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573 related items for PubMed ID: 11992650

  • 1. Regulation of cyclic AMP in rat pulmonary microvascular endothelial cells by rolipram-sensitive cyclic AMP phosphodiesterase (PDE4).
    Thompson WJ, Ashikaga T, Kelly JJ, Liu L, Zhu B, Vemavarapu L, Strada SJ.
    Biochem Pharmacol; 2002 Feb 15; 63(4):797-807. PubMed ID: 11992650
    [Abstract] [Full Text] [Related]

  • 2. Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells.
    Zhu B, Kelly J, Vemavarapu L, Thompson WJ, Strada SJ.
    Biochem Pharmacol; 2004 Aug 01; 68(3):479-91. PubMed ID: 15242814
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.
    Moon E, Lee R, Near R, Weintraub L, Wolda S, Lerner A.
    Clin Cancer Res; 2002 Feb 01; 8(2):589-95. PubMed ID: 11839681
    [Abstract] [Full Text] [Related]

  • 4. Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
    Suvarna NU, O'Donnell JM.
    J Pharmacol Exp Ther; 2002 Jul 01; 302(1):249-56. PubMed ID: 12065724
    [Abstract] [Full Text] [Related]

  • 5. Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process.
    Terry R, Cheung YF, Praestegaard M, Baillie GS, Huston E, Gall I, Adams DR, Houslay MD.
    Cell Signal; 2003 Oct 01; 15(10):955-71. PubMed ID: 12873709
    [Abstract] [Full Text] [Related]

  • 6. Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor.
    Barnard JW, Seibert AF, Prasad VR, Smart DA, Strada SJ, Taylor AE, Thompson WJ.
    J Appl Physiol (1985); 1994 Aug 01; 77(2):774-81. PubMed ID: 8002527
    [Abstract] [Full Text] [Related]

  • 7. Altered expression of cyclic nucleotide phosphodiesterase isozymes during culture of aortic endothelial cells.
    Ashikaga T, Strada SJ, Thompson WJ.
    Biochem Pharmacol; 1997 Nov 15; 54(10):1071-9. PubMed ID: 9464449
    [Abstract] [Full Text] [Related]

  • 8. Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.
    Michie AM, Lobban M, Müller T, Harnett MM, Houslay MD.
    Cell Signal; 1996 Feb 15; 8(2):97-110. PubMed ID: 8730511
    [Abstract] [Full Text] [Related]

  • 9. Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors.
    Kelly JJ, Barnes PJ, Giembycz MA.
    Biochem J; 1996 Sep 01; 318 ( Pt 2)(Pt 2):425-36. PubMed ID: 8809029
    [Abstract] [Full Text] [Related]

  • 10. Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway.
    Eckly AE, Lugnier C.
    Br J Pharmacol; 1994 Oct 01; 113(2):445-50. PubMed ID: 7834194
    [Abstract] [Full Text] [Related]

  • 11. Characterization of phosphodiesterase 4 in guinea-pig macrophages: multiple activities, association states and sensitivity to selective inhibitors.
    Kelly JJ, Barnes PJ, Giembycz MA.
    Br J Pharmacol; 1998 May 01; 124(1):129-40. PubMed ID: 9630352
    [Abstract] [Full Text] [Related]

  • 12. Identification of substrate specificity determinants in human cAMP-specific phosphodiesterase 4A by single-point mutagenesis.
    Richter W, Unciuleac L, Hermsdorf T, Kronbach T, Dettmer D.
    Cell Signal; 2001 Mar 01; 13(3):159-67. PubMed ID: 11282454
    [Abstract] [Full Text] [Related]

  • 13. Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats.
    Zhang HT, Huang Y, Mishler K, Roerig SC, O'Donnell JM.
    Psychopharmacology (Berl); 2005 Oct 01; 182(1):104-15. PubMed ID: 16010541
    [Abstract] [Full Text] [Related]

  • 14. Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase.
    McEwan DG, Brunton VG, Baillie GS, Leslie NR, Houslay MD, Frame MC.
    Cancer Res; 2007 Jun 01; 67(11):5248-57. PubMed ID: 17545604
    [Abstract] [Full Text] [Related]

  • 15. Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4.
    Blease K, Burke-Gaffney A, Hellewell PG.
    Br J Pharmacol; 1998 May 01; 124(1):229-37. PubMed ID: 9630364
    [Abstract] [Full Text] [Related]

  • 16. Pregnancy induces a modulation of the cAMP phosphodiesterase 4-conformers ratio in human myometrium: consequences for the utero-relaxant effect of PDE4-selective inhibitors.
    Méhats C, Tanguy G, Paris B, Robert B, Pernin N, Ferré F, Leroy MJ.
    J Pharmacol Exp Ther; 2000 Feb 01; 292(2):817-23. PubMed ID: 10640323
    [Abstract] [Full Text] [Related]

  • 17. Pig aortic endothelial-cell cyclic nucleotide phosphodiesterases. Use of phosphodiesterase inhibitors to evaluate their roles in regulating cyclic nucleotide levels in intact cells.
    Souness JE, Diocee BK, Martin W, Moodie SA.
    Biochem J; 1990 Feb 15; 266(1):127-32. PubMed ID: 2155604
    [Abstract] [Full Text] [Related]

  • 18. Type 4 cAMP phosphodiesterase (PDE4) inhibitors augment glucocorticoid-mediated apoptosis in B cell chronic lymphocytic leukemia (B-CLL) in the absence of exogenous adenylyl cyclase stimulation.
    Tiwari S, Dong H, Kim EJ, Weintraub L, Epstein PM, Lerner A.
    Biochem Pharmacol; 2005 Feb 01; 69(3):473-83. PubMed ID: 15652238
    [Abstract] [Full Text] [Related]

  • 19. The pharmacodynamic action of the cyclic AMP phosphodiesterase inhibitor rolipram on prolactin producing rat pituitary adenoma (GH4C1) cells.
    Gordeladze JO.
    Biosci Rep; 1990 Aug 01; 10(4):375-88. PubMed ID: 2174276
    [Abstract] [Full Text] [Related]

  • 20. Development of rolipram-sensitive, cyclic AMP phosphodiesterase (PDE4) in rat primary neuronal cultures.
    Ye Y, Jackson K, Houslay MD, Chandler LJ, O'Donnell JM.
    Brain Res Dev Brain Res; 2001 Sep 23; 130(1):115-21. PubMed ID: 11557100
    [Abstract] [Full Text] [Related]

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