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111 related items for PubMed ID: 12034568
1. PDE4 inhibitors attenuate fibroblast chemotaxis and contraction of native collagen gels. Kohyama T, Liu X, Wen FQ, Zhu YK, Wang H, Kim HJ, Takizawa H, Cieslinski LB, Barnette MS, Rennard SI. Am J Respir Cell Mol Biol; 2002 Jun; 26(6):694-701. PubMed ID: 12034568 [Abstract] [Full Text] [Related]
2. PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts. Togo S, Liu X, Wang X, Sugiura H, Kamio K, Kawasaki S, Kobayashi T, Ertl RF, Ahn Y, Holz O, Magnussen H, Fredriksson K, Skold CM, Rennard SI. Am J Physiol Lung Cell Mol Physiol; 2009 Jun; 296(6):L959-69. PubMed ID: 19304913 [Abstract] [Full Text] [Related]
3. Phosphodiesterase 4 inhibitor cilomilast inhibits fibroblast-mediated collagen gel degradation induced by tumor necrosis factor-alpha and neutrophil elastase. Kohyama T, Liu X, Zhu YK, Wen FQ, Wang HJ, Fang Q, Kobayashi T, Rennard SI. Am J Respir Cell Mol Biol; 2002 Oct; 27(4):487-94. PubMed ID: 12356583 [Abstract] [Full Text] [Related]
4. Modulation of matrix metalloproteinase production from human lung fibroblasts by type 4 phosphodiesterase inhibitors. Martin-Chouly CA, Astier A, Jacob C, Pruniaux MP, Bertrand C, Lagente V. Life Sci; 2004 Jul 02; 75(7):823-40. PubMed ID: 15183075 [Abstract] [Full Text] [Related]
5. Cytokine inhibition of fibroblast-induced gel contraction is mediated by PGE(2) and NO acting through separate parallel pathways. Zhu YK, Liu XD, Sköld MC, Umino T, Wang H, Romberger DJ, Spurzem JR, Kohyama T, Wen FQ, Rennard SI. Am J Respir Cell Mol Biol; 2001 Aug 02; 25(2):245-53. PubMed ID: 11509336 [Abstract] [Full Text] [Related]
7. Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia. Moon E, Lee R, Near R, Weintraub L, Wolda S, Lerner A. Clin Cancer Res; 2002 Feb 02; 8(2):589-95. PubMed ID: 11839681 [Abstract] [Full Text] [Related]
8. In vitro pharmacology of the novel phosphodiesterase type 4 inhibitor, CP-80633. Cohan VL, Showell HJ, Fisher DA, Pazoles CJ, Watson JW, Turner CR, Cheng JB. J Pharmacol Exp Ther; 1996 Sep 02; 278(3):1356-61. PubMed ID: 8819523 [Abstract] [Full Text] [Related]
11. PGE 2 desensitizes β -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4. Fang Q, Ma Y, Wang J, Michalski J, Rennard SI, Liu X. Mediators Inflamm; 2013 Sep 02; 2013():145197. PubMed ID: 24227907 [Abstract] [Full Text] [Related]
12. Differential regulation of human antigen-specific Th1 and Th2 lymphocyte responses by isozyme selective cyclic nucleotide phosphodiesterase inhibitors. Essayan DM, Kagey-Sobotka A, Lichtenstein LM, Huang SK. J Pharmacol Exp Ther; 1997 Jul 02; 282(1):505-12. PubMed ID: 9223593 [Abstract] [Full Text] [Related]
13. Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4. Blease K, Burke-Gaffney A, Hellewell PG. Br J Pharmacol; 1998 May 02; 124(1):229-37. PubMed ID: 9630364 [Abstract] [Full Text] [Related]
14. Airway relaxant and anti-inflammatory properties of a PDE4 inhibitor with low affinity for the high-affinity rolipram binding site. Martin C, Göggel R, Dal Piaz V, Vergelli C, Giovannoni P, Ernst M, Uhlig S. Naunyn Schmiedebergs Arch Pharmacol; 2002 Apr 02; 365(4):284-9. PubMed ID: 11919652 [Abstract] [Full Text] [Related]
15. Modulation of spasmogen-stimulated Ins(1,4,5)P3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle. Challiss RA, Adams D, Mistry R, Nicholson CD. Br J Pharmacol; 1998 May 02; 124(1):47-54. PubMed ID: 9630342 [Abstract] [Full Text] [Related]
17. PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries. Santos-Silva AJ, Cairrão E, Morgado M, Alvarez E, Verde I. Eur J Pharmacol; 2008 Mar 17; 582(1-3):102-9. PubMed ID: 18234184 [Abstract] [Full Text] [Related]
19. Pregnancy induces a modulation of the cAMP phosphodiesterase 4-conformers ratio in human myometrium: consequences for the utero-relaxant effect of PDE4-selective inhibitors. Méhats C, Tanguy G, Paris B, Robert B, Pernin N, Ferré F, Leroy MJ. J Pharmacol Exp Ther; 2000 Feb 17; 292(2):817-23. PubMed ID: 10640323 [Abstract] [Full Text] [Related]