These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Journal Abstract Search
197 related items for PubMed ID: 11992639
1. Inhibition of tubulin polymerization by vitilevuamide, a bicyclic marine peptide, at a site distinct from colchicine, the vinca alkaloids, and dolastatin 10. Edler MC, Fernandez AM, Lassota P, Ireland CM, Barrows LR. Biochem Pharmacol; 2002 Feb 15; 63(4):707-15. PubMed ID: 11992639 [Abstract] [Full Text] [Related]
2. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain. Bai R, Pettit GR, Hamel E. Biochem Pharmacol; 1990 Jun 15; 39(12):1941-9. PubMed ID: 2353935 [Abstract] [Full Text] [Related]
3. Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity. Bai R, Roach MC, Jayaram SK, Barkoczy J, Pettit GR, Ludueña RF, Hamel E. Biochem Pharmacol; 1993 Apr 06; 45(7):1503-15. PubMed ID: 8471072 [Abstract] [Full Text] [Related]
5. Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules. Bai R, Friedman SJ, Pettit GR, Hamel E. Biochem Pharmacol; 1992 Jun 23; 43(12):2637-45. PubMed ID: 1632820 [Abstract] [Full Text] [Related]
6. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. Bai RL, Pettit GR, Hamel E. J Biol Chem; 1990 Oct 05; 265(28):17141-9. PubMed ID: 2211617 [Abstract] [Full Text] [Related]
7. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin. Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E. Mol Pharmacol; 1993 Oct 05; 44(4):757-66. PubMed ID: 8232226 [Abstract] [Full Text] [Related]
10. Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography. Cruz-Monserrate Z, Mullaney JT, Harran PG, Pettit GR, Hamel E. Eur J Biochem; 2003 Sep 05; 270(18):3822-8. PubMed ID: 12950266 [Abstract] [Full Text] [Related]
11. Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin. Cruz-Monserrate Z, Vervoort HC, Bai R, Newman DJ, Howell SB, Los G, Mullaney JT, Williams MD, Pettit GR, Fenical W, Hamel E. Mol Pharmacol; 2003 Jun 05; 63(6):1273-80. PubMed ID: 12761336 [Abstract] [Full Text] [Related]
12. Interactions of the sponge-derived antimitotic tripeptide hemiasterlin with tubulin: comparison with dolastatin 10 and cryptophycin 1. Bai R, Durso NA, Sackett DL, Hamel E. Biochemistry; 1999 Oct 26; 38(43):14302-10. PubMed ID: 10572005 [Abstract] [Full Text] [Related]
13. Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol. Pengsuparp T, Kingston DG, Neidigh KA, Cordell GA, Pezzuto JM. Chem Biol Interact; 1996 Aug 14; 101(2):103-14. PubMed ID: 8760392 [Abstract] [Full Text] [Related]
14. Cryptophycin 1 binds to tubulin at a site distinct from the colchicine binding site and at a site that may overlap the vinca binding site. Mooberry SL, Taoka CR, Busquets L. Cancer Lett; 1996 Oct 01; 107(1):53-7. PubMed ID: 8913266 [Abstract] [Full Text] [Related]
15. Interaction of cryptophycin 1 with tubulin and microtubules. Kerksiek K, Mejillano MR, Schwartz RE, Georg GI, Himes RH. FEBS Lett; 1995 Dec 11; 377(1):59-61. PubMed ID: 8543019 [Abstract] [Full Text] [Related]
16. Mechanism of action cryptophycin. Interaction with the Vinca alkaloid domain of tubulin. Smith CD, Zhang X. J Biol Chem; 1996 Mar 15; 271(11):6192-8. PubMed ID: 8626409 [Abstract] [Full Text] [Related]
17. Mechanism of action of E7010, an orally active sulfonamide antitumor agent: inhibition of mitosis by binding to the colchicine site of tubulin. Yoshimatsu K, Yamaguchi A, Yoshino H, Koyanagi N, Kitoh K. Cancer Res; 1997 Aug 01; 57(15):3208-13. PubMed ID: 9242451 [Abstract] [Full Text] [Related]
18. Interaction of marine toxin dolastatin 10 with porcine brain tubulin: competitive inhibition of rhizoxin and phomopsin A binding. Li Y, Kobayashi H, Hashimoto Y, Shirai R, Hirata A, Hayashi K, Hamada Y, Shioiri T, Iwasaki S. Chem Biol Interact; 1994 Dec 01; 93(3):175-83. PubMed ID: 7923438 [Abstract] [Full Text] [Related]
19. Natural products which interact with tubulin in the vinca domain: maytansine, rhizoxin, phomopsin A, dolastatins 10 and 15 and halichondrin B. Hamel E. Pharmacol Ther; 1992 Dec 01; 55(1):31-51. PubMed ID: 1287674 [Abstract] [Full Text] [Related]
20. Structure-activity studies with chiral isomers and with segments of the antimitotic marine peptide dolastatin 10. Bai RL, Pettit GR, Hamel E. Biochem Pharmacol; 1990 Oct 15; 40(8):1859-64. PubMed ID: 2242019 [Abstract] [Full Text] [Related] Page: [Next] [New Search]