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324 related items for PubMed ID: 11945064

  • 1. Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro.
    Zielske SP, Gerson SL.
    Mol Ther; 2002 Apr; 5(4):381-7. PubMed ID: 11945064
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  • 2. In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.
    Zielske SP, Reese JS, Lingas KT, Donze JR, Gerson SL.
    J Clin Invest; 2003 Nov; 112(10):1561-70. PubMed ID: 14617757
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  • 3. Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Davis BM, Reese JS, Koç ON, Lee K, Schupp JE, Gerson SL.
    Cancer Res; 1997 Nov 15; 57(22):5093-9. PubMed ID: 9371508
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  • 4. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
    Ragg S, Xu-Welliver M, Bailey J, D'Souza M, Cooper R, Chandra S, Seshadri R, Pegg AE, Williams DA.
    Cancer Res; 2000 Sep 15; 60(18):5187-95. PubMed ID: 11016647
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  • 10. In vivo selection for human and murine hematopoietic cells transduced with a therapeutic MGMT lentiviral vector that inhibits HIV replication.
    Davis BM, Humeau L, Dropulic B.
    Mol Ther; 2004 Feb 15; 9(2):160-72. PubMed ID: 14759800
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  • 13. Protection of CHO cells by mutant forms of O6-alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O6-benzylguanine or O6-benzyl-8-oxoguanine.
    Loktionova NA, Xu-Welliver M, Crone TM, Kanugula S, Pegg AE.
    Biochem Pharmacol; 1999 Jul 15; 58(2):237-44. PubMed ID: 10423163
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  • 19. F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
    Maier P, Heckmann D, Spier I, Laufs S, Zucknick M, Allgayer H, Fruehauf S, Zeller WJ, Wenz F.
    Cancer Gene Ther; 2012 Nov 15; 19(11):802-10. PubMed ID: 23037811
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  • 20. Differential competitive resistance to methylating versus chloroethylating agents among five O6-alkylguanine DNA alkyltransferases in human hematopoietic cells.
    Fontes AM, Davis BM, Encell LP, Lingas K, Covas DT, Zago MA, Loeb LA, Pegg AE, Gerson SL.
    Mol Cancer Ther; 2006 Jan 15; 5(1):121-8. PubMed ID: 16432170
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