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Journal Abstract Search


669 related items for PubMed ID: 12050367

  • 1. Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment).
    Joshi P, Prasad VR.
    J Virol; 2002 Jul; 76(13):6545-57. PubMed ID: 12050367
    [Abstract] [Full Text] [Related]

  • 2. RNA-protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers.
    Lange MJ, Nguyen PDM, Callaway MK, Johnson MC, Burke DH.
    Nucleic Acids Res; 2017 Jun 02; 45(10):6087-6097. PubMed ID: 28334941
    [Abstract] [Full Text] [Related]

  • 3. Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication.
    Fisher TS, Joshi P, Prasad VR.
    J Virol; 2002 Apr 02; 76(8):4068-72. PubMed ID: 11907245
    [Abstract] [Full Text] [Related]

  • 4. Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase.
    Burke DH, Scates L, Andrews K, Gold L.
    J Mol Biol; 1996 Dec 13; 264(4):650-66. PubMed ID: 8980676
    [Abstract] [Full Text] [Related]

  • 5. Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides.
    Andreola ML, Calmels C, Michel J, Toulmé JJ, Litvak S.
    Eur J Biochem; 2000 Aug 13; 267(16):5032-40. PubMed ID: 10931185
    [Abstract] [Full Text] [Related]

  • 6. Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication.
    Joshi PJ, North TW, Prasad VR.
    Mol Ther; 2005 May 13; 11(5):677-86. PubMed ID: 15851006
    [Abstract] [Full Text] [Related]

  • 7. High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase.
    Ditzler MA, Lange MJ, Bose D, Bottoms CA, Virkler KF, Sawyer AW, Whatley AS, Spollen W, Givan SA, Burke DH.
    Nucleic Acids Res; 2013 Feb 01; 41(3):1873-84. PubMed ID: 23241386
    [Abstract] [Full Text] [Related]

  • 8. Novel aptamer inhibitors of human immunodeficiency virus reverse transcriptase.
    DeStefano JJ, Nair GR.
    Oligonucleotides; 2008 Jun 01; 18(2):133-44. PubMed ID: 18637731
    [Abstract] [Full Text] [Related]

  • 9. Combinatorial selection, inhibition, and antiviral activity of DNA thioaptamers targeting the RNase H domain of HIV-1 reverse transcriptase.
    Somasunderam A, Ferguson MR, Rojo DR, Thiviyanathan V, Li X, O'Brien WA, Gorenstein DG.
    Biochemistry; 2005 Aug 02; 44(30):10388-95. PubMed ID: 16042416
    [Abstract] [Full Text] [Related]

  • 10. DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity.
    Andreola ML, Pileur F, Calmels C, Ventura M, Tarrago-Litvak L, Toulmé JJ, Litvak S.
    Biochemistry; 2001 Aug 28; 40(34):10087-94. PubMed ID: 11513587
    [Abstract] [Full Text] [Related]

  • 11. Virion encapsidation of tRNA(3Lys)-ribozyme chimeric RNAs inhibits HIV infection.
    Westaway SK, Cagnon L, Chang Z, Li S, Li H, Larson GP, Zaia JA, Rossi JJ.
    Antisense Nucleic Acid Drug Dev; 1998 Jun 28; 8(3):185-97. PubMed ID: 9669656
    [Abstract] [Full Text] [Related]

  • 12. Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
    Boyer PL, Smith SJ, Zhao XZ, Das K, Gruber K, Arnold E, Burke TR, Hughes SH.
    J Virol; 2018 Jul 01; 92(13):. PubMed ID: 29643235
    [Abstract] [Full Text] [Related]

  • 13. Phosphorothioate oligonucleotides derived from human immunodeficiency virus type 1 (HIV-1) primer tRNALys3 are strong inhibitors of HIV-1 reverse transcriptase and arrest viral replication in infected cells.
    El Dirani-Diab R, Sarih-Cottin L, Delord B, Dumon B, Moreau S, Toulme JJ, Fleury H, Litvak S.
    Antimicrob Agents Chemother; 1997 Oct 01; 41(10):2141-8. PubMed ID: 9333039
    [Abstract] [Full Text] [Related]

  • 14. Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1.
    Chaloin L, Lehmann MJ, Sczakiel G, Restle T.
    Nucleic Acids Res; 2002 Sep 15; 30(18):4001-8. PubMed ID: 12235384
    [Abstract] [Full Text] [Related]

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  • 16. Effect of nucleoside analogs and non-nucleoside inhibitors of HIV-1 reverse transcriptase on cell-free virions.
    Ventura M, Tarrago-Litvak L, Dollé V, Nguyen CH, Legraverend M, Fleury HJ, Litvak S.
    Arch Virol; 1999 Sep 15; 144(3):513-23. PubMed ID: 10226617
    [Abstract] [Full Text] [Related]

  • 17. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
    Gao HQ, Boyer PL, Sarafianos SG, Arnold E, Hughes SH.
    J Mol Biol; 2000 Jul 07; 300(2):403-18. PubMed ID: 10873473
    [Abstract] [Full Text] [Related]

  • 18. PMTI, a broadly active unusual single-stranded polyribonucleotide, inhibits human immunodeficiency virus replication by multiple mechanisms.
    Buckheit RW, Lackman-Smith C, Snow MJ, Halliday SM, White EL, Ross LJ, Agrawal VK, Broom AD.
    Antivir Chem Chemother; 1999 Jan 07; 10(1):23-32. PubMed ID: 10079876
    [Abstract] [Full Text] [Related]

  • 19. New alkenyldiarylmethanes with enhanced potencies as anti-HIV agents which act as non-nucleoside reverse transcriptase inhibitors.
    Cushman M, Casimiro-Garcia A, Hejchman E, Ruell JA, Huang M, Schaeffer CA, Williamson K, Rice WG, Buckheit RW.
    J Med Chem; 1998 Jun 04; 41(12):2076-89. PubMed ID: 9622549
    [Abstract] [Full Text] [Related]

  • 20. Oxazole-Benzenesulfonamide Derivatives Inhibit HIV-1 Reverse Transcriptase Interaction with Cellular eEF1A and Reduce Viral Replication.
    Rawle DJ, Li D, Wu Z, Wang L, Choong M, Lor M, Reid RC, Fairlie DP, Harris J, Tachedjian G, Poulsen SA, Harrich D.
    J Virol; 2019 Jun 15; 93(12):. PubMed ID: 30918071
    [Abstract] [Full Text] [Related]


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