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245 related items for PubMed ID: 11953755

  • 1. Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
    Shiau AK, Barstad D, Radek JT, Meyers MJ, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA, Agard DA, Greene GL.
    Nat Struct Biol; 2002 May; 9(5):359-64. PubMed ID: 11953755
    [Abstract] [Full Text] [Related]

  • 2. Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes.
    Meyers MJ, Sun J, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA.
    J Med Chem; 1999 Jul 01; 42(13):2456-68. PubMed ID: 10395487
    [Abstract] [Full Text] [Related]

  • 3. Molecular basis of agonism and antagonism in the oestrogen receptor.
    Brzozowski AM, Pike AC, Dauter Z, Hubbard RE, Bonn T, Engström O, Ohman L, Greene GL, Gustafsson JA, Carlquist M.
    Nature; 1997 Oct 16; 389(6652):753-8. PubMed ID: 9338790
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding.
    Rodriguez AL, Tamrazi A, Collins ML, Katzenellenbogen JA.
    J Med Chem; 2004 Jan 29; 47(3):600-11. PubMed ID: 14736241
    [Abstract] [Full Text] [Related]

  • 5. Novel modes of oestrogen receptor agonism and antagonism by hydroxylated and chlorinated biphenyls, revealed by conformation-specific peptide recognition patterns.
    Sumbayev VV, Jensen JK, Hansen JA, Andreasen PA.
    Mol Cell Endocrinol; 2008 Jun 11; 287(1-2):30-9. PubMed ID: 18343567
    [Abstract] [Full Text] [Related]

  • 6. Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor.
    Gee AC, Carlson KE, Martini PG, Katzenellenbogen BS, Katzenellenbogen JA.
    Mol Endocrinol; 1999 Nov 11; 13(11):1912-23. PubMed ID: 10551784
    [Abstract] [Full Text] [Related]

  • 7. Neuroprotective effects of R,R-tetrahydrochrysene against glutamate-induced cell death through anti-excitotoxic and antioxidant actions involving estrogen receptor-dependent and -independent pathways.
    Xia Y, Xing JZ, Krukoff TL.
    Neuroscience; 2009 Aug 18; 162(2):292-306. PubMed ID: 19410635
    [Abstract] [Full Text] [Related]

  • 8. Simulation of the different biological activities of diethylstilbestrol (DES) on estrogen receptor alpha and estrogen-related receptor gamma.
    Nam K, Marshall P, Wolf RM, Cornell W.
    Biopolymers; 2003 Jan 18; 68(1):130-8. PubMed ID: 12579585
    [Abstract] [Full Text] [Related]

  • 9. Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members.
    Kraichely DM, Sun J, Katzenellenbogen JA, Katzenellenbogen BS.
    Endocrinology; 2000 Oct 18; 141(10):3534-45. PubMed ID: 11014206
    [Abstract] [Full Text] [Related]

  • 10. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
    Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA, Greene GL.
    Cell; 1998 Dec 23; 95(7):927-37. PubMed ID: 9875847
    [Abstract] [Full Text] [Related]

  • 11. Structural aspects of agonism and antagonism in the oestrogen receptor.
    Pike AC, Brzozowski AM, Walton J, Hubbard RE, Bonn T, Gustafsson JA, Carlquist M.
    Biochem Soc Trans; 2000 Dec 23; 28(4):396-400. PubMed ID: 10961927
    [Abstract] [Full Text] [Related]

  • 12. Prediction of ligand binding affinity and orientation of xenoestrogens to the estrogen receptor by molecular dynamics simulations and the linear interaction energy method.
    van Lipzig MM, ter Laak AM, Jongejan A, Vermeulen NP, Wamelink M, Geerke D, Meerman JH.
    J Med Chem; 2004 Feb 12; 47(4):1018-30. PubMed ID: 14761204
    [Abstract] [Full Text] [Related]

  • 13. Implications of the binding of tamoxifen to the coactivator recognition site of the estrogen receptor.
    Kojetin DJ, Burris TP, Jensen EV, Khan SA.
    Endocr Relat Cancer; 2008 Dec 12; 15(4):851-70. PubMed ID: 18755852
    [Abstract] [Full Text] [Related]

  • 14. Overexpression, purification, and crystal structure of native ER alpha LBD.
    Eiler S, Gangloff M, Duclaud S, Moras D, Ruff M.
    Protein Expr Purif; 2001 Jul 12; 22(2):165-73. PubMed ID: 11437591
    [Abstract] [Full Text] [Related]

  • 15. Small-angle X-ray scattering studies on structures of an estrogen-related receptor alpha ligand binding domain and its complexes with ligands and coactivators.
    Jin KS, Park JK, Yoon J, Rho Y, Kim JH, Kim EE, Ree M.
    J Phys Chem B; 2008 Aug 14; 112(32):9603-12. PubMed ID: 18646811
    [Abstract] [Full Text] [Related]

  • 16. Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist.
    Pike AC, Brzozowski AM, Hubbard RE, Bonn T, Thorsell AG, Engström O, Ljunggren J, Gustafsson JA, Carlquist M.
    EMBO J; 1999 Sep 01; 18(17):4608-18. PubMed ID: 10469641
    [Abstract] [Full Text] [Related]

  • 17. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta.
    Sun J, Meyers MJ, Fink BE, Rajendran R, Katzenellenbogen JA, Katzenellenbogen BS.
    Endocrinology; 1999 Feb 01; 140(2):800-4. PubMed ID: 9927308
    [Abstract] [Full Text] [Related]

  • 18. Molecular determinants of ER alpha and ER beta involved in selectivity of 16 alpha-iodo-7 beta estradiol.
    Bhat RA, Stauffer B, Unwalla RJ, Xu Z, Harris HA, Komm BS.
    J Steroid Biochem Mol Biol; 2004 Jan 01; 88(1):17-26. PubMed ID: 15026080
    [Abstract] [Full Text] [Related]

  • 19. Estrogen receptor microarrays: subtype-selective ligand binding.
    Kim SH, Tamrazi A, Carlson KE, Daniels JR, Lee IY, Katzenellenbogen JA.
    J Am Chem Soc; 2004 Apr 21; 126(15):4754-5. PubMed ID: 15080660
    [Abstract] [Full Text] [Related]

  • 20. Comparison of estrogen receptor alpha and beta subtypes based on comparative molecular field analysis (CoMFA).
    Xing L, Welsh WJ, Tong W, Perkins R, Sheehan DM.
    SAR QSAR Environ Res; 1999 Apr 21; 10(2-3):215-37. PubMed ID: 10491851
    [Abstract] [Full Text] [Related]

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