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327 related items for PubMed ID: 12036950

  • 1. Human papillomavirus E6-induced degradation of E6TP1 is mediated by E6AP ubiquitin ligase.
    Gao Q, Kumar A, Singh L, Huibregtse JM, Beaudenon S, Srinivasan S, Wazer DE, Band H, Band V.
    Cancer Res; 2002 Jun 01; 62(11):3315-21. PubMed ID: 12036950
    [Abstract] [Full Text] [Related]

  • 2. Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities.
    Kehmeier E, Rühl H, Voland B, Stöppler MC, Androphy E, Stöppler H.
    Virology; 2002 Jul 20; 299(1):72-87. PubMed ID: 12167343
    [Abstract] [Full Text] [Related]

  • 3. Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase.
    Kao WH, Beaudenon SL, Talis AL, Huibregtse JM, Howley PM.
    J Virol; 2000 Jul 20; 74(14):6408-17. PubMed ID: 10864652
    [Abstract] [Full Text] [Related]

  • 4. Human papillomavirus type 16 E6-induced degradation of E6TP1 correlates with its ability to immortalize human mammary epithelial cells.
    Gao Q, Singh L, Kumar A, Srinivasan S, Wazer DE, Band V.
    J Virol; 2001 May 20; 75(9):4459-66. PubMed ID: 11287601
    [Abstract] [Full Text] [Related]

  • 5. Involvement of a cellular ubiquitin-protein ligase E6AP in the ubiquitin-mediated degradation of extensive substrates of high-risk human papillomavirus E6.
    Matsumoto Y, Nakagawa S, Yano T, Takizawa S, Nagasaka K, Nakagawa K, Minaguchi T, Wada O, Ooishi H, Matsumoto K, Yasugi T, Kanda T, Huibregtse JM, Taketani Y.
    J Med Virol; 2006 Apr 20; 78(4):501-7. PubMed ID: 16482544
    [Abstract] [Full Text] [Related]

  • 6. E3 ubiquitin ligase E6AP-mediated TSC2 turnover in the presence and absence of HPV16 E6.
    Zheng L, Ding H, Lu Z, Li Y, Pan Y, Ning T, Ke Y.
    Genes Cells; 2008 Mar 20; 13(3):285-94. PubMed ID: 18298802
    [Abstract] [Full Text] [Related]

  • 7. The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation.
    Gao Q, Srinivasan S, Boyer SN, Wazer DE, Band V.
    Mol Cell Biol; 1999 Jan 20; 19(1):733-44. PubMed ID: 9858596
    [Abstract] [Full Text] [Related]

  • 8. Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase.
    Nakagawa S, Huibregtse JM.
    Mol Cell Biol; 2000 Nov 20; 20(21):8244-53. PubMed ID: 11027293
    [Abstract] [Full Text] [Related]

  • 9. The stability of the human papillomavirus E6 oncoprotein is E6AP dependent.
    Tomaić V, Pim D, Banks L.
    Virology; 2009 Oct 10; 393(1):7-10. PubMed ID: 19700180
    [Abstract] [Full Text] [Related]

  • 10. The high-risk human papillomavirus type 16 E6 counters the GAP function of E6TP1 toward small Rap G proteins.
    Singh L, Gao Q, Kumar A, Gotoh T, Wazer DE, Band H, Feig LA, Band V.
    J Virol; 2003 Jan 10; 77(2):1614-20. PubMed ID: 12502878
    [Abstract] [Full Text] [Related]

  • 11. Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.
    Poirson J, Biquand E, Straub ML, Cassonnet P, Nominé Y, Jones L, van der Werf S, Travé G, Zanier K, Jacob Y, Demeret C, Masson M.
    FEBS J; 2017 Oct 10; 284(19):3171-3201. PubMed ID: 28786561
    [Abstract] [Full Text] [Related]

  • 12. Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
    Martinez-Zapien D, Ruiz FX, Poirson J, Mitschler A, Ramirez J, Forster A, Cousido-Siah A, Masson M, Vande Pol S, Podjarny A, Travé G, Zanier K.
    Nature; 2016 Jan 28; 529(7587):541-5. PubMed ID: 26789255
    [Abstract] [Full Text] [Related]

  • 13. Human papillomavirus type 16 E6 protein interacts with cystic fibrosis transmembrane regulator-associated ligand and promotes E6-associated protein-mediated ubiquitination and proteasomal degradation.
    Jeong KW, Kim HZ, Kim S, Kim YS, Choe J.
    Oncogene; 2007 Jan 25; 26(4):487-99. PubMed ID: 16878151
    [Abstract] [Full Text] [Related]

  • 14. Identification of E6AP-independent degradation targets of HPV E6.
    Vats A, Thatte J, Banks L.
    J Gen Virol; 2019 Dec 25; 100(12):1674-1679. PubMed ID: 31609195
    [Abstract] [Full Text] [Related]

  • 15. The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.
    Talis AL, Huibregtse JM, Howley PM.
    J Biol Chem; 1998 Mar 13; 273(11):6439-45. PubMed ID: 9497376
    [Abstract] [Full Text] [Related]

  • 16. Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle.
    Lee C, Wooldridge TR, Laimins LA.
    Virology; 2007 Feb 05; 358(1):201-10. PubMed ID: 16999984
    [Abstract] [Full Text] [Related]

  • 17. Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells.
    Wang J, Sampath A, Raychaudhuri P, Bagchi S.
    Oncogene; 2001 Aug 02; 20(34):4740-9. PubMed ID: 11498796
    [Abstract] [Full Text] [Related]

  • 18. Kinetic analysis of the interactions of human papillomavirus E6 oncoproteins with the ubiquitin ligase E6AP using surface plasmon resonance.
    Zanier K, Charbonnier S, Baltzinger M, Nominé Y, Altschuh D, Travé G.
    J Mol Biol; 2005 Jun 03; 349(2):401-12. PubMed ID: 15890204
    [Abstract] [Full Text] [Related]

  • 19. A ubiquitin variant-based affinity approach selectively identifies substrates of the ubiquitin ligase E6AP in complex with HPV-11 E6 or HPV-16 E6.
    Ebner FA, Sailer C, Eichbichler D, Jansen J, Sladewska-Marquardt A, Stengel F, Scheffner M.
    J Biol Chem; 2020 Oct 30; 295(44):15070-15082. PubMed ID: 32855237
    [Abstract] [Full Text] [Related]

  • 20. The E6AP ubiquitin ligase is required for transactivation of the hTERT promoter by the human papillomavirus E6 oncoprotein.
    Liu X, Yuan H, Fu B, Disbrow GL, Apolinario T, Tomaic V, Kelley ML, Baker CC, Huibregtse J, Schlegel R.
    J Biol Chem; 2005 Mar 18; 280(11):10807-16. PubMed ID: 15655249
    [Abstract] [Full Text] [Related]

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