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338 related items for PubMed ID: 12031952

  • 1. Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes.
    Matsumoto M, Ogawa W, Teshigawara K, Inoue H, Miyake K, Sakaue H, Kasuga M.
    Diabetes; 2002 Jun; 51(6):1672-80. PubMed ID: 12031952
    [Abstract] [Full Text] [Related]

  • 2. Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes.
    Ribaux PG, Iynedjian PB.
    Biochem J; 2003 Dec 15; 376(Pt 3):697-705. PubMed ID: 14505487
    [Abstract] [Full Text] [Related]

  • 3. Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation.
    Mur C, Arribas M, Benito M, Valverde AM.
    Endocrinology; 2003 Feb 15; 144(2):581-93. PubMed ID: 12538620
    [Abstract] [Full Text] [Related]

  • 4. Role of IRS-3 in the insulin signaling of IRS-1-deficient brown adipocytes.
    Arribas M, Valverde AM, Benito M.
    J Biol Chem; 2003 Nov 14; 278(46):45189-99. PubMed ID: 12944402
    [Abstract] [Full Text] [Related]

  • 5. Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.
    Laviola L, Belsanti G, Davalli AM, Napoli R, Perrini S, Weir GC, Giorgino R, Giorgino F.
    Diabetes; 2001 Dec 14; 50(12):2709-20. PubMed ID: 11723053
    [Abstract] [Full Text] [Related]

  • 6. Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes.
    Fasshauer M, Klein J, Kriauciunas KM, Ueki K, Benito M, Kahn CR.
    Mol Cell Biol; 2001 Jan 14; 21(1):319-29. PubMed ID: 11113206
    [Abstract] [Full Text] [Related]

  • 7. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4640-5. PubMed ID: 11287630
    [Abstract] [Full Text] [Related]

  • 8. Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes.
    Valverde AM, Burks DJ, Fabregat I, Fisher TL, Carretero J, White MF, Benito M.
    Diabetes; 2003 Sep 10; 52(9):2239-48. PubMed ID: 12941762
    [Abstract] [Full Text] [Related]

  • 9. Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance.
    Lima MH, Ueno M, Thirone AC, Rocha EM, Carvalho CR, Saad MJ.
    Endocrine; 2002 Jun 10; 18(1):1-12. PubMed ID: 12166618
    [Abstract] [Full Text] [Related]

  • 10. IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes.
    Valverde AM, Fabregat I, Burks DJ, White MF, Benito M.
    Hepatology; 2004 Dec 10; 40(6):1285-94. PubMed ID: 15565601
    [Abstract] [Full Text] [Related]

  • 11. Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.
    Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB.
    Diabetes; 1999 Feb 10; 48(2):310-20. PubMed ID: 10334307
    [Abstract] [Full Text] [Related]

  • 12. Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
    Uddin S, Majchrzak B, Wang PC, Modi S, Khan MK, Fish EN, Platanias LC.
    Biochem Biophys Res Commun; 2000 Apr 02; 270(1):158-62. PubMed ID: 10733921
    [Abstract] [Full Text] [Related]

  • 13. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes.
    Foretz M, Guichard C, Ferré P, Foufelle F.
    Proc Natl Acad Sci U S A; 1999 Oct 26; 96(22):12737-42. PubMed ID: 10535992
    [Abstract] [Full Text] [Related]

  • 14. Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway.
    Hirashima Y, Tsuruzoe K, Kodama S, Igata M, Toyonaga T, Ueki K, Kahn CR, Araki E.
    J Endocrinol; 2003 Nov 26; 179(2):253-66. PubMed ID: 14596677
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation.
    Borradaile NM, de Dreu LE, Huff MW.
    Diabetes; 2003 Oct 26; 52(10):2554-61. PubMed ID: 14514640
    [Abstract] [Full Text] [Related]

  • 16. Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes.
    Rojas FA, Hirata AE, Saad MJ.
    Mol Cell Endocrinol; 2001 Oct 25; 183(1-2):63-9. PubMed ID: 11604226
    [Abstract] [Full Text] [Related]

  • 17. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.
    Yellaturu CR, Deng X, Cagen LM, Wilcox HG, Mansbach CM, Siddiqi SA, Park EA, Raghow R, Elam MB.
    J Biol Chem; 2009 Mar 20; 284(12):7518-32. PubMed ID: 19158095
    [Abstract] [Full Text] [Related]

  • 18. Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.
    Azzout-Marniche D, Bécard D, Guichard C, Foretz M, Ferré P, Foufelle F.
    Biochem J; 2000 Sep 01; 350 Pt 2(Pt 2):389-93. PubMed ID: 10947952
    [Abstract] [Full Text] [Related]

  • 19. Interaction of insulin receptor substrate-1 (IRS-1) with phosphatidylinositol 3-kinase: effect of substitution of serine for alanine in potential IRS-1 serine phosphorylation sites.
    Delahaye L, Mothe-Satney I, Myers MG, White MF, Van Obberghen E.
    Endocrinology; 1998 Dec 01; 139(12):4911-9. PubMed ID: 9832428
    [Abstract] [Full Text] [Related]

  • 20. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C, Welsh M.
    Mol Med; 2002 Nov 01; 8(11):705-13. PubMed ID: 12520087
    [Abstract] [Full Text] [Related]

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