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Journal Abstract Search

289 related items for PubMed ID: 11950789

  • 21. Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone.
    Webb SJ, Xiao GH, Geoghegan TE, Prough RA.
    Mol Pharmacol; 1996 Feb; 49(2):276-87. PubMed ID: 8632760
    [Abstract] [Full Text] [Related]

  • 22. The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators.
    Pacyniak EK, Cheng X, Cunningham ML, Crofton K, Klaassen CD, Guo GL.
    Toxicol Sci; 2007 May; 97(1):94-102. PubMed ID: 17324954
    [Abstract] [Full Text] [Related]

  • 23. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
    Ohbuchi M, Yoshinari K, Kaneko H, Matsumoto S, Inoue A, Kawamura A, Usui T, Yamazoe Y.
    Antimicrob Agents Chemother; 2013 Mar; 57(3):1332-8. PubMed ID: 23274663
    [Abstract] [Full Text] [Related]

  • 24. The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
    Jones SA, Moore LB, Shenk JL, Wisely GB, Hamilton GA, McKee DD, Tomkinson NC, LeCluyse EL, Lambert MH, Willson TM, Kliewer SA, Moore JT.
    Mol Endocrinol; 2000 Jan; 14(1):27-39. PubMed ID: 10628745
    [Abstract] [Full Text] [Related]

  • 25. Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices.
    Cui X, Thomas A, Montgomery D, Gu C, Morrison RA, White RE, Cheng KC.
    Comb Chem High Throughput Screen; 2005 Jun; 8(4):341-6. PubMed ID: 16101010
    [Abstract] [Full Text] [Related]

  • 26. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
    Zhang H, LeCulyse E, Liu L, Hu M, Matoney L, Zhu W, Yan B.
    Arch Biochem Biophys; 1999 Aug 01; 368(1):14-22. PubMed ID: 10415106
    [Abstract] [Full Text] [Related]

  • 27. Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors.
    Huss JM, Kasper CB.
    Mol Pharmacol; 2000 Jul 01; 58(1):48-57. PubMed ID: 10860926
    [Abstract] [Full Text] [Related]

  • 28. Regulation of cyp3a gene transcription by the pregnane x receptor.
    Goodwin B, Redinbo MR, Kliewer SA.
    Annu Rev Pharmacol Toxicol; 2002 Jul 01; 42():1-23. PubMed ID: 11807162
    [Abstract] [Full Text] [Related]

  • 29. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.
    Zhang J, Kuehl P, Green ED, Touchman JW, Watkins PB, Daly A, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Wrighton SA, Hancock M, Kim RB, Strom S, Thummel K, Russell CG, Hudson JR, Schuetz EG, Boguski MS.
    Pharmacogenetics; 2001 Oct 01; 11(7):555-72. PubMed ID: 11668216
    [Abstract] [Full Text] [Related]

  • 30. CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
    Tippin TK, Hamilton G, Moore L, Beaudet EJ, Jolley S, Brodie TA, Andrews RC, Becherer JD, McDougald DL, Gaul MD, Hoivik DJ, Mellon-Kusibab K, Lehmann J, Kliewer S, Novick S, Laethem R, Zhao Z, LeCluyse EL.
    Drug Metab Dispos; 2003 Jul 01; 31(7):870-7. PubMed ID: 12814963
    [Abstract] [Full Text] [Related]

  • 31. A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction.
    Vignati LA, Bogni A, Grossi P, Monshouwer M.
    Toxicology; 2004 Jun 01; 199(1):23-33. PubMed ID: 15125996
    [Abstract] [Full Text] [Related]

  • 32. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
    Staudinger J, Liu Y, Madan A, Habeebu S, Klaassen CD.
    Drug Metab Dispos; 2001 Nov 01; 29(11):1467-72. PubMed ID: 11602523
    [Abstract] [Full Text] [Related]

  • 33. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
    Zhang J, Huang W, Qatanani M, Evans RM, Moore DD.
    J Biol Chem; 2004 Nov 19; 279(47):49517-22. PubMed ID: 15358766
    [Abstract] [Full Text] [Related]

  • 34. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
    Healan-Greenberg C, Waring JF, Kempf DJ, Blomme EA, Tirona RG, Kim RB.
    Drug Metab Dispos; 2008 Mar 19; 36(3):500-7. PubMed ID: 18096673
    [Abstract] [Full Text] [Related]

  • 35. Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators.
    Pascussi JM, Drocourt L, Fabre JM, Maurel P, Vilarem MJ.
    Mol Pharmacol; 2000 Aug 19; 58(2):361-72. PubMed ID: 10908304
    [Abstract] [Full Text] [Related]

  • 36. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P, Zhang J, Dowhan DH, Han Y, Moore DD.
    Pharmacogenomics J; 2002 Aug 19; 2(2):117-26. PubMed ID: 12049174
    [Abstract] [Full Text] [Related]

  • 37. Cytochrome P-450 mRNAs are modulated by dehydroepiandrosterone, nafenopin, and triiodothyronine.
    Singleton DW, Lei XD, Webb SJ, Prough RA, Geoghegan TE.
    Drug Metab Dispos; 1999 Feb 19; 27(2):193-200. PubMed ID: 9929502
    [Abstract] [Full Text] [Related]

  • 38. Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.
    Mikamo E, Harada S, Nishikawa J, Nishihara T.
    Toxicol Appl Pharmacol; 2003 Nov 15; 193(1):66-72. PubMed ID: 14613717
    [Abstract] [Full Text] [Related]

  • 39. Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C.
    Ding X, Staudinger JL.
    Biochem Pharmacol; 2005 Mar 01; 69(5):867-73. PubMed ID: 15710363
    [Abstract] [Full Text] [Related]

  • 40. The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and -metabolizing enzymes in mice.
    Anapolsky A, Teng S, Dixit S, Piquette-Miller M.
    Drug Metab Dispos; 2006 Mar 01; 34(3):405-9. PubMed ID: 16381673
    [Abstract] [Full Text] [Related]

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