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202 related items for PubMed ID: 11965494

  • 1. PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway.
    Wan X, Yokoyama Y, Shinohara A, Takahashi Y, Tamaya T.
    Cell Death Differ; 2002 Apr; 9(4):414-20. PubMed ID: 11965494
    [Abstract] [Full Text] [Related]

  • 2. PTEN augments doxorubicin-induced apoptosis in PTEN-null Ishikawa cells.
    Wan X, Li J, Xie X, Lu W.
    Int J Gynecol Cancer; 2007 Apr; 17(4):808-12. PubMed ID: 17359293
    [Abstract] [Full Text] [Related]

  • 3. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME, Gagnon V, Mathieu I, Parent S, Asselin E.
    Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356
    [Abstract] [Full Text] [Related]

  • 4. Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway.
    Zhang J, Choi Y, Mavromatis B, Lichtenstein A, Li W.
    Oncogene; 2003 Sep 18; 22(40):6289-95. PubMed ID: 13679867
    [Abstract] [Full Text] [Related]

  • 5. PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells.
    Choi Y, Zhang J, Murga C, Yu H, Koller E, Monia BP, Gutkind JS, Li W.
    Oncogene; 2002 Aug 08; 21(34):5289-300. PubMed ID: 12149650
    [Abstract] [Full Text] [Related]

  • 6. [Sensitivity of PTEN gene-transfected endometrial carcinoma cell line to doxorubicin-induced apoptosis].
    Wan XY, Mao YY, Yokoyama Y.
    Zhonghua Zhong Liu Za Zhi; 2005 Sep 08; 27(9):513-5. PubMed ID: 16438844
    [Abstract] [Full Text] [Related]

  • 7. PTEN induces G(1) cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells.
    Zhu X, Kwon CH, Schlosshauer PW, Ellenson LH, Baker SJ.
    Cancer Res; 2001 Jun 01; 61(11):4569-75. PubMed ID: 11389092
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.
    Edwards LA, Thiessen B, Dragowska WH, Daynard T, Bally MB, Dedhar S.
    Oncogene; 2005 May 19; 24(22):3596-605. PubMed ID: 15782140
    [Abstract] [Full Text] [Related]

  • 9. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells.
    Kandasamy K, Srivastava RK.
    Cancer Res; 2002 Sep 01; 62(17):4929-37. PubMed ID: 12208743
    [Abstract] [Full Text] [Related]

  • 10. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.
    Haas-Kogan D, Shalev N, Wong M, Mills G, Yount G, Stokoe D.
    Curr Biol; 1998 Oct 22; 8(21):1195-8. PubMed ID: 9799739
    [Abstract] [Full Text] [Related]

  • 11. Indole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line.
    Howells LM, Gallacher-Horley B, Houghton CE, Manson MM, Hudson EA.
    Mol Cancer Ther; 2002 Nov 22; 1(13):1161-72. PubMed ID: 12479697
    [Abstract] [Full Text] [Related]

  • 12. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM, Tazzari PL, Tabellini G, Bortul R, Billi AM, Manzoli L, Ruggeri A, Conte R, Cocco L.
    Leukemia; 2003 Sep 22; 17(9):1794-805. PubMed ID: 12970779
    [Abstract] [Full Text] [Related]

  • 13. The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells.
    She QB, Solit DB, Ye Q, O'Reilly KE, Lobo J, Rosen N.
    Cancer Cell; 2005 Oct 22; 8(4):287-97. PubMed ID: 16226704
    [Abstract] [Full Text] [Related]

  • 14. Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line.
    Lee S, Choi EJ, Jin C, Kim DH.
    Gynecol Oncol; 2005 Apr 22; 97(1):26-34. PubMed ID: 15790433
    [Abstract] [Full Text] [Related]

  • 15. [PTEN expression in endometrial cancer and the prognosis].
    Kanamori Y, Uegaki K, Kigawa J, Terakawa N.
    Nihon Rinsho; 2004 Oct 22; 62 Suppl 10():406-9. PubMed ID: 15535277
    [No Abstract] [Full Text] [Related]

  • 16. Correlation between loss of PTEN expression and Akt phosphorylation in endometrial carcinoma.
    Kanamori Y, Kigawa J, Itamochi H, Shimada M, Takahashi M, Kamazawa S, Sato S, Akeshima R, Terakawa N.
    Clin Cancer Res; 2001 Apr 22; 7(4):892-5. PubMed ID: 11309338
    [Abstract] [Full Text] [Related]

  • 17. Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways.
    Liu W, Asa SL, Fantus IG, Walfish PG, Ezzat S.
    Am J Pathol; 2002 Feb 22; 160(2):511-9. PubMed ID: 11839571
    [Abstract] [Full Text] [Related]

  • 18. PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
    Kim S, Domon-Dell C, Wang Q, Chung DH, Di Cristofano A, Pandolfi PP, Freund JN, Evers BM.
    Gastroenterology; 2002 Oct 22; 123(4):1163-78. PubMed ID: 12360479
    [Abstract] [Full Text] [Related]

  • 19. Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
    Liu JL, Sheng X, Hortobagyi ZK, Mao Z, Gallick GE, Yung WK.
    Mol Cell Biol; 2005 Jul 22; 25(14):6211-24. PubMed ID: 15988030
    [Abstract] [Full Text] [Related]

  • 20. Growth suppression activity of the PTEN tumor suppressor gene in human endometrial cancer cells.
    Lilja JF, Wu D, Reynolds RK, Lin J.
    Anticancer Res; 2001 Jul 22; 21(3B):1969-74. PubMed ID: 11497285
    [Abstract] [Full Text] [Related]


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