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Journal Abstract Search


198 related items for PubMed ID: 12000756

  • 1. The cathepsin B of Toxoplasma gondii, toxopain-1, is critical for parasite invasion and rhoptry protein processing.
    Que X, Ngo H, Lawton J, Gray M, Liu Q, Engel J, Brinen L, Ghosh P, Joiner KA, Reed SL.
    J Biol Chem; 2002 Jul 12; 277(28):25791-7. PubMed ID: 12000756
    [Abstract] [Full Text] [Related]

  • 2. The cathepsin L of Toxoplasma gondii (TgCPL) and its endogenous macromolecular inhibitor, toxostatin.
    Huang R, Que X, Hirata K, Brinen LS, Lee JH, Hansell E, Engel J, Sajid M, Reed S.
    Mol Biochem Parasitol; 2009 Mar 12; 164(1):86-94. PubMed ID: 19111576
    [Abstract] [Full Text] [Related]

  • 3. TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase.
    Miller SA, Thathy V, Ajioka JW, Blackman MJ, Kim K.
    Mol Microbiol; 2003 Aug 12; 49(4):883-94. PubMed ID: 12890015
    [Abstract] [Full Text] [Related]

  • 4. A Member of the Ferlin Calcium Sensor Family Is Essential for Toxoplasma gondii Rhoptry Secretion.
    Coleman BI, Saha S, Sato S, Engelberg K, Ferguson DJP, Coppens I, Lodoen MB, Gubbels MJ.
    mBio; 2018 Oct 02; 9(5):. PubMed ID: 30279285
    [Abstract] [Full Text] [Related]

  • 5. A Toxoplasma palmitoyl acyl transferase and the palmitoylated armadillo repeat protein TgARO govern apical rhoptry tethering and reveal a critical role for the rhoptries in host cell invasion but not egress.
    Beck JR, Fung C, Straub KW, Coppens I, Vashisht AA, Wohlschlegel JA, Bradley PJ.
    PLoS Pathog; 2013 Feb 02; 9(2):e1003162. PubMed ID: 23408890
    [Abstract] [Full Text] [Related]

  • 6. Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl.
    Larson ET, Parussini F, Huynh MH, Giebel JD, Kelley AM, Zhang L, Bogyo M, Merritt EA, Carruthers VB.
    J Biol Chem; 2009 Sep 25; 284(39):26839-50. PubMed ID: 19596863
    [Abstract] [Full Text] [Related]

  • 7. A cathepsin C-like protease mediates the post-translation modification of Toxoplasma gondii secretory proteins for optimal invasion and egress.
    Thornton LB, Key M, Micchelli C, Stasic AJ, Kwain S, Floyd K, Moreno SNJ, Dominy BN, Whitehead DC, Dou Z.
    mBio; 2023 Aug 31; 14(4):e0017423. PubMed ID: 37326431
    [Abstract] [Full Text] [Related]

  • 8. The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm.
    Beckers CJ, Dubremetz JF, Mercereau-Puijalon O, Joiner KA.
    J Cell Biol; 1994 Nov 31; 127(4):947-61. PubMed ID: 7962077
    [Abstract] [Full Text] [Related]

  • 9. Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1.
    Hajagos BE, Turetzky JM, Peng ED, Cheng SJ, Ryan CM, Souda P, Whitelegge JP, Lebrun M, Dubremetz JF, Bradley PJ.
    Traffic; 2012 Feb 31; 13(2):292-304. PubMed ID: 22035499
    [Abstract] [Full Text] [Related]

  • 10. AP-1 in Toxoplasma gondii mediates biogenesis of the rhoptry secretory organelle from a post-Golgi compartment.
    Ngô HM, Yang M, Paprotka K, Pypaert M, Hoppe H, Joiner KA.
    J Biol Chem; 2003 Feb 14; 278(7):5343-52. PubMed ID: 12446678
    [Abstract] [Full Text] [Related]

  • 11. Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite.
    Cabrera A, Herrmann S, Warszta D, Santos JM, John Peter AT, Kono M, Debrouver S, Jacobs T, Spielmann T, Ungermann C, Soldati-Favre D, Gilberger TW.
    Traffic; 2012 Oct 14; 13(10):1335-50. PubMed ID: 22759070
    [Abstract] [Full Text] [Related]

  • 12. Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii.
    Lamarque MH, Papoin J, Finizio AL, Lentini G, Pfaff AW, Candolfi E, Dubremetz JF, Lebrun M.
    PLoS One; 2012 Oct 14; 7(3):e32457. PubMed ID: 22427839
    [Abstract] [Full Text] [Related]

  • 13. Cysteine and serine protease inhibitors block intracellular development and disrupt the secretory pathway of Toxoplasma gondii.
    Shaw MK, Roos DS, Tilney LG.
    Microbes Infect; 2002 Feb 14; 4(2):119-32. PubMed ID: 11880042
    [Abstract] [Full Text] [Related]

  • 14. The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells.
    Carey KL, Jongco AM, Kim K, Ward GE.
    Eukaryot Cell; 2004 Oct 14; 3(5):1320-30. PubMed ID: 15470260
    [Abstract] [Full Text] [Related]

  • 15. Processing of Toxoplasma ROP1 protein in nascent rhoptries.
    Soldati D, Lassen A, Dubremetz JF, Boothroyd JC.
    Mol Biochem Parasitol; 1998 Oct 30; 96(1-2):37-48. PubMed ID: 9851605
    [Abstract] [Full Text] [Related]

  • 16. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi.
    Lalmanach G, Mayer R, Serveau C, Scharfstein J, Gauthier F.
    Biochem J; 1996 Sep 01; 318 ( Pt 2)(Pt 2):395-9. PubMed ID: 8809025
    [Abstract] [Full Text] [Related]

  • 17. The Toxoplasma adhesive protein MIC2 is proteolytically processed at multiple sites by two parasite-derived proteases.
    Carruthers VB, Sherman GD, Sibley LD.
    J Biol Chem; 2000 May 12; 275(19):14346-53. PubMed ID: 10799515
    [Abstract] [Full Text] [Related]

  • 18. Cathepsin Cs are key for the intracellular survival of the protozoan parasite, Toxoplasma gondii.
    Que X, Engel JC, Ferguson D, Wunderlich A, Tomavo S, Reed SL.
    J Biol Chem; 2007 Feb 16; 282(7):4994-5003. PubMed ID: 17164247
    [Abstract] [Full Text] [Related]

  • 19. Identification of the pro-mature processing site of Toxoplasma ROP1 by mass spectrometry.
    Bradley PJ, Boothroyd JC.
    Mol Biochem Parasitol; 1999 May 15; 100(1):103-9. PubMed ID: 10376998
    [Abstract] [Full Text] [Related]

  • 20. A Glycosylphosphatidylinositol-Anchored Carbonic Anhydrase-Related Protein of Toxoplasma gondii Is Important for Rhoptry Biogenesis and Virulence.
    Chasen NM, Asady B, Lemgruber L, Vommaro RC, Kissinger JC, Coppens I, Moreno SNJ.
    mSphere; 2017 May 15; 2(3):. PubMed ID: 28529974
    [Abstract] [Full Text] [Related]


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