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241 related items for PubMed ID: 11959813

  • 1. Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-beta.
    Yang YA, Tang B, Robinson G, Hennighausen L, Brodie SG, Deng CX, Wakefield LM.
    Cell Growth Differ; 2002 Mar; 13(3):123-30. PubMed ID: 11959813
    [Abstract] [Full Text] [Related]

  • 2. Unique and redundant roles of Smad3 in TGF-beta-mediated regulation of long bone development in organ culture.
    Alvarez J, Serra R.
    Dev Dyn; 2004 Aug; 230(4):685-99. PubMed ID: 15254903
    [Abstract] [Full Text] [Related]

  • 3. IGF-binding proteins mediate TGF-beta 1-induced apoptosis in bovine mammary epithelial BME-UV1 cells.
    Gajewska M, Motyl T.
    Comp Biochem Physiol C Toxicol Pharmacol; 2004 Oct; 139(1-3):65-75. PubMed ID: 15556067
    [Abstract] [Full Text] [Related]

  • 4. Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells.
    Mithani SK, Balch GC, Shiou SR, Whitehead RH, Datta PK, Beauchamp RD.
    J Surg Res; 2004 Apr; 117(2):296-305. PubMed ID: 15047135
    [Abstract] [Full Text] [Related]

  • 5. Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis.
    Iavnilovitch E, Groner B, Barash I.
    Mol Cancer Res; 2002 Nov; 1(1):32-47. PubMed ID: 12496367
    [Abstract] [Full Text] [Related]

  • 6. Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice.
    Gorska AE, Joseph H, Derynck R, Moses HL, Serra R.
    Cell Growth Differ; 1998 Mar; 9(3):229-38. PubMed ID: 9543389
    [Abstract] [Full Text] [Related]

  • 7. The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis.
    Borton AJ, Frederick JP, Datto MB, Wang XF, Weinstein RS.
    J Bone Miner Res; 2001 Oct; 16(10):1754-64. PubMed ID: 11585338
    [Abstract] [Full Text] [Related]

  • 8. A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.
    Brown KA, Pietenpol JA, Moses HL.
    J Cell Biochem; 2007 May 01; 101(1):9-33. PubMed ID: 17340614
    [Abstract] [Full Text] [Related]

  • 9. Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells.
    Dzwonek J, Preobrazhenska O, Cazzola S, Conidi A, Schellens A, van Dinther M, Stubbs A, Klippel A, Huylebroeck D, ten Dijke P, Verschueren K.
    Mol Cancer Res; 2009 Aug 01; 7(8):1342-53. PubMed ID: 19671686
    [Abstract] [Full Text] [Related]

  • 10. Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells.
    Yanagisawa K, Osada H, Masuda A, Kondo M, Saito T, Yatabe Y, Takagi K, Takahashi T, Takahashi T.
    Oncogene; 1998 Oct 01; 17(13):1743-7. PubMed ID: 9796704
    [Abstract] [Full Text] [Related]

  • 11. TGF-beta-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines.
    Fink SP, Mikkola D, Willson JK, Markowitz S.
    Oncogene; 2003 Mar 06; 22(9):1317-23. PubMed ID: 12618756
    [Abstract] [Full Text] [Related]

  • 12. Targeted disruption of TGF-beta-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury.
    Kobayashi K, Yokote K, Fujimoto M, Yamashita K, Sakamoto A, Kitahara M, Kawamura H, Maezawa Y, Asaumi S, Tokuhisa T, Mori S, Saito Y.
    Circ Res; 2005 Apr 29; 96(8):904-12. PubMed ID: 15790953
    [Abstract] [Full Text] [Related]

  • 13. Mammary gland development in transforming growth factor beta1 null mutant mice: systemic and epithelial effects.
    Ingman WV, Robertson SA.
    Biol Reprod; 2008 Oct 29; 79(4):711-7. PubMed ID: 18614704
    [Abstract] [Full Text] [Related]

  • 14. Smad protein mediated transforming growth factor beta1 induction of apoptosis in the MDPC-23 odontoblast-like cell line.
    He WX, Niu ZY, Zhao SL, Smith AJ.
    Arch Oral Biol; 2005 Nov 29; 50(11):929-36. PubMed ID: 16183370
    [Abstract] [Full Text] [Related]

  • 15. Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4.
    Kretschmer A, Moepert K, Dames S, Sternberger M, Kaufmann J, Klippel A.
    Oncogene; 2003 Oct 02; 22(43):6748-63. PubMed ID: 14555988
    [Abstract] [Full Text] [Related]

  • 16. Menin and TGF-beta superfamily member signaling via the Smad pathway in pituitary, parathyroid and osteoblast.
    Hendy GN, Kaji H, Sowa H, Lebrun JJ, Canaff L.
    Horm Metab Res; 2005 Jun 02; 37(6):375-9. PubMed ID: 16001330
    [Abstract] [Full Text] [Related]

  • 17. Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice.
    Li W, Qiao W, Chen L, Xu X, Yang X, Li D, Li C, Brodie SG, Meguid MM, Hennighausen L, Deng CX.
    Development; 2003 Dec 02; 130(24):6143-53. PubMed ID: 14597578
    [Abstract] [Full Text] [Related]

  • 18. The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice.
    Tannehill-Gregg SH, Kusewitt DF, Rosol TJ, Weinstein M.
    Vet Pathol; 2004 May 02; 41(3):278-82. PubMed ID: 15133179
    [Abstract] [Full Text] [Related]

  • 19. Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population.
    Kordon EC, McKnight RA, Jhappan C, Hennighausen L, Merlino G, Smith GH.
    Dev Biol; 1995 Mar 02; 168(1):47-61. PubMed ID: 7883078
    [Abstract] [Full Text] [Related]

  • 20. Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.
    Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL.
    Cancer Res; 2005 Mar 15; 65(6):2296-302. PubMed ID: 15781643
    [Abstract] [Full Text] [Related]

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