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282 related items for PubMed ID: 12039975

  • 1. Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation.
    Li JH, Zhu HJ, Huang XR, Lai KN, Johnson RJ, Lan HY.
    J Am Soc Nephrol; 2002 Jun; 13(6):1464-72. PubMed ID: 12039975
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model.
    Lan HY, Mu W, Tomita N, Huang XR, Li JH, Zhu HJ, Morishita R, Johnson RJ.
    J Am Soc Nephrol; 2003 Jun; 14(6):1535-48. PubMed ID: 12761254
    [Abstract] [Full Text] [Related]

  • 3. Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.
    Hou CC, Wang W, Huang XR, Fu P, Chen TH, Sheikh-Hamad D, Lan HY.
    Am J Pathol; 2005 Mar; 166(3):761-71. PubMed ID: 15743788
    [Abstract] [Full Text] [Related]

  • 4. Astragaloside IV inhibits renal tubulointerstitial fibrosis by blocking TGF-β/Smad signaling pathway in vivo and in vitro.
    Wang L, Chi YF, Yuan ZT, Zhou WC, Yin PH, Zhang XM, Peng W, Cai H.
    Exp Biol Med (Maywood); 2014 Oct; 239(10):1310-24. PubMed ID: 24879422
    [Abstract] [Full Text] [Related]

  • 5. Smad7 blocks transforming growth factor-β1-induced gingival fibroblast-myofibroblast transition via inhibitory regulation of Smad2 and connective tissue growth factor.
    Sobral LM, Montan PF, Zecchin KG, Martelli-Junior H, Vargas PA, Graner E, Coletta RD.
    J Periodontol; 2011 Apr; 82(4):642-51. PubMed ID: 21054221
    [Abstract] [Full Text] [Related]

  • 6. Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.
    Yang F, Chung AC, Huang XR, Lan HY.
    Hypertension; 2009 Oct; 54(4):877-84. PubMed ID: 19667256
    [Abstract] [Full Text] [Related]

  • 7. Role of TGF-beta signaling in extracellular matrix production under high glucose conditions.
    Li JH, Huang XR, Zhu HJ, Johnson R, Lan HY.
    Kidney Int; 2003 Jun; 63(6):2010-9. PubMed ID: 12753288
    [Abstract] [Full Text] [Related]

  • 8. TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways.
    Nakagawa T, Li JH, Garcia G, Mu W, Piek E, Böttinger EP, Chen Y, Zhu HJ, Kang DH, Schreiner GF, Lan HY, Johnson RJ.
    Kidney Int; 2004 Aug; 66(2):605-13. PubMed ID: 15253713
    [Abstract] [Full Text] [Related]

  • 9. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.
    Heeg MH, Koziolek MJ, Vasko R, Schaefer L, Sharma K, Müller GA, Strutz F.
    Kidney Int; 2005 Jul; 68(1):96-109. PubMed ID: 15954899
    [Abstract] [Full Text] [Related]

  • 10. Role of ERK1/2 and p38 mitogen-activated protein kinases in the regulation of thrombospondin-1 by TGF-beta1 in rat proximal tubular cells and mouse fibroblasts.
    Nakagawa T, Lan HY, Glushakova O, Zhu HJ, Kang DH, Schreiner GF, Böttinger EP, Johnson RJ, Sautin YY.
    J Am Soc Nephrol; 2005 Apr; 16(4):899-904. PubMed ID: 15716330
    [Abstract] [Full Text] [Related]

  • 11. Ectopic expression of Smad7 inhibits transforming growth factor-beta responses in vascular smooth muscle cells.
    Kato S, Ueda S, Tamaki K, Fujii M, Miyazono K, ten Dijke P, Morimatsu M, Okuda S.
    Life Sci; 2001 Oct 19; 69(22):2641-52. PubMed ID: 11712667
    [Abstract] [Full Text] [Related]

  • 12. Transforming growth factor-beta and Smad signalling in kidney diseases.
    Wang W, Koka V, Lan HY.
    Nephrology (Carlton); 2005 Feb 19; 10(1):48-56. PubMed ID: 15705182
    [Abstract] [Full Text] [Related]

  • 13. Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein.
    Boyer Arnold N, Korc M.
    J Biol Chem; 2005 Jun 10; 280(23):21858-66. PubMed ID: 15811853
    [Abstract] [Full Text] [Related]

  • 14. Bardoxolone ameliorates TGF-β1-associated renal fibrosis through Nrf2/Smad7 elevation.
    Song MK, Lee JH, Ryoo IG, Lee SH, Ku SK, Kwak MK.
    Free Radic Biol Med; 2019 Jul 10; 138():33-42. PubMed ID: 31059771
    [Abstract] [Full Text] [Related]

  • 15. Ultraviolet irradiation blocks cellular responses to transforming growth factor-beta by down-regulating its type-II receptor and inducing Smad7.
    Quan T, He T, Voorhees JJ, Fisher GJ.
    J Biol Chem; 2001 Jul 13; 276(28):26349-56. PubMed ID: 11320083
    [Abstract] [Full Text] [Related]

  • 16. WNT/β-catenin signal inhibitor IC-2-derived small-molecule compounds suppress TGF-β1-induced fibrogenic response of renal epithelial cells by inhibiting SMAD2/3 signalling.
    Hoi S, Tsuchiya H, Itaba N, Suzuki K, Oka H, Morimoto M, Takata T, Isomoto H, Shiota G.
    Clin Exp Pharmacol Physiol; 2020 Jun 13; 47(6):940-946. PubMed ID: 32012313
    [Abstract] [Full Text] [Related]

  • 17. Smad7 is a TGF-beta-inducible attenuator of Smad2/3-mediated inhibition of embryonic lung morphogenesis.
    Zhao J, Crowe DL, Castillo C, Wuenschell C, Chai Y, Warburton D.
    Mech Dev; 2000 May 13; 93(1-2):71-81. PubMed ID: 10781941
    [Abstract] [Full Text] [Related]

  • 18. A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition.
    Yang J, Dai C, Liu Y.
    J Am Soc Nephrol; 2005 Jan 13; 16(1):68-78. PubMed ID: 15537870
    [Abstract] [Full Text] [Related]

  • 19. Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro.
    Fan JM, Ng YY, Hill PA, Nikolic-Paterson DJ, Mu W, Atkins RC, Lan HY.
    Kidney Int; 1999 Oct 13; 56(4):1455-67. PubMed ID: 10504497
    [Abstract] [Full Text] [Related]

  • 20. Beta-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cells are dependent on TGF-beta and Smad3.
    Guh JY, Chuang TD, Chen HC, Hung WC, Lai YH, Shin SJ, Chuang LY.
    Kidney Int; 2003 Dec 13; 64(6):2041-51. PubMed ID: 14633126
    [Abstract] [Full Text] [Related]

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