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216 related items for PubMed ID: 12058075

  • 1. Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.
    Lock LS, Maroun CR, Naujokas MA, Park M.
    Mol Biol Cell; 2002 Jun; 13(6):2132-46. PubMed ID: 12058075
    [Abstract] [Full Text] [Related]

  • 2. Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases.
    Lock LS, Royal I, Naujokas MA, Park M.
    J Biol Chem; 2000 Oct 06; 275(40):31536-45. PubMed ID: 10913131
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  • 3. Gab2 requires membrane targeting and the Met binding motif to promote lamellipodia, cell scatter, and epithelial morphogenesis downstream from the Met receptor.
    Frigault MM, Naujokas MA, Park M.
    J Cell Physiol; 2008 Mar 06; 214(3):694-705. PubMed ID: 17894413
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  • 4. Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain.
    Lock LS, Frigault MM, Saucier C, Park M.
    J Biol Chem; 2003 Aug 08; 278(32):30083-90. PubMed ID: 12766170
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  • 5. The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair.
    Fan S, Ma YX, Gao M, Yuan RQ, Meng Q, Goldberg ID, Rosen EM.
    Mol Cell Biol; 2001 Aug 08; 21(15):4968-84. PubMed ID: 11438654
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  • 6. Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
    Schaeper U, Gehring NH, Fuchs KP, Sachs M, Kempkes B, Birchmeier W.
    J Cell Biol; 2000 Jun 26; 149(7):1419-32. PubMed ID: 10871282
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  • 9. Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
    Weidner KM, Di Cesare S, Sachs M, Brinkmann V, Behrens J, Birchmeier W.
    Nature; 1996 Nov 14; 384(6605):173-6. PubMed ID: 8906793
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  • 11. A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis.
    Maroun CR, Moscatello DK, Naujokas MA, Holgado-Madruga M, Wong AJ, Park M.
    J Biol Chem; 1999 Oct 29; 274(44):31719-26. PubMed ID: 10531383
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  • 12. Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells.
    Caron C, Spring K, Laramée M, Chabot C, Cloutier M, Gu H, Royal I.
    Cell Signal; 2009 Jun 29; 21(6):943-53. PubMed ID: 19233262
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  • 13. Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1.
    Zhao C, Yu DH, Shen R, Feng GS.
    J Biol Chem; 1999 Jul 09; 274(28):19649-54. PubMed ID: 10391903
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  • 14. Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.
    Bardelli A, Longati P, Gramaglia D, Stella MC, Comoglio PM.
    Oncogene; 1997 Dec 18; 15(25):3103-11. PubMed ID: 9444958
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  • 16. Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.
    Nguyen L, Holgado-Madruga M, Maroun C, Fixman ED, Kamikura D, Fournier T, Charest A, Tremblay ML, Wong AJ, Park M.
    J Biol Chem; 1997 Aug 15; 272(33):20811-9. PubMed ID: 9252406
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  • 17. Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor.
    Meng S, Chen Z, Munoz-Antonia T, Wu J.
    Biochem J; 2005 Oct 01; 391(Pt 1):143-51. PubMed ID: 15952937
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  • 18. The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
    Lewitzky M, Kardinal C, Gehring NH, Schmidt EK, Konkol B, Eulitz M, Birchmeier W, Schaeper U, Feller SM.
    Oncogene; 2001 Mar 01; 20(9):1052-62. PubMed ID: 11314042
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  • 19. The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering.
    Tulasne D, Paumelle R, Weidner KM, Vandenbunder B, Fafeur V.
    Mol Biol Cell; 1999 Mar 01; 10(3):551-65. PubMed ID: 10069803
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  • 20. Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
    Schaeper U, Vogel R, Chmielowiec J, Huelsken J, Rosario M, Birchmeier W.
    Proc Natl Acad Sci U S A; 2007 Sep 25; 104(39):15376-81. PubMed ID: 17881575
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