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1241 related items for PubMed ID: 12006974

  • 1. T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells.
    Afkarian M, Sedy JR, Yang J, Jacobson NG, Cereb N, Yang SY, Murphy TL, Murphy KM.
    Nat Immunol; 2002 Jun; 3(6):549-57. PubMed ID: 12006974
    [Abstract] [Full Text] [Related]

  • 2. Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.
    Schulz EG, Mariani L, Radbruch A, Höfer T.
    Immunity; 2009 May; 30(5):673-83. PubMed ID: 19409816
    [Abstract] [Full Text] [Related]

  • 3. Polarization of IL-4- and IFN-gamma-producing CD4+ T cells following activation of naive CD4+ T cells.
    Nakamura T, Kamogawa Y, Bottomly K, Flavell RA.
    J Immunol; 1997 Feb 01; 158(3):1085-94. PubMed ID: 9013946
    [Abstract] [Full Text] [Related]

  • 4. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription.
    Usui T, Preiss JC, Kanno Y, Yao ZJ, Bream JH, O'Shea JJ, Strober W.
    J Exp Med; 2006 Mar 20; 203(3):755-66. PubMed ID: 16520391
    [Abstract] [Full Text] [Related]

  • 5. Interleukin-12 and -18 levels in peritoneal dialysate effluent correlate with the outcome of peritonitis in patients undergoing peritoneal dialysis: implications for the Type I/Type II T-cell immune response.
    Wang HH, Lin CY.
    Am J Kidney Dis; 2005 Aug 20; 46(2):328-38. PubMed ID: 16112053
    [Abstract] [Full Text] [Related]

  • 6. IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells.
    Ylikoski E, Lund R, Kyläniemi M, Filén S, Kilpeläinen M, Savolainen J, Lahesmaa R.
    Eur J Immunol; 2005 Nov 20; 35(11):3297-306. PubMed ID: 16220539
    [Abstract] [Full Text] [Related]

  • 7. Frontline: absence of functional STAT4 activation despite detectable tyrosine phosphorylation induced by murine IFN-alpha.
    Berenson LS, Farrar JD, Murphy TL, Murphy KM.
    Eur J Immunol; 2004 Sep 20; 34(9):2365-74. PubMed ID: 15307169
    [Abstract] [Full Text] [Related]

  • 8. Factors effecting the Th2-like immune response after gamma-irradiation: low production of IL-12 heterodimer in antigen-presenting cells and small expression of the IL-12 receptor in T cells.
    Park HR, Jo SK, Paik SG.
    Int J Radiat Biol; 2005 Mar 20; 81(3):221-31. PubMed ID: 16019931
    [Abstract] [Full Text] [Related]

  • 9. Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation.
    Letimier FA, Passini N, Gasparian S, Bianchi E, Rogge L.
    EMBO J; 2007 Mar 07; 26(5):1292-302. PubMed ID: 17304212
    [Abstract] [Full Text] [Related]

  • 10. Instruction of naive CD4+ T-cell fate to T-bet expression and T helper 1 development: roles of T-cell receptor-mediated signals.
    Ariga H, Shimohakamada Y, Nakada M, Tokunaga T, Kikuchi T, Kariyone A, Tamura T, Takatsu K.
    Immunology; 2007 Oct 07; 122(2):210-21. PubMed ID: 17490433
    [Abstract] [Full Text] [Related]

  • 11. T-box 21 transcription factor is responsible for distorted T(H)2 differentiation in human peripheral CD4+ T cells.
    Kaminuma O, Kitamura F, Miyatake S, Yamaoka K, Miyoshi H, Inokuma S, Tatsumi H, Nemoto S, Kitamura N, Mori A, Hiroi T.
    J Allergy Clin Immunol; 2009 Apr 07; 123(4):813-23.e3. PubMed ID: 19348920
    [Abstract] [Full Text] [Related]

  • 12. CD28 costimulation is required not only to induce IL-12 receptor but also to render janus kinases/STAT4 responsive to IL-12 stimulation in TCR-triggered T cells.
    Park WR, Park CS, Tomura M, Ahn HJ, Nakahira Y, Iwasaki M, Gao P, Abe R, Hamaoka T, Fujiwara H.
    Eur J Immunol; 2001 May 07; 31(5):1456-64. PubMed ID: 11465102
    [Abstract] [Full Text] [Related]

  • 13. Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities.
    Lametschwandtner G, Biedermann T, Schwärzler C, Günther C, Kund J, Fassl S, Hinteregger S, Carballido-Perrig N, Szabo SJ, Glimcher LH, Carballido JM.
    J Allergy Clin Immunol; 2004 May 07; 113(5):987-94. PubMed ID: 15131585
    [Abstract] [Full Text] [Related]

  • 14. The direct effect of IL-12 on tumor cells: IL-12 acts directly on tumor cells to activate NF-kappaB and enhance IFN-gamma-mediated STAT1 phosphorylation.
    Su W, Ito T, Oyama T, Kitagawa T, Yamori T, Fujiwara H, Matsuda H.
    Biochem Biophys Res Commun; 2001 Jan 19; 280(2):503-12. PubMed ID: 11162546
    [Abstract] [Full Text] [Related]

  • 15. CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells.
    Liu N, Ohnishi N, Ni L, Akira S, Bacon KB.
    Nat Immunol; 2003 Jul 19; 4(7):687-93. PubMed ID: 12766768
    [Abstract] [Full Text] [Related]

  • 16. Activation of STAT proteins and cytokine genes in human Th1 and Th2 cells generated in the absence of IL-12 and IL-4.
    Moriggl R, Kristofic C, Kinzel B, Volarevic S, Groner B, Brinkmann V.
    J Immunol; 1998 Apr 01; 160(7):3385-92. PubMed ID: 9531298
    [Abstract] [Full Text] [Related]

  • 17. IL-28A is a key regulator of T-cell-mediated liver injury via the T-box transcription factor T-bet.
    Siebler J, Wirtz S, Weigmann B, Atreya I, Schmitt E, Kreft A, Galle PR, Neurath MF.
    Gastroenterology; 2007 Jan 01; 132(1):358-71. PubMed ID: 17241885
    [Abstract] [Full Text] [Related]

  • 18. IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12.
    Matikainen S, Paananen A, Miettinen M, Kurimoto M, Timonen T, Julkunen I, Sareneva T.
    Eur J Immunol; 2001 Jul 01; 31(7):2236-45. PubMed ID: 11449378
    [Abstract] [Full Text] [Related]

  • 19. Intestinal irradiation and fibrosis in a Th1-deficient environment.
    Linard C, Billiard F, Benderitter M.
    Int J Radiat Oncol Biol Phys; 2012 Sep 01; 84(1):266-73. PubMed ID: 22336200
    [Abstract] [Full Text] [Related]

  • 20. Immune-mediated neuroprotection of axotomized mouse facial motoneurons is dependent on the IL-4/STAT6 signaling pathway in CD4(+) T cells.
    Deboy CA, Xin J, Byram SC, Serpe CJ, Sanders VM, Jones KJ.
    Exp Neurol; 2006 Sep 01; 201(1):212-24. PubMed ID: 16806176
    [Abstract] [Full Text] [Related]

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