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732 related items for PubMed ID: 11956092

  • 1. Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.
    Geroni C, Marchini S, Cozzi P, Galliera E, Ragg E, Colombo T, Battaglia R, Howard M, D'Incalci M, Broggini M.
    Cancer Res; 2002 Apr 15; 62(8):2332-6. PubMed ID: 11956092
    [Abstract] [Full Text] [Related]

  • 2. Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners.
    Beria I, Baraldi PG, Cozzi P, Caldarelli M, Geroni C, Marchini S, Mongelli N, Romagnoli R.
    J Med Chem; 2004 May 06; 47(10):2611-23. PubMed ID: 15115402
    [Abstract] [Full Text] [Related]

  • 3. Role of glutathione transferases in the mechanism of brostallicin activation.
    Pezzola S, Antonini G, Geroni C, Beria I, Colombo M, Broggini M, Marchini S, Mongelli N, Leboffe L, MacArthur R, Mozzi AF, Federici G, Caccuri AM.
    Biochemistry; 2010 Jan 12; 49(1):226-35. PubMed ID: 19950984
    [Abstract] [Full Text] [Related]

  • 4. Brostallicin (PNU-166196), a new minor groove DNA binder: preclinical and clinical activity.
    Lorusso D, Mainenti S, Pietragalla A, Ferrandina G, Foco G, Masciullo V, Scambia G.
    Expert Opin Investig Drugs; 2009 Dec 12; 18(12):1939-46. PubMed ID: 19938904
    [Abstract] [Full Text] [Related]

  • 5. Elevation of pi class glutathione S-transferase activity in human breast cancer cells by transfection of the GST pi gene and its effect on sensitivity to toxins.
    Moscow JA, Townsend AJ, Cowan KH.
    Mol Pharmacol; 1989 Jul 12; 36(1):22-8. PubMed ID: 2747627
    [Abstract] [Full Text] [Related]

  • 6. Enhancement of in vivo antitumor activity of classical anticancer agents by combination with the new, glutathione-interacting DNA minor groove-binder, brostallicin.
    Sabatino MA, Colombo T, Geroni C, Marchini S, Broggini M.
    Clin Cancer Res; 2003 Nov 01; 9(14):5402-8. PubMed ID: 14614026
    [Abstract] [Full Text] [Related]

  • 7. Expression of human mu or alpha class glutathione S-transferases in stably transfected human MCF-7 breast cancer cells: effect on cellular sensitivity to cytotoxic agents.
    Townsend AJ, Tu CP, Cowan KH.
    Mol Pharmacol; 1992 Feb 01; 41(2):230-6. PubMed ID: 1538704
    [Abstract] [Full Text] [Related]

  • 8. Transfection of glutathione S-transferase (GST)-pi antisense complementary DNA increases the sensitivity of a colon cancer cell line to adriamycin, cisplatin, melphalan, and etoposide.
    Ban N, Takahashi Y, Takayama T, Kura T, Katahira T, Sakamaki S, Niitsu Y.
    Cancer Res; 1996 Aug 01; 56(15):3577-82. PubMed ID: 8758929
    [Abstract] [Full Text] [Related]

  • 9. Antineoplastic drug sensitivity of human MCF-7 breast cancer cells stably transfected with a human alpha class glutathione S-transferase gene.
    Leyland-Jones BR, Townsend AJ, Tu CP, Cowan KH, Goldsmith ME.
    Cancer Res; 1991 Jan 15; 51(2):587-94. PubMed ID: 1985777
    [Abstract] [Full Text] [Related]

  • 10. Multifactorial mechanisms associated with broad cross-resistance of ovarian carcinoma cells selected by cyanomorpholino doxorubicin.
    Lau DH, Lewis AD, Ehsan MN, Sikic BI.
    Cancer Res; 1991 Oct 01; 51(19):5181-7. PubMed ID: 1717140
    [Abstract] [Full Text] [Related]

  • 11. Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
    Wang W, Liu G, Zheng J.
    Eur J Pharmacol; 2007 Jul 30; 568(1-3):61-7. PubMed ID: 17509556
    [Abstract] [Full Text] [Related]

  • 12. Transduction of NIH 3T3 cells with a retrovirus carrying both human MDR1 and glutathione S-transferase pi produces broad-range multidrug resistance.
    Doroshow JH, Metz MZ, Matsumoto L, Winters KA, Sakai M, Muramatsu M, Kane SE.
    Cancer Res; 1995 Sep 15; 55(18):4073-8. PubMed ID: 7664283
    [Abstract] [Full Text] [Related]

  • 13. Alterations in glutathione and glutathione-related enzymes in a multidrug-resistant small cell lung cancer cell line.
    Cole SP, Downes HF, Mirski SE, Clements DJ.
    Mol Pharmacol; 1990 Feb 15; 37(2):192-7. PubMed ID: 1968221
    [Abstract] [Full Text] [Related]

  • 14. Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi.
    Fairchild CR, Moscow JA, O'Brien EE, Cowan KH.
    Mol Pharmacol; 1990 Jun 15; 37(6):801-9. PubMed ID: 1972772
    [Abstract] [Full Text] [Related]

  • 15. Mitomycin C sensitivity in human bladder cancer cells: possible role of glutathione and glutathione transferase in resistance.
    Xu BH, Gupta V, Singh SV.
    Arch Biochem Biophys; 1994 Jan 15; 308(1):164-70. PubMed ID: 8311448
    [Abstract] [Full Text] [Related]

  • 16. Cross-resistance and glutathione-S-transferase-pi levels among four human melanoma cell lines selected for alkylating agent resistance.
    Wang YY, Teicher BA, Shea TC, Holden SA, Rosbe KW, al-Achi A, Henner WD.
    Cancer Res; 1989 Nov 15; 49(22):6185-92. PubMed ID: 2804968
    [Abstract] [Full Text] [Related]

  • 17. Cloning, expression, and biochemical characterization of a functionally novel alpha class glutathione S-transferase with exceptional activity in the glutathione conjugation of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Xia H, Pan SS, Hu X, Srivastava SK, Pal A, Singh SV.
    Arch Biochem Biophys; 1998 May 15; 353(2):337-48. PubMed ID: 9606968
    [Abstract] [Full Text] [Related]

  • 18. Hepsulfam sensitivity in human breast cancer cell lines: the role of glutathione and glutathione S-transferase in resistance.
    Armstrong DK, Gordon GB, Hilton J, Streeper RT, Colvin OM, Davidson NE.
    Cancer Res; 1992 Mar 15; 52(6):1416-21. PubMed ID: 1540950
    [Abstract] [Full Text] [Related]

  • 19. Role of glutathione and glutathione S-transferase in chlorambucil resistance.
    Yang WZ, Begleiter A, Johnston JB, Israels LG, Mowat MR.
    Mol Pharmacol; 1992 Apr 15; 41(4):625-30. PubMed ID: 1569917
    [Abstract] [Full Text] [Related]

  • 20. Expression of a rat glutathione-S-transferase complementary DNA in rat mammary carcinoma cells: impact upon alkylator-induced toxicity.
    Schecter RL, Alaoui-Jamali MA, Woo A, Fahl WE, Batist G.
    Cancer Res; 1993 Oct 15; 53(20):4900-6. PubMed ID: 8402679
    [Abstract] [Full Text] [Related]

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