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258 related items for PubMed ID: 12049478

  • 1. The desferrithiocin (DFT) class of iron chelators: potential as antineoplastic agents.
    Kicic A, Chua AC, Baker E.
    Anticancer Drug Des; 2001; 16(4-5):195-207. PubMed ID: 12049478
    [Abstract] [Full Text] [Related]

  • 2. Desferrithiocin is a more potent antineoplastic agent than desferrioxamine.
    Kicic A, Chua AC, Baker E.
    Br J Pharmacol; 2002 Mar; 135(6):1393-402. PubMed ID: 11906952
    [Abstract] [Full Text] [Related]

  • 3. Development of tridentate iron chelators: from desferrithiocin to ICL670.
    Nick H, Acklin P, Lattmann R, Buehlmayer P, Hauffe S, Schupp J, Alberti D.
    Curr Med Chem; 2003 Jun; 10(12):1065-76. PubMed ID: 12678677
    [Abstract] [Full Text] [Related]

  • 4. Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.
    Chaston TB, Lovejoy DB, Watts RN, Richardson DR.
    Clin Cancer Res; 2003 Jan; 9(1):402-14. PubMed ID: 12538494
    [Abstract] [Full Text] [Related]

  • 5. Effect of iron chelators on proliferation and iron uptake in hepatoma cells.
    Kicic A, Chua AC, Baker E.
    Cancer; 2001 Dec 15; 92(12):3093-110. PubMed ID: 11753989
    [Abstract] [Full Text] [Related]

  • 6. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone.
    Richardson DR, Milnes K.
    Blood; 1997 Apr 15; 89(8):3025-38. PubMed ID: 9108424
    [Abstract] [Full Text] [Related]

  • 7. Substituent effects on desferrithiocin and desferrithiocin analogue iron-clearing and toxicity profiles.
    Bergeron RJ, Wiegand J, Bharti N, McManis JS.
    J Med Chem; 2012 Aug 23; 55(16):7090-103. PubMed ID: 22889170
    [Abstract] [Full Text] [Related]

  • 8. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents III: the effect of the ligands on molecular targets involved in proliferation.
    Darnell G, Richardson DR.
    Blood; 1999 Jul 15; 94(2):781-92. PubMed ID: 10397746
    [Abstract] [Full Text] [Related]

  • 9. Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells.
    Chua AC, Ingram HA, Raymond KN, Baker E.
    Eur J Biochem; 2003 Apr 15; 270(8):1689-98. PubMed ID: 12694182
    [Abstract] [Full Text] [Related]

  • 10. Iron chelators: in vitro inhibitory effect on the liver stage of rodent and human malaria.
    Stahel E, Mazier D, Guillouzo A, Miltgen F, Landau I, Mellouk S, Beaudoin RL, Langlois P, Gentilini M.
    Am J Trop Med Hyg; 1988 Sep 15; 39(3):236-40. PubMed ID: 3052118
    [Abstract] [Full Text] [Related]

  • 11. Structure-activity relationships among desazadesferrithiocin analogues.
    Bergeron RJ, Wiegand J, McManis JS, Weimar WR, Huang G.
    Adv Exp Med Biol; 2002 Sep 15; 509():167-84. PubMed ID: 12572994
    [Abstract] [Full Text] [Related]

  • 12. Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: novel iron chelators with selective antiproliferative action.
    Macková E, Hrušková K, Bendová P, Vávrová A, Jansová H, Hašková P, Kovaříková P, Vávrová K, Simůnek T.
    Chem Biol Interact; 2012 May 30; 197(2-3):69-79. PubMed ID: 22521999
    [Abstract] [Full Text] [Related]

  • 13. The impact of polyether chain length on the iron clearing efficiency and physiochemical properties of desferrithiocin analogues.
    Bergeron RJ, Bharti N, Wiegand J, McManis JS, Singh S, Abboud KA.
    J Med Chem; 2010 Apr 08; 53(7):2843-53. PubMed ID: 20232803
    [Abstract] [Full Text] [Related]

  • 14. The desferrithiocin pharmacophore.
    Bergeron RJ, Liu CZ, McManis JS, Xia MX, Algee SE, Wiegand J.
    J Med Chem; 1994 May 13; 37(10):1411-7. PubMed ID: 8182699
    [Abstract] [Full Text] [Related]

  • 15. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents.
    Richardson DR, Tran EH, Ponka P.
    Blood; 1995 Dec 01; 86(11):4295-306. PubMed ID: 7492790
    [Abstract] [Full Text] [Related]

  • 16. Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study.
    Gaboriau F, Chantrel-Groussard K, Rakba N, Loyer P, Pasdeloup N, Hider RC, Brissot P, Lescoat G.
    Biochem Pharmacol; 2004 Apr 15; 67(8):1479-87. PubMed ID: 15041465
    [Abstract] [Full Text] [Related]

  • 17. Effects of desferrithiocin and its derivatives on peripheral iron and striatal dopamine and 5-hydroxytryptamine metabolism in the ferrocene-loaded rat.
    Dexter DT, Ward RJ, Florence A, Jenner P, Crichton RR.
    Biochem Pharmacol; 1999 Jul 01; 58(1):151-5. PubMed ID: 10403528
    [Abstract] [Full Text] [Related]

  • 18. Desazadesmethyldesferrithiocin analogues as orally effective iron chelators.
    Bergeron RJ, Wiegand J, Weimar WR, Vinson JR, Bussenius J, Yao GW, McManis JS.
    J Med Chem; 1999 Jan 14; 42(1):95-108. PubMed ID: 9888836
    [Abstract] [Full Text] [Related]

  • 19. Desferrithiocin and desferrioxamine B. Cellular pharmacology and storage iron mobilization.
    Jin Y, Baquet A, Florence A, Crichton RR, Schneider YJ.
    Biochem Pharmacol; 1989 Oct 01; 38(19):3233-40. PubMed ID: 2818622
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of desferrithiocin and its synthetic analogues as orally effective iron chelators.
    Bergeron RJ, Wiegand J, Dionis JB, Egli-Karmakka M, Frei J, Huxley-Tencer A, Peter HH.
    J Med Chem; 1991 Jul 01; 34(7):2072-8. PubMed ID: 2066978
    [Abstract] [Full Text] [Related]

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