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435 related items for PubMed ID: 12052830

  • 1. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells.
    Guha M, Mackman N.
    J Biol Chem; 2002 Aug 30; 277(35):32124-32. PubMed ID: 12052830
    [Abstract] [Full Text] [Related]

  • 2. Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression.
    Guha M, O'Connell MA, Pawlinski R, Hollis A, McGovern P, Yan SF, Stern D, Mackman N.
    Blood; 2001 Sep 01; 98(5):1429-39. PubMed ID: 11520792
    [Abstract] [Full Text] [Related]

  • 3. Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA.
    Giri RK, Selvaraj SK, Kalra VK.
    J Immunol; 2003 May 15; 170(10):5281-94. PubMed ID: 12734378
    [Abstract] [Full Text] [Related]

  • 4. Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages.
    Luyendyk JP, Schabbauer GA, Tencati M, Holscher T, Pawlinski R, Mackman N.
    J Immunol; 2008 Mar 15; 180(6):4218-26. PubMed ID: 18322234
    [Abstract] [Full Text] [Related]

  • 5. Regulation of the tissue factor gene in human monocytic cells. Role of AP-1, NF-kappa B/Rel, and Sp1 proteins in uninduced and lipopolysaccharide-induced expression.
    Oeth P, Parry GC, Mackman N.
    Arterioscler Thromb Vasc Biol; 1997 Feb 15; 17(2):365-74. PubMed ID: 9081693
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  • 7. Protease inhibitors block lipopolysaccharide induction of tissue factor gene expression in human monocytic cells by preventing activation of c-Rel/p65 heterodimers.
    Mackman N.
    J Biol Chem; 1994 Oct 21; 269(42):26363-7. PubMed ID: 7929355
    [Abstract] [Full Text] [Related]

  • 8. Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide.
    Martin M, Schifferle RE, Cuesta N, Vogel SN, Katz J, Michalek SM.
    J Immunol; 2003 Jul 15; 171(2):717-25. PubMed ID: 12847238
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  • 11. Differential regulation of CD44 expression by lipopolysaccharide (LPS) and TNF-alpha in human monocytic cells: distinct involvement of c-Jun N-terminal kinase in LPS-induced CD44 expression.
    Gee K, Lim W, Ma W, Nandan D, Diaz-Mitoma F, Kozlowski M, Kumar A.
    J Immunol; 2002 Nov 15; 169(10):5660-72. PubMed ID: 12421945
    [Abstract] [Full Text] [Related]

  • 12. Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors.
    Yao J, Mackman N, Edgington TS, Fan ST.
    J Biol Chem; 1997 Jul 11; 272(28):17795-801. PubMed ID: 9211933
    [Abstract] [Full Text] [Related]

  • 13. The rLrp of Mycobacterium tuberculosis inhibits proinflammatory cytokine production and downregulates APC function in mouse macrophages via a TLR2-mediated PI3K/Akt pathway activation-dependent mechanism.
    Liu Y, Li JY, Chen ST, Huang HR, Cai H.
    Cell Mol Immunol; 2016 Nov 11; 13(6):729-746. PubMed ID: 26166760
    [Abstract] [Full Text] [Related]

  • 14. PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.
    Schabbauer G, Tencati M, Pedersen B, Pawlinski R, Mackman N.
    Arterioscler Thromb Vasc Biol; 2004 Oct 11; 24(10):1963-9. PubMed ID: 15319270
    [Abstract] [Full Text] [Related]

  • 15. Production of matrix metalloproteinase-9 by activated human monocytes involves a phosphatidylinositol-3 kinase/Akt/IKKalpha/NF-kappaB pathway.
    Lu Y, Wahl LM.
    J Leukoc Biol; 2005 Jul 11; 78(1):259-65. PubMed ID: 15800029
    [Abstract] [Full Text] [Related]

  • 16. L6 myoblast differentiation is modulated by Cdk5 via the PI3K-AKT-p70S6K signaling pathway.
    Sarker KP, Lee KY.
    Oncogene; 2004 Aug 12; 23(36):6064-70. PubMed ID: 15208659
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  • 17. TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase-AKT-JNK pathway.
    Funakoshi-Tago M, Tago K, Sonoda Y, Tominaga S, Kasahara T.
    Eur J Biochem; 2003 Mar 12; 270(6):1257-68. PubMed ID: 12631284
    [Abstract] [Full Text] [Related]

  • 18. IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide.
    Yang F, Tang E, Guan K, Wang CY.
    J Immunol; 2003 Jun 01; 170(11):5630-5. PubMed ID: 12759443
    [Abstract] [Full Text] [Related]

  • 19. Specificity, diversity, and convergence in VEGF and TNF-alpha signaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells.
    Mechtcheriakova D, Schabbauer G, Lucerna M, Clauss M, De Martin R, Binder BR, Hofer E.
    FASEB J; 2001 Jan 01; 15(1):230-242. PubMed ID: 11149911
    [Abstract] [Full Text] [Related]

  • 20. Differential involvement of phosphoinositide 3-kinase/Akt in human RPE MCP-1 and IL-8 expression.
    Bian ZM, Elner SG, Yoshida A, Elner VM.
    Invest Ophthalmol Vis Sci; 2004 Jun 01; 45(6):1887-96. PubMed ID: 15161854
    [Abstract] [Full Text] [Related]

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