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897 related items for PubMed ID: 11994439

  • 1. 4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function.
    Wen T, Bukczynski J, Watts TH.
    J Immunol; 2002 May 15; 168(10):4897-906. PubMed ID: 11994439
    [Abstract] [Full Text] [Related]

  • 2. 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy.
    Cannons JL, Lau P, Ghumman B, DeBenedette MA, Yagita H, Okumura K, Watts TH.
    J Immunol; 2001 Aug 01; 167(3):1313-24. PubMed ID: 11466348
    [Abstract] [Full Text] [Related]

  • 3. Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection.
    Bertram EM, Lau P, Watts TH.
    J Immunol; 2002 Apr 15; 168(8):3777-85. PubMed ID: 11937529
    [Abstract] [Full Text] [Related]

  • 4. 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses.
    Dawicki W, Bertram EM, Sharpe AH, Watts TH.
    J Immunol; 2004 Nov 15; 173(10):5944-51. PubMed ID: 15528328
    [Abstract] [Full Text] [Related]

  • 5. Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients.
    Blazar BR, Kwon BS, Panoskaltsis-Mortari A, Kwak KB, Peschon JJ, Taylor PA.
    J Immunol; 2001 Mar 01; 166(5):3174-83. PubMed ID: 11207270
    [Abstract] [Full Text] [Related]

  • 6. IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival.
    Pulle G, Vidric M, Watts TH.
    J Immunol; 2006 Mar 01; 176(5):2739-48. PubMed ID: 16493029
    [Abstract] [Full Text] [Related]

  • 7. A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo.
    Bertram EM, Dawicki W, Sedgmen B, Bramson JL, Lynch DH, Watts TH.
    J Immunol; 2004 Jan 15; 172(2):981-8. PubMed ID: 14707071
    [Abstract] [Full Text] [Related]

  • 8. 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses.
    Shuford WW, Klussman K, Tritchler DD, Loo DT, Chalupny J, Siadak AW, Brown TJ, Emswiler J, Raecho H, Larsen CP, Pearson TC, Ledbetter JA, Aruffo A, Mittler RS.
    J Exp Med; 1997 Jul 07; 186(1):47-55. PubMed ID: 9206996
    [Abstract] [Full Text] [Related]

  • 9. Murine CD8 lymphocyte expansion in vitro by artificial antigen-presenting cells expressing CD137L (4-1BBL) is superior to CD28, and CD137L expressed on neuroblastoma expands CD8 tumour-reactive effector cells in vivo.
    Yan X, Johnson BD, Orentas RJ.
    Immunology; 2004 May 07; 112(1):105-16. PubMed ID: 15096190
    [Abstract] [Full Text] [Related]

  • 10. CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand.
    Saoulli K, Lee SY, Cannons JL, Yeh WC, Santana A, Goldstein MD, Bangia N, DeBenedette MA, Mak TW, Choi Y, Watts TH.
    J Exp Med; 1998 Jun 01; 187(11):1849-62. PubMed ID: 9607925
    [Abstract] [Full Text] [Related]

  • 11. Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus.
    DeBenedette MA, Wen T, Bachmann MF, Ohashi PS, Barber BH, Stocking KL, Peschon JJ, Watts TH.
    J Immunol; 1999 Nov 01; 163(9):4833-41. PubMed ID: 10528184
    [Abstract] [Full Text] [Related]

  • 12. Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection.
    Shedlock DJ, Whitmire JK, Tan J, MacDonald AS, Ahmed R, Shen H.
    J Immunol; 2003 Feb 15; 170(4):2053-63. PubMed ID: 12574376
    [Abstract] [Full Text] [Related]

  • 13. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses.
    Tan JT, Whitmire JK, Ahmed R, Pearson TC, Larsen CP.
    J Immunol; 1999 Nov 01; 163(9):4859-68. PubMed ID: 10528187
    [Abstract] [Full Text] [Related]

  • 14. Expression and function of 4-1BB during CD4 versus CD8 T cell responses in vivo.
    Dawicki W, Watts TH.
    Eur J Immunol; 2004 Mar 01; 34(3):743-751. PubMed ID: 14991604
    [Abstract] [Full Text] [Related]

  • 15. [The role of costimulatory molecule 4-1BB and CD28 in activating of various T cell subsets from human peripheral blood].
    Wu JY, Qian F, Lu HZ, Wang W, Li BQ.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2004 Sep 01; 20(5):533-6. PubMed ID: 15367340
    [Abstract] [Full Text] [Related]

  • 16. Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration.
    Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S.
    Exp Mol Med; 2009 Dec 31; 41(12):896-911. PubMed ID: 19745604
    [Abstract] [Full Text] [Related]

  • 17. Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells.
    Futagawa T, Akiba H, Kodama T, Takeda K, Hosoda Y, Yagita H, Okumura K.
    Int Immunol; 2002 Mar 31; 14(3):275-86. PubMed ID: 11867564
    [Abstract] [Full Text] [Related]

  • 18. Differential clonal expansion of CD4 and CD8 T cells in response to 4-1BB ligation: contribution of 4-1BB during inflammatory responses.
    Takahashi C, Mittler RS, Vella AT.
    Immunol Lett; 2001 Apr 02; 76(3):183-91. PubMed ID: 11306146
    [Abstract] [Full Text] [Related]

  • 19. Role of 4-1BB (CD137) in the functional activation of cord blood CD28(-)CD8(+) T cells.
    Kim YJ, Brutkiewicz RR, Broxmeyer HE.
    Blood; 2002 Nov 01; 100(9):3253-60. PubMed ID: 12384425
    [Abstract] [Full Text] [Related]

  • 20. During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion.
    Hendriks J, Xiao Y, Rossen JW, van der Sluijs KF, Sugamura K, Ishii N, Borst J.
    J Immunol; 2005 Aug 01; 175(3):1665-76. PubMed ID: 16034107
    [Abstract] [Full Text] [Related]

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