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Journal Abstract Search

108 related items for PubMed ID: 11983519

  • 1.
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  • 2. QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?
    Campos J, Núñez MC, Conejo-García A, Sánchez-Martín RM, Hernández-Alcoceba R, Rodríguez-González A, Lacal JC, Gallo MA, Espinosa A.
    Curr Med Chem; 2003 Jul; 10(13):1095-112. PubMed ID: 12678804
    [Abstract] [Full Text] [Related]

  • 3. Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line.
    Gómez-Pérez V, McSorley T, See Too WC, Konrad M, Campos JM.
    ChemMedChem; 2012 Apr; 7(4):663-9. PubMed ID: 22278967
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  • 4. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1).
    Schiaffino-Ortega S, Baglioni E, Mariotto E, Bortolozzi R, Serrán-Aguilera L, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Hurtado-Guerrero R, Marco C, Basso G, Viola G, Entrena A, López-Cara LC.
    Sci Rep; 2016 Mar 31; 6():23793. PubMed ID: 27029499
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  • 7. LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase.
    Campos J, del Carmen Núñez M, Rodríguez V, Entrena A, Hernández-Alcoceba R, Fernández F, Lacal JC, Gallo MA, Espinosa A.
    Eur J Med Chem; 2001 Mar 31; 36(3):215-25. PubMed ID: 11337100
    [Abstract] [Full Text] [Related]

  • 8. (Q)SAR studies to design new human choline kinase inhibitors as antiproliferative drugs.
    Campos JM, Sánchez-Martín RM, Conejo-García A, Entrena A, Gallo MA, Espinosa A.
    Curr Med Chem; 2006 Mar 31; 13(11):1231-48. PubMed ID: 16712467
    [Abstract] [Full Text] [Related]

  • 9. QSAR of 1,1'-(1,2-ethylenebisbenzyl)bis(4-substitutedpyridinium) dibromides as choline kinase inhibitors: a different approach for antiproliferative drug design.
    Campos J, Núñez MC, Rodríguez V, Gallo MA, Espinosa A.
    Bioorg Med Chem Lett; 2000 Apr 17; 10(8):767-70. PubMed ID: 10782682
    [Abstract] [Full Text] [Related]

  • 10. New non-symmetrical choline kinase inhibitors.
    Schiaffino-Ortega S, López-Cara LC, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Espinosa A, Marco C, Entrena A.
    Bioorg Med Chem; 2013 Nov 15; 21(22):7146-54. PubMed ID: 24080101
    [Abstract] [Full Text] [Related]

  • 11. Influence of the linker in bispyridium compounds on the inhibition of human choline kinase.
    Conejo-García A, Báñez-Coronel M, Sánchez-Martín RM, Rodríguez-González A, Ramos A, Ramírez de Molina A, Espinosa A, Gallo MA, Campos JM, Lacal JC.
    J Med Chem; 2004 Oct 21; 47(22):5433-40. PubMed ID: 15481981
    [Abstract] [Full Text] [Related]

  • 12. New more polar symmetrical bipyridinic compounds: new strategy for the inhibition of choline kinase α1.
    Castro-Navas FF, Schiaffino-Ortega S, Carrasco-Jimenez MP, Ríos-Marco P, Marco C, Espinosa A, Gallo MA, Mariotto E, Basso G, Viola G, Entrena-Guadix A, López-Cara LC.
    Future Med Chem; 2015 Oct 21; 7(4):417-36. PubMed ID: 25875870
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological activity of new bispyridinium salts of 4,4'-bispyridyl-5,5'-perfluoroalkyl-2,2'-bisoxazoles.
    Martín-Cantalejo Y, Sáez B, Monterde MI, Murillo MT, Braña MF.
    Eur J Med Chem; 2011 Nov 21; 46(11):5662-7. PubMed ID: 21996467
    [Abstract] [Full Text] [Related]

  • 14. Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors.
    Conejo-García A, Campos JM, Sánchez-Martín RM, Gallo MA, Espinosa A.
    J Med Chem; 2003 Aug 14; 46(17):3754-7. PubMed ID: 12904080
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors.
    Rubio-Ruíz B, Conejo-García A, Ríos-Marco P, Carrasco-Jiménez MP, Segovia J, Marco C, Gallo MA, Espinosa A, Entrena A.
    Eur J Med Chem; 2012 Apr 14; 50():154-62. PubMed ID: 22348828
    [Abstract] [Full Text] [Related]

  • 16. A novel 4,4'-bispyridyl-5,5'-perfluoroalkyl-2,2'-bisoxazol with antitumoral activity via cell cycle arrest and induction of apoptosis.
    Báñez-Coronel M, Rodríguez-González A, Martín-Cantalejo Y, Sáez B, Soto J, Villa MJ, Braña MF, Lacal JC.
    Int J Oncol; 2004 Oct 14; 25(4):1097-103. PubMed ID: 15375561
    [Abstract] [Full Text] [Related]

  • 17. A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products.
    Estévez-Braun A, Ravelo AG, Pérez-Sacau E, Lacal JC.
    Clin Transl Oncol; 2015 Jan 14; 17(1):74-84. PubMed ID: 25472447
    [Abstract] [Full Text] [Related]

  • 18. Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors.
    Rubbini G, Buades-Martín AB, Kimatrai-Salvador M, Entrena A, Gallo-Mezo MÁ, Ríos-Marco P, Marco C, Mattiuzzo E, Bortolozzi R, Mariotto E, Greco FA, Macchiarulo A, Carrasco-Jiménez MP, Viola G, López-Cara LC.
    Future Med Chem; 2018 Aug 01; 10(15):1769-1786. PubMed ID: 30043647
    [Abstract] [Full Text] [Related]

  • 19. NMR QSAR model for the analysis of 4-(5-arylamino-1,3,4-thiadiazol-2-yl)benzene-1,3-diols.
    Matysiak J, Niewiadomy A, Paw B, Dybała I.
    Arch Pharm (Weinheim); 2011 May 01; 344(5):340-4. PubMed ID: 21290429
    [Abstract] [Full Text] [Related]

  • 20. Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
    Al-Saffar NM, Troy H, Ramírez de Molina A, Jackson LE, Madhu B, Griffiths JR, Leach MO, Workman P, Lacal JC, Judson IR, Chung YL.
    Cancer Res; 2006 Jan 01; 66(1):427-34. PubMed ID: 16397258
    [Abstract] [Full Text] [Related]

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