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180 related items for PubMed ID: 12006545
1. Overexpression of PTEN increases sensitivity to SN-38, an active metabolite of the topoisomerase I inhibitor irinotecan, in ovarian cancer cells. Saga Y, Mizukami H, Suzuki M, Kohno T, Urabe M, Ozawa K, Sato I. Clin Cancer Res; 2002 May; 8(5):1248-52. PubMed ID: 12006545 [Abstract] [Full Text] [Related]
2. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C. Cancer Res; 1999 Nov 15; 59(22):5808-14. PubMed ID: 10582703 [Abstract] [Full Text] [Related]
8. PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells. Choi Y, Zhang J, Murga C, Yu H, Koller E, Monia BP, Gutkind JS, Li W. Oncogene; 2002 Aug 08; 21(34):5289-300. PubMed ID: 12149650 [Abstract] [Full Text] [Related]
9. Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas. Kurose K, Zhou XP, Araki T, Cannistra SA, Maher ER, Eng C. Am J Pathol; 2001 Jun 08; 158(6):2097-106. PubMed ID: 11395387 [Abstract] [Full Text] [Related]
10. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells. St-Germain ME, Gagnon V, Mathieu I, Parent S, Asselin E. Int J Oncol; 2004 May 08; 24(5):1311-24. PubMed ID: 15067356 [Abstract] [Full Text] [Related]
11. [PTEN expression in endometrial cancer and the prognosis]. Kanamori Y, Uegaki K, Kigawa J, Terakawa N. Nihon Rinsho; 2004 Oct 08; 62 Suppl 10():406-9. PubMed ID: 15535277 [No Abstract] [Full Text] [Related]
12. Growth suppression activity of the PTEN tumor suppressor gene in human endometrial cancer cells. Lilja JF, Wu D, Reynolds RK, Lin J. Anticancer Res; 2001 Oct 08; 21(3B):1969-74. PubMed ID: 11497285 [Abstract] [Full Text] [Related]
13. Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779. Shi Y, Gera J, Hu L, Hsu JH, Bookstein R, Li W, Lichtenstein A. Cancer Res; 2002 Sep 01; 62(17):5027-34. PubMed ID: 12208757 [Abstract] [Full Text] [Related]
15. PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein. Paramio JM, Navarro M, Segrelles C, Gómez-Casero E, Jorcano JL. Oncogene; 1999 Dec 09; 18(52):7462-8. PubMed ID: 10602505 [Abstract] [Full Text] [Related]
16. In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin. Tanaka M, Grossman HB. Gene Ther; 2003 Sep 09; 10(19):1636-42. PubMed ID: 12923562 [Abstract] [Full Text] [Related]
17. PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1. Bruni P, Boccia A, Baldassarre G, Trapasso F, Santoro M, Chiappetta G, Fusco A, Viglietto G. Oncogene; 2000 Jun 29; 19(28):3146-55. PubMed ID: 10918569 [Abstract] [Full Text] [Related]
18. PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway. Wan X, Yokoyama Y, Shinohara A, Takahashi Y, Tamaya T. Cell Death Differ; 2002 Apr 29; 9(4):414-20. PubMed ID: 11965494 [Abstract] [Full Text] [Related]
19. Pten signaling in gliomas. Knobbe CB, Merlo A, Reifenberger G. Neuro Oncol; 2002 Jul 29; 4(3):196-211. PubMed ID: 12084351 [Abstract] [Full Text] [Related]
20. Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner. Yan X, Fraser M, Qiu Q, Tsang BK. Gynecol Oncol; 2006 Aug 29; 102(2):348-55. PubMed ID: 16545436 [Abstract] [Full Text] [Related] Page: [Next] [New Search]