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Journal Abstract Search

289 related items for PubMed ID: 11950789

  • 1. Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.
    Ripp SL, Fitzpatrick JL, Peters JM, Prough RA.
    Drug Metab Dispos; 2002 May; 30(5):570-5. PubMed ID: 11950789
    [Abstract] [Full Text] [Related]

  • 2. Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor.
    Kohalmy K, Tamási V, Kóbori L, Sárváry E, Pascussi JM, Porrogi P, Rozman D, Prough RA, Meyer UA, Monostory K.
    Drug Metab Dispos; 2007 Sep; 35(9):1495-501. PubMed ID: 17591676
    [Abstract] [Full Text] [Related]

  • 3. Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate.
    Peters JM, Zhou YC, Ram PA, Lee SS, Gonzalez FJ, Waxman DJ.
    Mol Pharmacol; 1996 Jul; 50(1):67-74. PubMed ID: 8700121
    [Abstract] [Full Text] [Related]

  • 4. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.
    Nallani SC, Goodwin B, Maglich JM, Buckley DJ, Buckley AR, Desai PB.
    Drug Metab Dispos; 2003 May; 31(5):681-4. PubMed ID: 12695359
    [Abstract] [Full Text] [Related]

  • 5. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC, Das PC, Dekrey GK, Gardiner CS, Cao Y, Rose RL, Wallace AD.
    Toxicol Appl Pharmacol; 2010 Jun 15; 245(3):335-43. PubMed ID: 20361990
    [Abstract] [Full Text] [Related]

  • 6. Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.
    LeCluyse EL.
    Chem Biol Interact; 2001 May 16; 134(3):283-9. PubMed ID: 11336976
    [Abstract] [Full Text] [Related]

  • 7. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
    Teng S, Piquette-Miller M.
    J Pharmacol Exp Ther; 2005 Feb 16; 312(2):841-8. PubMed ID: 15456840
    [Abstract] [Full Text] [Related]

  • 8. CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.
    Shenoy SD, Spencer TA, Mercer-Haines NA, Alipour M, Gargano MD, Runge-Morris M, Kocarek TA.
    Drug Metab Dispos; 2004 Jan 16; 32(1):66-71. PubMed ID: 14709622
    [Abstract] [Full Text] [Related]

  • 9. Regulation of drug transporter gene expression by nuclear receptors.
    Staudinger JL, Madan A, Carol KM, Parkinson A.
    Drug Metab Dispos; 2003 May 16; 31(5):523-7. PubMed ID: 12695338
    [Abstract] [Full Text] [Related]

  • 10. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
    Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW.
    Pharmacogenomics J; 2004 May 16; 4(2):91-101. PubMed ID: 14770174
    [Abstract] [Full Text] [Related]

  • 11. Induction of microsomal and peroxisomal enzymes by dehydroepiandrosterone and its reduced metabolite in rats.
    Prough RA, Webb SJ, Wu HQ, Lapenson DP, Waxman DJ.
    Cancer Res; 1994 Jun 01; 54(11):2878-86. PubMed ID: 8187072
    [Abstract] [Full Text] [Related]

  • 12. Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta.
    Chen YH, Wang JP, Wang H, Sun MF, Wei LZ, Wei W, Xu DX.
    Toxicology; 2005 Aug 01; 211(3):242-52. PubMed ID: 15869837
    [Abstract] [Full Text] [Related]

  • 13. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.
    Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191
    [Abstract] [Full Text] [Related]

  • 14. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR, Sueyoshi T, Smith CM, Negishi M, Lecluyse EL, Wang H.
    J Pharmacol Exp Ther; 2006 Jun 01; 317(3):1200-9. PubMed ID: 16513849
    [Abstract] [Full Text] [Related]

  • 15. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
    Fisher CD, Jackson JP, Lickteig AJ, Augustine LM, Cherrington NJ.
    Arch Toxicol; 2008 Dec 01; 82(12):959-64. PubMed ID: 18488193
    [Abstract] [Full Text] [Related]

  • 16. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
    Wang H, Faucette SR, Gilbert D, Jolley SL, Sueyoshi T, Negishi M, LeCluyse EL.
    Drug Metab Dispos; 2003 May 01; 31(5):620-30. PubMed ID: 12695351
    [Abstract] [Full Text] [Related]

  • 17. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
    Cheng X, Klaassen CD.
    Toxicol Sci; 2008 Nov 01; 106(1):29-36. PubMed ID: 18648086
    [Abstract] [Full Text] [Related]

  • 18. Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor.
    Brobst DE, Ding X, Creech KL, Goodwin B, Kelley B, Staudinger JL.
    J Pharmacol Exp Ther; 2004 Aug 01; 310(2):528-35. PubMed ID: 15075359
    [Abstract] [Full Text] [Related]

  • 19. Perinatal lipopolysaccharide exposure downregulates pregnane X receptor and Cyp3a11 expression in fetal mouse liver.
    Xu DX, Chen YH, Wang JP, Sun MF, Wang H, Wei LZ, Wei W.
    Toxicol Sci; 2005 Sep 01; 87(1):38-45. PubMed ID: 15976188
    [Abstract] [Full Text] [Related]

  • 20. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P.
    Drug Metab Dispos; 2007 Jul 01; 35(7):1032-41. PubMed ID: 17392393
    [Abstract] [Full Text] [Related]

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