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129 related items for PubMed ID: 11961058

  • 1. Bryostatin 1 increases 1-beta-D-arabinofuranosylcytosine-induced cytochrome c release and apoptosis in human leukemia cells ectopically expressing Bcl-x(L).
    Wang Z, Wang S, Dai Y, Grant S.
    J Pharmacol Exp Ther; 2002 May; 301(2):568-77. PubMed ID: 11961058
    [Abstract] [Full Text] [Related]

  • 2. Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells through disparate mechanisms.
    Wang S, Wang Z, Grant S.
    Mol Pharmacol; 2003 Jan; 63(1):232-42. PubMed ID: 12488556
    [Abstract] [Full Text] [Related]

  • 3. Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells.
    Wang S, Wang Z, Dent P, Grant S.
    Blood; 2003 May 01; 101(9):3648-57. PubMed ID: 12522001
    [Abstract] [Full Text] [Related]

  • 4. Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.
    Wang S, Vrana JA, Bartimole TM, Freemerman AJ, Jarvis WD, Kramer LB, Krystal G, Dent P, Grant S.
    Mol Pharmacol; 1997 Dec 01; 52(6):1000-9. PubMed ID: 9396780
    [Abstract] [Full Text] [Related]

  • 5. Potentiation of 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial damage and apoptosis in human leukemia cells (U937) overexpressing bcl-2 by the kinase inhibitor 7-hydroxystaurosporine (UCN-01).
    Tang L, Boise LH, Dent P, Grant S.
    Biochem Pharmacol; 2000 Nov 15; 60(10):1445-56. PubMed ID: 11020446
    [Abstract] [Full Text] [Related]

  • 6. Bryostatin 1 enhances paclitaxel-induced mitochondrial dysfunction and apoptosis in human leukemia cells (U937) ectopically expressing Bcl-xL.
    Wang S, Wang Z, Boise LH, Dent P, Grant S.
    Leukemia; 1999 Oct 15; 13(10):1564-73. PubMed ID: 10516758
    [Abstract] [Full Text] [Related]

  • 7. Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells exposed to bryostatin 1 and flavopiridol.
    Cartee L, Maggio SC, Smith R, Sankala HM, Dent P, Grant S.
    Mol Cancer Ther; 2003 Jan 15; 2(1):83-93. PubMed ID: 12533676
    [Abstract] [Full Text] [Related]

  • 8. Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA.
    Grant S, Jarvis WD, Swerdlow PS, Turner AJ, Traylor RS, Wallace HJ, Lin PS, Pettit GR, Gewirtz DA.
    Cancer Res; 1992 Nov 15; 52(22):6270-8. PubMed ID: 1423273
    [Abstract] [Full Text] [Related]

  • 9. Modulation of protein kinase C activity and calcium-sensitive isoform expression in human myeloid leukemia cells by bryostatin 1: relationship to differentiation and ara-C-induced apoptosis.
    Grant S, Turner AJ, Freemerman AJ, Wang Z, Kramer L, Jarvis WD.
    Exp Cell Res; 1996 Oct 10; 228(1):65-75. PubMed ID: 8892972
    [Abstract] [Full Text] [Related]

  • 10. Potentiation of ara-C-induced apoptosis by the protein kinase C activator bryostatin 1 in human leukemia cells (HL-60) involves a process dependent upon c-Myc.
    Chelliah J, Freemerman AJ, Wu-Pong S, Jarvis WD, Grant S.
    Biochem Pharmacol; 1997 Sep 01; 54(5):563-73. PubMed ID: 9337072
    [Abstract] [Full Text] [Related]

  • 11. Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.
    Harvey S, Decker R, Dai Y, Schaefer G, Tang L, Kramer L, Dent P, Grant S.
    Clin Cancer Res; 2001 Feb 01; 7(2):320-30. PubMed ID: 11234887
    [Abstract] [Full Text] [Related]

  • 12. Effects of bryostatin 1 and calcium ionophore (A23187) on apoptosis and differentiation in human myeloid leukemia cells (HL-60) following 1-beta-D-arabinofuranosylcytosine exposure.
    Vrana JA, Rao AS, Wang Z, Jarvis WD, Grant S.
    Int J Oncol; 1998 Apr 01; 12(4):927-34. PubMed ID: 9499457
    [Abstract] [Full Text] [Related]

  • 13. Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells.
    Jarvis WD, Povirk LF, Turner AJ, Traylor RS, Gewirtz DA, Pettit GR, Grant S.
    Biochem Pharmacol; 1994 Mar 02; 47(5):839-52. PubMed ID: 8135859
    [Abstract] [Full Text] [Related]

  • 14. Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.
    Wang Z, Van Tuyle G, Conrad D, Fisher PB, Dent P, Grant S.
    Cancer Res; 1999 Mar 15; 59(6):1259-67. PubMed ID: 10096557
    [Abstract] [Full Text] [Related]

  • 15. In vitro effects of bryostatin 1 on the metabolism and cytotoxicity of 1-beta-D-arabinofuranosylcytosine in human leukemia cells.
    Grant S, Boise L, Westin E, Howe C, Pettit GR, Turner A, McCrady C.
    Biochem Pharmacol; 1991 Jul 25; 42(4):853-67. PubMed ID: 1867641
    [Abstract] [Full Text] [Related]

  • 16. Flavopiridol and histone deacetylase inhibitors promote mitochondrial injury and cell death in human leukemia cells that overexpress Bcl-2.
    Dasmahapatra G, Almenara JA, Grant S.
    Mol Pharmacol; 2006 Jan 25; 69(1):288-98. PubMed ID: 16219908
    [Abstract] [Full Text] [Related]

  • 17. Effect of AS101 on bryostatin 1-mediated differentiation induction, cell cycle arrest, and modulation of drug-induced apoptosis in human myeloid leukemia cells.
    Rao AS, Freemerman AJ, Jarvis WD, Chelliah J, Bear HD, Mikkelsen R, Grant S.
    Leukemia; 1996 Jul 25; 10(7):1150-8. PubMed ID: 8683995
    [Abstract] [Full Text] [Related]

  • 18. Human THP-1 monocytic leukemic cells induced to undergo monocytic differentiation by bryostatin 1 are refractory to proteasome inhibitor-induced apoptosis.
    Chen C, Lin H, Karanes C, Pettit GR, Chen BD.
    Cancer Res; 2000 Aug 15; 60(16):4377-85. PubMed ID: 10969781
    [Abstract] [Full Text] [Related]

  • 19. Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling.
    Jarvis WD, Fornari FA, Tombes RM, Erukulla RK, Bittman R, Schwartz GK, Dent P, Grant S.
    Mol Pharmacol; 1998 Nov 15; 54(5):844-56. PubMed ID: 9804619
    [Abstract] [Full Text] [Related]

  • 20. Effects of bryostatin 1 and rGM-CSF on the metabolism of 1-beta-D-arabinofuranosylcytosine in human leukaemic myeloblasts.
    Grant S, Jarvis WD, Turner AJ, Wallace HJ, Pettit GR.
    Br J Haematol; 1992 Nov 15; 82(3):522-8. PubMed ID: 1486032
    [Abstract] [Full Text] [Related]

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