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155 related items for PubMed ID: 11990782
1. P glycoprotein and the mechanism of multidrug resistance. Váradi A, Szakács G, Bakos E, Sarkadi B. Novartis Found Symp; 2002; 243():54-65; discussion 65-8, 180-5. PubMed ID: 11990782 [Abstract] [Full Text] [Related]
2. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein. Maki N, Moitra K, Silver C, Ghosh P, Chattopadhyay A, Dey S. Biochemistry; 2006 Feb 28; 45(8):2739-51. PubMed ID: 16489767 [Abstract] [Full Text] [Related]
3. The catalytic cycle of P-glycoprotein. Senior AE, al-Shawi MK, Urbatsch IL. FEBS Lett; 1995 Dec 27; 377(3):285-9. PubMed ID: 8549739 [Abstract] [Full Text] [Related]
4. Bacterial multidrug resistance mediated by a homologue of the human multidrug transporter P-glycoprotein. Konings WN, Poelarends GJ. IUBMB Life; 2002 Dec 27; 53(4-5):213-8. PubMed ID: 12120998 [Abstract] [Full Text] [Related]
5. Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains. Liu R, Sharom FJ. Biochemistry; 1996 Sep 10; 35(36):11865-73. PubMed ID: 8794769 [Abstract] [Full Text] [Related]
6. Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport. Hrycyna CA, Airan LE, Germann UA, Ambudkar SV, Pastan I, Gottesman MM. Biochemistry; 1998 Sep 29; 37(39):13660-73. PubMed ID: 9753453 [Abstract] [Full Text] [Related]
7. A molecular understanding of the catalytic cycle of the nucleotide-binding domain of the ABC transporter HlyB. Zaitseva J, Jenewein S, Oswald C, Jumpertz T, Holland IB, Schmitt L. Biochem Soc Trans; 2005 Nov 29; 33(Pt 5):990-5. PubMed ID: 16246029 [Abstract] [Full Text] [Related]
8. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state. Tombline G, Donnelly DJ, Holt JJ, You Y, Ye M, Gannon MK, Nygren CL, Detty MR. Biochemistry; 2006 Jul 04; 45(26):8034-47. PubMed ID: 16800628 [Abstract] [Full Text] [Related]
9. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. Ramachandra M, Ambudkar SV, Chen D, Hrycyna CA, Dey S, Gottesman MM, Pastan I. Biochemistry; 1998 Apr 07; 37(14):5010-9. PubMed ID: 9538020 [Abstract] [Full Text] [Related]
10. Stoichiometry and affinity of nucleotide binding to P-glycoprotein during the catalytic cycle. Qu Q, Russell PL, Sharom FJ. Biochemistry; 2003 Feb 04; 42(4):1170-7. PubMed ID: 12549939 [Abstract] [Full Text] [Related]
11. Proximity of the nucleotide binding domains of the P-glycoprotein multidrug transporter to the membrane surface: a resonance energy transfer study. Liu R, Sharom FJ. Biochemistry; 1998 May 05; 37(18):6503-12. PubMed ID: 9572868 [Abstract] [Full Text] [Related]
12. Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying crosslinking data: insight into the mechanism of ligand migration and binding sites. Vandevuer S, Van Bambeke F, Tulkens PM, Prévost M. Proteins; 2006 May 15; 63(3):466-78. PubMed ID: 16463278 [Abstract] [Full Text] [Related]
13. P-glycoprotein: from genomics to mechanism. Ambudkar SV, Kimchi-Sarfaty C, Sauna ZE, Gottesman MM. Oncogene; 2003 Oct 20; 22(47):7468-85. PubMed ID: 14576852 [Abstract] [Full Text] [Related]
14. The power of the pump: mechanisms of action of P-glycoprotein (ABCB1). Ambudkar SV, Kim IW, Sauna ZE. Eur J Pharm Sci; 2006 Apr 20; 27(5):392-400. PubMed ID: 16352426 [Abstract] [Full Text] [Related]
16. Nucleotide binding, ATP hydrolysis, and mutation of the catalytic carboxylates of human P-glycoprotein cause distinct conformational changes in the transmembrane segments. Loo TW, Bartlett MC, Clarke DM. Biochemistry; 2007 Aug 14; 46(32):9328-36. PubMed ID: 17636884 [Abstract] [Full Text] [Related]
17. Fluorescence studies on the nucleotide binding domains of the P-glycoprotein multidrug transporter. Liu R, Sharom FJ. Biochemistry; 1997 Mar 11; 36(10):2836-43. PubMed ID: 9062112 [Abstract] [Full Text] [Related]
18. Drug binding and nucleotide hydrolyzability are essential requirements in the vanadate-induced inhibition of the human P-glycoprotein ATPase. Rao US. Biochemistry; 1998 Oct 20; 37(42):14981-8. PubMed ID: 9778376 [Abstract] [Full Text] [Related]