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249 related items for PubMed ID: 12062389

  • 1. Establishment and use of a cell line expressing HSV-1 thymidine kinase to characterize viral thymidine kinase-dependent drug-resistance.
    Kim JH, Park JB, Bae PK, Kim HS, Kim DW, Ahn JK, Lee CK.
    Antiviral Res; 2002 Jun; 54(3):163-74. PubMed ID: 12062389
    [Abstract] [Full Text] [Related]

  • 2. Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene.
    Yang L, Hwang R, Chiang Y, Gordon EM, Anderson WF, Parekh D.
    Clin Cancer Res; 1998 Mar; 4(3):731-41. PubMed ID: 9533543
    [Abstract] [Full Text] [Related]

  • 3. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2.
    Balzarini J, Bohman C, De Clercq E.
    J Biol Chem; 1993 Mar 25; 268(9):6332-7. PubMed ID: 8384209
    [Abstract] [Full Text] [Related]

  • 4. [Hypoxia responsive element regulated herpes simplex virus-thymidine kinase system enhances killing effect of gancyclovir on Ewing's sarcoma cell line under hypoxic condition].
    Si YJ, Guang LX, Yuan FH, Zhang KB.
    Zhonghua Er Ke Za Zhi; 2006 Aug 25; 44(8):616-20. PubMed ID: 17083794
    [Abstract] [Full Text] [Related]

  • 5. Genotypic and phenotypic characterization of the thymidine kinase of ACV-resistant HSV-1 derived from an acyclovir-sensitive herpes simplex virus type 1 strain.
    Saijo M, Suzutani T, De Clercq E, Niikura M, Maeda A, Morikawa S, Kurane I.
    Antiviral Res; 2002 Dec 25; 56(3):253-62. PubMed ID: 12406508
    [Abstract] [Full Text] [Related]

  • 6. Herpes simplex virus thymidine kinase activity of thymidine kinase-deficient Escherichia coli K-12 mutant transformed by hybrid plasmids.
    Kit S, Otsuka H, Qavi H, Hazen M.
    Proc Natl Acad Sci U S A; 1981 Jan 25; 78(1):582-6. PubMed ID: 6264449
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  • 7. Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1.
    Bae PK, Kim JH, Kim HS, Chung IK, Paik SG, Lee CK.
    Antiviral Res; 2006 Jul 25; 70(3):93-104. PubMed ID: 16546268
    [Abstract] [Full Text] [Related]

  • 8. Monitoring of bystander effect of herpes simplex virus thymidine kinase/acyclovir system using fluorescence resonance energy transfer technique.
    Xiong T, Li Y, Ni F, Zhang F.
    J Biomed Nanotechnol; 2012 Feb 25; 8(1):74-9. PubMed ID: 22515095
    [Abstract] [Full Text] [Related]

  • 9. Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.
    Coen DM, Irmiere AF, Jacobson JG, Kerns KM.
    Virology; 1989 Feb 25; 168(2):221-31. PubMed ID: 2536980
    [Abstract] [Full Text] [Related]

  • 10. [Effects of herpes simplex virus thymidine kinase gene transduction and prodrug on ovarian cancer cell].
    Liang Z, Kuang J, Lin Z.
    Zhonghua Fu Chan Ke Za Zhi; 1997 Aug 25; 32(8):467-70. PubMed ID: 9639739
    [Abstract] [Full Text] [Related]

  • 11. Selection of HSV-1 TK gene-transfected murine mammary carcinoma cells resistant to (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and ganciclovir (GCV).
    Degrève B, De Clercq E, Balzarini J.
    Gene Ther; 2000 Sep 25; 7(18):1543-52. PubMed ID: 11021592
    [Abstract] [Full Text] [Related]

  • 12. (E)-5-(2-bromovinyl)-2'-deoxyuridine potentiates ganciclovir-mediated cytotoxicity on herpes simplex virus-thymidine kinase--expressing cells.
    Hamel W, Zirkel D, Mehdorn HM, Westphal M, Israel MA.
    Cancer Gene Ther; 2001 May 25; 8(5):388-96. PubMed ID: 11477459
    [Abstract] [Full Text] [Related]

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  • 14. Reactivation of thymidine kinase-defective herpes simplex virus is enhanced by nucleoside.
    Tenser RB, Gaydos A, Hay KA.
    J Virol; 1996 Feb 25; 70(2):1271-6. PubMed ID: 8551594
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  • 16. Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance.
    Bennour E, Ferrand C, Rémy-Martin JP, Certoux JM, Gorke S, Qasim W, Gaspar HB, Baumert T, Duperrier A, Deschamps M, Fehse B, Tiberghien P, Robinet E.
    Hum Gene Ther; 2008 Jul 25; 19(7):699-709. PubMed ID: 18557699
    [Abstract] [Full Text] [Related]

  • 17. Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations.
    Duffy KE, Quail MR, Nguyen TT, Wittrock RJ, Bartus JO, Halsey WM, Leary JJ, Bacon TH, Sarisky RT.
    BMC Infect Dis; 2002 May 07; 2():7. PubMed ID: 12019036
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  • 20. Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs.
    Prichard MN, Williams AD, Keith KA, Harden EA, Kern ER.
    Antiviral Res; 2006 Aug 07; 71(1):1-6. PubMed ID: 16530858
    [Abstract] [Full Text] [Related]

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