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Journal Abstract Search

146 related items for PubMed ID: 12031872

  • 1. Synthesis, biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high affinity for the 5-HT(1A) receptor and the alpha1-adrenergic receptor.
    Heimbold I, Drews A, Kretzschmar M, Varnäs K, Hall H, Halldin C, Syhre R, Kraus W, Pietzsch HJ, Seifert S, Brust P, Johannsen B.
    Nucl Med Biol; 2002 May; 29(4):375-87. PubMed ID: 12031872
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  • 3. A novel technetium-99m radioligand for the 5-HT(1A) receptor derived from desmethyl-WAY-100635 (DWAY).
    Heimbold I, Drews A, Syhre R, Kretzschmar M, Pietzsch HJ, Johannsen B.
    Eur J Nucl Med Mol Imaging; 2002 Jan; 29(1):82-7. PubMed ID: 11807611
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  • 7. trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
    Perrone R, Berardi F, Colabufo NA, Leopoldo M, Lacivita E, Tortorella V, Leonardi A, Poggesi E, Testa R.
    J Med Chem; 2001 Dec 06; 44(25):4431-42. PubMed ID: 11728188
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  • 8. Synthesis and structure-activity relationships of a new model of arylpiperazines. Study of the 5-HT(1a)/alpha(1)-adrenergic receptor affinity by classical hansch analysis, artificial neural networks, and computational simulation of ligand recognition.
    López-Rodríguez ML, Morcillo MJ, Fernández E, Rosado ML, Pardo L, Schaper K.
    J Med Chem; 2001 Jan 18; 44(2):198-207. PubMed ID: 11170629
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  • 9. In vivo characterization of p-[(18)F]MPPF, a fluoro analog of WAY-100635 for visualization of 5-HT(1a) receptors.
    Ginovart N, Hassoun W, Le Bars D, Weissmann D, Leviel V.
    Synapse; 2000 Mar 01; 35(3):192-200. PubMed ID: 10657026
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  • 10. Synthesis and structure-activity relationships of a new model of arylpiperazines. 5. Study of the physicochemical influence of the pharmacophore on 5-HT(1a)/alpha(1)-adrenergic receptor affinity: synthesis of a new derivative with mixed 5-HT(1a)/d(2) antagonist properties.
    López-Rodríguez ML, Morcillo MJ, Fernández E, Porras E, Orensanz L, Beneytez ME, Manzanares J, Fuentes JA.
    J Med Chem; 2001 Jan 18; 44(2):186-97. PubMed ID: 11170628
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  • 18. Novel mixed ligand technetium complexes as 5-HT1A receptor imaging agents.
    León A, Rey A, Mallo L, Pirmettis I, Papadopoulos M, León E, Pagano M, Manta E, Incerti M, Raptopoulou C, Terzis A, Chiotellis E.
    Nucl Med Biol; 2002 Feb 18; 29(2):217-26. PubMed ID: 11823127
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  • 19. WAY-100635 antagonist-induced plasticity of 5-HT receptors: regulatory differences between a stable cell line and an in vivo native system.
    Khawaja XZ, Smith DL, Nawoschik SP, Zhang J, Dunlop J, Dilks DW, Olsen M, Schechter LE.
    J Neurochem; 2006 Jul 18; 98(1):134-45. PubMed ID: 16805803
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  • 20. Improvement in the selectivity and metabolic stability of the serotonin 5-HT(1A) ligand, S 15535: a series of cis- and trans-2-(arylcycloalkylamine) 1-indanols.
    Peglion JL, Goument B, Despaux N, Charlot V, Giraud H, Nisole C, Newman-Tancredi A, Dekeyne A, Bertrand M, Genissel P, Millan MJ.
    J Med Chem; 2002 Jan 03; 45(1):165-76. PubMed ID: 11754589
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