Dec 27; 74(1):103-14. PubMed ID: 9336018
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  • 5. Probing the hydrophobic pocket of farnesyltransferase: aromatic substitution of CAAX peptidomimetics leads to highly potent inhibitors.
    Qian Y, Marugan JJ, Fossum RD, Vogt A, Sebti SM, Hamilton AD.
    Bioorg Med Chem; 1999 Dec 27; 7(12):3011-24. PubMed ID: 10658608
    [Abstract] [Full Text] [Related]

  • 6. Farnesyltransferase inhibitors as anticancer agents: current status.
    Zhu K, Hamilton AD, Sebti SM.
    Curr Opin Investig Drugs; 2003 Dec 27; 4(12):1428-35. PubMed ID: 14763128
    [Abstract] [Full Text] [Related]

  • 7. Pseudodipeptide inhibitors of protein farnesyltransferase.
    deSolms SJ, Deana AA, Giuliani EA, Graham SL, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Scholz TH.
    J Med Chem; 1995 Sep 29; 38(20):3967-71. PubMed ID: 7562930
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  • 10. Farnesyltransferase inhibitors: potential role in the treatment of cancer.
    Cox AD.
    Drugs; 2001 Sep 29; 61(6):723-32. PubMed ID: 11398905
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  • 11. Protein farnesyltransferase inhibitors.
    Ayral-Kaloustian S, Salaski EJ.
    Curr Med Chem; 2002 May 29; 9(10):1003-32. PubMed ID: 12733981
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  • 13. Design, synthesis, and characterization of piperazinedione-based dual protein inhibitors for both farnesyltransferase and geranylgeranyltransferase-I.
    Qiao Y, Gao J, Qiu Y, Wu L, Guo F, Lo KK, Li D.
    Eur J Med Chem; 2011 Jun 29; 46(6):2264-73. PubMed ID: 21440964
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  • 17. Synthesis and evaluation of homofarnesoyl-substituted CAAX-peptidomimetics as farnesyltransferase inhibitors and antiproliferative agents.
    Schlitzer M, Sattler I, Dahse HM.
    Bioorg Med Chem; 1999 Sep 29; 7(9):2037-45. PubMed ID: 10530953
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