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334 related items for PubMed ID: 12054576

  • 1. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response.
    Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.
    Biochem Biophys Res Commun; 2002 Apr 26; 293(1):145-9. PubMed ID: 12054576
    [Abstract] [Full Text] [Related]

  • 2. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.
    Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191
    [Abstract] [Full Text] [Related]

  • 3. Lipopolysaccharide and cecal ligation/puncture differentially affect the subcellular distribution of the pregnane X receptor but consistently cause suppression of its target genes CYP3A.
    Sachdeva K, Yan B, Chichester CO.
    Shock; 2003 May 01; 19(5):469-74. PubMed ID: 12744492
    [Abstract] [Full Text] [Related]

  • 4. Perinatal lipopolysaccharide exposure downregulates pregnane X receptor and Cyp3a11 expression in fetal mouse liver.
    Xu DX, Chen YH, Wang JP, Sun MF, Wang H, Wei LZ, Wei W.
    Toxicol Sci; 2005 Sep 01; 87(1):38-45. PubMed ID: 15976188
    [Abstract] [Full Text] [Related]

  • 5. Melatonin attenuates lipopolysaccharide-induced down-regulation of pregnane X receptor and its target gene CYP3A in mouse liver.
    Xu DX, Wei W, Sun MF, Wei LZ, Wang JP.
    J Pineal Res; 2005 Jan 01; 38(1):27-34. PubMed ID: 15617534
    [Abstract] [Full Text] [Related]

  • 6. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
    Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW.
    Pharmacogenomics J; 2004 Jan 01; 4(2):91-101. PubMed ID: 14770174
    [Abstract] [Full Text] [Related]

  • 7. Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C.
    Ding X, Staudinger JL.
    Biochem Pharmacol; 2005 Mar 01; 69(5):867-73. PubMed ID: 15710363
    [Abstract] [Full Text] [Related]

  • 8. Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression.
    Vyhlidal CA, Gaedigk R, Leeder JS.
    Drug Metab Dispos; 2006 Jan 01; 34(1):131-7. PubMed ID: 16243958
    [Abstract] [Full Text] [Related]

  • 9. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
    Wyde ME, Bartolucci E, Ueda A, Zhang H, Yan B, Negishi M, You L.
    Mol Pharmacol; 2003 Aug 01; 64(2):474-81. PubMed ID: 12869653
    [Abstract] [Full Text] [Related]

  • 10. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
    Teng S, Piquette-Miller M.
    J Pharmacol Exp Ther; 2005 Feb 01; 312(2):841-8. PubMed ID: 15456840
    [Abstract] [Full Text] [Related]

  • 11. Humanized xenobiotic response in mice expressing nuclear receptor SXR.
    Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM.
    Nature; 2000 Jul 27; 406(6794):435-9. PubMed ID: 10935643
    [Abstract] [Full Text] [Related]

  • 12. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
    Zhang H, LeCulyse E, Liu L, Hu M, Matoney L, Zhu W, Yan B.
    Arch Biochem Biophys; 1999 Aug 01; 368(1):14-22. PubMed ID: 10415106
    [Abstract] [Full Text] [Related]

  • 13. Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response.
    Kim MS, Shigenaga J, Moser A, Grunfeld C, Feingold KR.
    Am J Physiol Endocrinol Metab; 2004 Oct 01; 287(4):E731-8. PubMed ID: 15198932
    [Abstract] [Full Text] [Related]

  • 14. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
    Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW.
    Drug Metab Dispos; 2007 Jan 01; 35(1):36-42. PubMed ID: 17020958
    [Abstract] [Full Text] [Related]

  • 15. Chronic ethanol exposure downregulates hepatic expression of pregnane X receptor and P450 3A11 in female ICR mice.
    Wang JP, Xu DX, Sun MF, Chen YH, Wang H, Wei W.
    Toxicology; 2005 Nov 15; 215(3):234-44. PubMed ID: 16126318
    [Abstract] [Full Text] [Related]

  • 16. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
    Staudinger J, Liu Y, Madan A, Habeebu S, Klaassen CD.
    Drug Metab Dispos; 2001 Nov 15; 29(11):1467-72. PubMed ID: 11602523
    [Abstract] [Full Text] [Related]

  • 17. Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice.
    Richardson TA, Morgan ET.
    J Pharmacol Exp Ther; 2005 Aug 15; 314(2):703-9. PubMed ID: 15860574
    [Abstract] [Full Text] [Related]

  • 18. Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.
    Slatter JG, Cheng O, Cornwell PD, de Souza A, Rockett J, Rushmore T, Hartley D, Evers R, He Y, Dai X, Hu R, Caguyong M, Roberts CJ, Castle J, Ulrich RG.
    Xenobiotica; 2006 Aug 15; 36(10-11):902-37. PubMed ID: 17118914
    [Abstract] [Full Text] [Related]

  • 19. CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.
    Chirulli V, Longo V, Marini S, Mazzaccaro A, Fiorio R, Gervasi PG.
    Life Sci; 2005 Apr 15; 76(22):2535-46. PubMed ID: 15769478
    [Abstract] [Full Text] [Related]

  • 20. Ligand dependent hepatic gene expression profiles of nuclear receptors CAR and PXR.
    Tojima H, Kakizaki S, Yamazaki Y, Takizawa D, Horiguchi N, Sato K, Mori M.
    Toxicol Lett; 2012 Aug 03; 212(3):288-97. PubMed ID: 22698814
    [Abstract] [Full Text] [Related]

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