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Journal Abstract Search

137 related items for PubMed ID: 11960662

  • 1. Active conformation of some arylpiperazine postsynaptic 5-HT(1A) receptor antagonists.
    Paluchowska MH, Bojarski AJ, Charakchieva-Minol S, Wesołowska A.
    Eur J Med Chem; 2002 Apr; 37(4):273-83. PubMed ID: 11960662
    [Abstract] [Full Text] [Related]

  • 2. On the bioactive conformation of NAN-190 (1) and MP3022 (2), 5-HT(1A) receptor antagonists.
    Paluchowska MH, Mokrosz MJ, Bojarski A, Wesołowska A, Borycz J, Charakchieva-Minol S, Chojnacka-Wójcik E.
    J Med Chem; 1999 Dec 02; 42(24):4952-60. PubMed ID: 10585205
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
    Orús L, Pérez-Silanes S, Oficialdegui AM, Martínez-Esparza J, Del Castillo JC, Mourelle M, Langer T, Guccione S, Donzella G, Krovat EM, Poptodorov K, Lasheras B, Ballaz S, Hervías I, Tordera R, Del Río J, Monge A.
    J Med Chem; 2002 Sep 12; 45(19):4128-39. PubMed ID: 12213056
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.
    Mensonides-Harsema MM, Liao Y, Böttcher H, Bartoszyk GD, Greiner HE, Harting J, de Boer P, Wikström HV.
    J Med Chem; 2000 Feb 10; 43(3):432-9. PubMed ID: 10669570
    [Abstract] [Full Text] [Related]

  • 5. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2005 Mar 15; 13(6):2293-303. PubMed ID: 15727878
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and structure-activity relationships of a new model of arylpiperazines. 5. Study of the physicochemical influence of the pharmacophore on 5-HT(1a)/alpha(1)-adrenergic receptor affinity: synthesis of a new derivative with mixed 5-HT(1a)/d(2) antagonist properties.
    López-Rodríguez ML, Morcillo MJ, Fernández E, Porras E, Orensanz L, Beneytez ME, Manzanares J, Fuentes JA.
    J Med Chem; 2001 Jan 18; 44(2):186-97. PubMed ID: 11170628
    [Abstract] [Full Text] [Related]

  • 7. Arylpiperazine derivatives acting at 5-HT(1A) receptors.
    López-Rodríguez ML, Ayala D, Benhamú B, Morcillo MJ, Viso A.
    Curr Med Chem; 2002 Feb 18; 9(4):443-69. PubMed ID: 11945120
    [Abstract] [Full Text] [Related]

  • 8. Interaction of 1,2,4-substituted piperazines, new serotonin receptor ligands, with 5-HT1A and 5-HT2A receptors.
    Chilmonczyk Z, Cybulski M, Iskra-Jopa J, Chojnacka-Wójcik E, Tatarczyńska E, Kłodzińska A, Leś A, Bronowska A, Sylte I.
    Farmaco; 2002 Apr 18; 57(4):285-301. PubMed ID: 11989808
    [Abstract] [Full Text] [Related]

  • 9. S 14506: novel receptor coupling at 5-HT(1A) receptors.
    Milligan G, Kellett E, Dacquet C, Dubreuil V, Jacoby E, Millan MJ, Lavielle G, Spedding M.
    Neuropharmacology; 2001 Mar 18; 40(3):334-44. PubMed ID: 11166326
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors.
    Asproni B, Pau A, Bitti M, Melosu M, Cerri R, Dazzi L, Seu E, Maciocco E, Sanna E, Busonero F, Talani G, Pusceddu L, Altomare C, Trapani G, Biggio G.
    J Med Chem; 2002 Oct 10; 45(21):4655-68. PubMed ID: 12361392
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, 5-HT1A and 5-HT2A receptor activity of new 1-phenylpiperazinylpropyl derivatives with arylalkyl substituents in position 7 of purine-2,6-dione.
    Chloń G, Pawłowski M, Duszyńska B, Szaro A, Tatarczńska E, Kłodzińska AL, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2001 Oct 10; 53(4):359-68. PubMed ID: 11990082
    [Abstract] [Full Text] [Related]

  • 12. Correlation between low/high affinity ratios for 5-HT(1A) receptors and intrinsic activity.
    Assié MB, Cosi C, Koek W.
    Eur J Pharmacol; 1999 Dec 10; 386(1):97-103. PubMed ID: 10611469
    [Abstract] [Full Text] [Related]

  • 13. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D.
    J Med Chem; 2004 May 06; 47(10):2659-66. PubMed ID: 15115407
    [Abstract] [Full Text] [Related]

  • 14. Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.
    Lacivita E, Patarnello D, Stroth N, Caroli A, Niso M, Contino M, De Giorgio P, Di Pilato P, Colabufo NA, Berardi F, Perrone R, Svenningsson P, Hedlund PB, Leopoldo M.
    J Med Chem; 2012 Jul 26; 55(14):6375-80. PubMed ID: 22738316
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity.
    Bojarski AJ, Kowalski P, Kowalska T, Duszyńska B, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2002 Dec 26; 10(12):3817-27. PubMed ID: 12413835
    [Abstract] [Full Text] [Related]

  • 16. trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
    Perrone R, Berardi F, Colabufo NA, Leopoldo M, Lacivita E, Tortorella V, Leonardi A, Poggesi E, Testa R.
    J Med Chem; 2001 Dec 06; 44(25):4431-42. PubMed ID: 11728188
    [Abstract] [Full Text] [Related]

  • 17. Memory of an operant response and of depressed mood retained in activation states of 5-HT(1A) receptors: evidence from rodent models.
    Colpaert FC, Bruins Slot LA, Koek W, Dupuis DS.
    Behav Brain Res; 2000 Dec 20; 117(1-2):41-51. PubMed ID: 11099756
    [Abstract] [Full Text] [Related]

  • 18. Improvement in the selectivity and metabolic stability of the serotonin 5-HT(1A) ligand, S 15535: a series of cis- and trans-2-(arylcycloalkylamine) 1-indanols.
    Peglion JL, Goument B, Despaux N, Charlot V, Giraud H, Nisole C, Newman-Tancredi A, Dekeyne A, Bertrand M, Genissel P, Millan MJ.
    J Med Chem; 2002 Jan 03; 45(1):165-76. PubMed ID: 11754589
    [Abstract] [Full Text] [Related]

  • 19. Influence of the terminal amide fragment geometry in some 3-arylideneindolin-2(1H)-ones on their 5-HT1A/5-HT2A receptor activity.
    Mokrosz MJ, Charakchieva-Minol S, Kozioł A, Kłodzińska A, Chojnacka-Wójcik E.
    Bioorg Med Chem Lett; 2001 May 07; 11(9):1229-31. PubMed ID: 11354383
    [Abstract] [Full Text] [Related]

  • 20. Effect of linking bridge modifications on the 5-HT1A receptor activity of some 4-(omega-benzotriazol-1-yl)alkyl-1-(2-methoxy-phenyl)piperazines.
    Paluchowska MH, Kłodzińska A, Tatarczyńska E, Szaro A, Chojnacka-Wójcik E.
    Pol J Pharmacol; 1998 May 07; 50(4-5):341-7. PubMed ID: 10091719
    [Abstract] [Full Text] [Related]

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