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308 related items for PubMed ID: 12051749

  • 1. CXCL8((3-73))K11R/G31P antagonizes ligand binding to the neutrophil CXCR1 and CXCR2 receptors and cellular responses to CXCL8/IL-8.
    Li F, Zhang X, Gordon JR.
    Biochem Biophys Res Commun; 2002 May 10; 293(3):939-44. PubMed ID: 12051749
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  • 3. Humanized forms of the CXCR1/CXCR2 antagonist, bovine CXCL8((3-74))K11R/G31P, effectively block ELR-CXC chemokine activity and airway endotoxemia pathology.
    Zhao X, Li F, Town JR, Zhang X, Wang W, Gordon JR.
    Int Immunopharmacol; 2007 Dec 15; 7(13):1723-31. PubMed ID: 17996682
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  • 6. ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels.
    Zhao X, Town JR, Li F, Zhang X, Cockcroft DW, Gordon JR.
    J Immunol; 2009 Mar 01; 182(5):3213-22. PubMed ID: 19234219
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  • 8. Effects of K11R and G31P Mutations on the Structure and Biological Activities of CXCL8: Solution Structure of Human CXCL8(3-72)K11R/G31P.
    Cheng HT, Yu HY, Gordon JR, Li F, Cheng JW.
    Molecules; 2017 Jul 21; 22(7):. PubMed ID: 28754019
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  • 9. CXCR1/CXCR2 antagonist G31P inhibits nephritis in a mouse model of uric acid nephropathy.
    Ye Y, Zhang Y, Wang B, Walana W, Wei J, Gordon JR, Li F.
    Biomed Pharmacother; 2018 Nov 21; 107():1142-1150. PubMed ID: 30257327
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  • 10. G31P, an antagonist against CXC chemokine receptors 1 and 2, inhibits growth of human prostate cancer cells in nude mice.
    Liu X, Peng J, Sun W, Yang S, Deng G, Li F, Cheng JW, Gordon JR.
    Tohoku J Exp Med; 2012 Oct 21; 228(2):147-56. PubMed ID: 23019013
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  • 11. The antagonist of CXCR1 and CXCR2 protects db/db mice from metabolic diseases through modulating inflammation.
    Cui S, Qiao L, Yu S, Men L, Li Y, Li F, Du J.
    Am J Physiol Endocrinol Metab; 2019 Dec 01; 317(6):E1205-E1217. PubMed ID: 31573846
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  • 12. Rabbit neutrophil chemotactic protein (NCP) activates both CXCR1 and CXCR2 and is the functional homologue for human CXCL6.
    Catusse J, Struyf S, Wuyts A, Weyler M, Loos T, Gijsbers K, Gouwy M, Proost P, Van Damme J.
    Biochem Pharmacol; 2004 Nov 15; 68(10):1947-55. PubMed ID: 15476666
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  • 14. CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks lung inflammation in swine barn dust-instilled mice.
    Schneberger D, Gordon JR, DeVasure JM, Boten JA, Heires AJ, Romberger DJ, Wyatt TA.
    Pulm Pharmacol Ther; 2015 Apr 15; 31():55-62. PubMed ID: 25681618
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  • 15. The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases.
    Russo RC, Garcia CC, Teixeira MM, Amaral FA.
    Expert Rev Clin Immunol; 2014 May 15; 10(5):593-619. PubMed ID: 24678812
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  • 16. Porcine CXCR1/2 antagonist CXCL8(3-72)G31P inhibits lung inflammation in LPS-challenged mice.
    Wang X, Li Y, Li L, Jiao Z, Liu X, Cheng G, Gu C, Hu X, Zhang W.
    Sci Rep; 2020 Jan 27; 10(1):1210. PubMed ID: 31988368
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