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417 related items for PubMed ID: 11990082

  • 21. Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.
    López-Rodríguez ML, Rosado ML, Benhamú B, Morcillo MJ, Sanz AM, Orensanz L, Beneitez ME, Fuentes JA, Manzanares J.
    J Med Chem; 1996 Oct 25; 39(22):4439-50. PubMed ID: 8893838
    [Abstract] [Full Text] [Related]

  • 22. Pharmacological analysis of the hypothermic effects of NAN-190 and its analogs, postsynaptic 5-HT1A receptor antagonists, in mice.
    Wesołowska A, Borycz J, Paluchowska MH, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2002 Oct 25; 54(4):391-9. PubMed ID: 12523493
    [Abstract] [Full Text] [Related]

  • 23. Synthesis of new hexahydro- and octahydropyrido[1,2-c]pyrimidine derivatives with an arylpiperazine moiety as ligands for 5-HT1A and 5-HT2A receptors. Part 4.
    Herold F, Król M, Kleps J, Nowak G.
    Eur J Med Chem; 2006 Jan 25; 41(1):125-34. PubMed ID: 16263195
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  • 24. Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors.
    Delgado M, Caicoya AG, Greciano V, Benhamú B, López-Rodríguez ML, Fernández-Alfonso MS, Pozo MA, Manzanares J, Fuentes JA.
    Eur J Pharmacol; 2005 Mar 21; 511(1):9-19. PubMed ID: 15777774
    [Abstract] [Full Text] [Related]

  • 25. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
    [Abstract] [Full Text] [Related]

  • 26. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
    López-Rodríguez ML, Morcillo MJ, Rovat TK, Fernández E, Vicente B, Sanz AM, Hernández M, Orensanz L.
    J Med Chem; 1999 Jan 14; 42(1):36-49. PubMed ID: 9888831
    [Abstract] [Full Text] [Related]

  • 27. Synthesis and 5-HT1A/5-HT2A receptor activity of new N-[3-(4-phenylpiperazin-1-yl)-propyl] derivatives of 3-spiro-cyclohexanepyrrolidine-2,5-dione and 3-spiro-beta-tetralonepyrrolidine-2,5-dione.
    Obniska J, Pawłowski M, Kołaczkowski M, Czopek A, Duszyńska B, Klodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2003 Jan 14; 55(4):553-7. PubMed ID: 14581713
    [Abstract] [Full Text] [Related]

  • 28. Interaction of 1,2,4-substituted piperazines, new serotonin receptor ligands, with 5-HT1A and 5-HT2A receptors.
    Chilmonczyk Z, Cybulski M, Iskra-Jopa J, Chojnacka-Wójcik E, Tatarczyńska E, Kłodzińska A, Leś A, Bronowska A, Sylte I.
    Farmaco; 2002 Apr 14; 57(4):285-301. PubMed ID: 11989808
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  • 29. Synthesis and pharmacological characterization of novel 6-fluorochroman derivatives as potential 5-HT1A receptor antagonists.
    Yasunaga T, Kimura T, Naito R, Kontani T, Wanibuchi F, Yamashita H, Nomura T, Tsukamoto S, Yamaguchi T, Mase T.
    J Med Chem; 1998 Jul 16; 41(15):2765-78. PubMed ID: 9667967
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  • 30. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding.
    Metwally KA, Dukat M, Egan CT, Smith C, DuPre A, Gauthier CB, Herrick-Davis K, Teitler M, Glennon RA.
    J Med Chem; 1998 Dec 03; 41(25):5084-93. PubMed ID: 9836624
    [Abstract] [Full Text] [Related]

  • 31. New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.
    el Ahmad Y, Laurent E, Maillet P, Talab A, Teste JF, Dokhan R, Tran G, Ollivier R.
    J Med Chem; 1997 Mar 14; 40(6):952-60. PubMed ID: 9083484
    [Abstract] [Full Text] [Related]

  • 32. Antagonism of (+)WAY 100135 to behavioral, hypothermic and corticosterone effects induced by 8-OH-DPAT.
    Przegaliński E, Filip M, Budziszewska B, Chojnacka-Wójcik E.
    Pol J Pharmacol; 1994 Mar 14; 46(1-2):21-7. PubMed ID: 7981767
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  • 33. Synthesis by microwave irradiation and binding properties of novel 5-HT(1A) receptor ligands.
    Caliendo G, Fiorino F, Perissutti E, Severino B, Gessi S, Cattabriga E, Borea PA, Santagada V.
    Eur J Med Chem; 2001 Mar 14; 36(11-12):873-86. PubMed ID: 11755230
    [Abstract] [Full Text] [Related]

  • 34. Structure-activity relationship studies of CNS agents. Part 38. Novel 1,4-benzoxazin-3(4H)-one, 1,2-benzoxazolin-3-one and 1,3-benzoxazolin-2,4-dione arylpiperazine derivatives with different 5-HT1A and antagonistic 5-HT2A activities.
    Mokrosz MJ, Kowalski P, Kowalska T, Majka Z, Duszyńska B, Bojarski AJ, Fruziński A, Karolak-Wojciechowska J, Wesołowska A, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Arch Pharm (Weinheim); 1999 Nov 14; 332(11):373-9. PubMed ID: 10605377
    [Abstract] [Full Text] [Related]

  • 35. New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation.
    Chłoń-Rzepa G, Zmudzki P, Satała G, Duszyńska B, Partyka A, Wróbel D, Jastrzębska-Więsek M, Wesołowska A, Bojarski AJ, Pawłowski M, Zajdel P.
    Pharmacol Rep; 2013 Nov 14; 65(1):15-29. PubMed ID: 23563020
    [Abstract] [Full Text] [Related]

  • 36. Synthesis and preliminary pharmacological evaluation of imidazo[2,1-f]purine-2,4-dione derivatives.
    Zagórska A, Jurczyk S, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E.
    Eur J Med Chem; 2009 Nov 14; 44(11):4288-96. PubMed ID: 19679379
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  • 37. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
    Berardi F, Colabufo NA, Giudice G, Perrone R, Tortorella V, Govoni S, Lucchi L.
    J Med Chem; 1996 Jan 05; 39(1):176-82. PubMed ID: 8568804
    [Abstract] [Full Text] [Related]

  • 38. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
    Tapia I, Alonso-Cires L, López-Tudanca PL, Mosquera R, Labeaga L, Innerárity A, Orjales A.
    J Med Chem; 1999 Jul 29; 42(15):2870-80. PubMed ID: 10425096
    [Abstract] [Full Text] [Related]

  • 39. Synthesis and 5-HT1A/5-HT2A activity of some butyl analogs in the group of phenylpiperazine alkyl pyrimido[2,1-f]theophyllines.
    Kołaczkowski M, Zajdel P, Fhid O, Duszyńska B, Tatarczyńska E, Pawłowski M.
    Pharmacol Rep; 2005 Jul 29; 57(2):229-35. PubMed ID: 15886422
    [Abstract] [Full Text] [Related]

  • 40. 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.
    Kuipers W, Kruse CG, van Wijngaarden I, Standaar PJ, Tulp MT, Veldman N, Spek AL, IJzerman AP.
    J Med Chem; 1997 Jan 31; 40(3):300-12. PubMed ID: 9022796
    [Abstract] [Full Text] [Related]

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