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Journal Abstract Search

155 related items for PubMed ID: 12062933

  • 1. Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats.
    Li J, Kaneko T, Wang Y, Qin LQ, Wang PY, Sato A.
    Toxicology; 2002 Jul 01; 176(1-2):91-100. PubMed ID: 12062933
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  • 2. Role of CYP3A in ethanol-mediated increases in acetaminophen hepatotoxicity.
    Kostrubsky VE, Szakacs JG, Jeffery EH, Wood SG, Bement WJ, Wrighton SA, Sinclair PR, Sinclair JF.
    Toxicol Appl Pharmacol; 1997 Apr 01; 143(2):315-23. PubMed ID: 9144448
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  • 3. Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes.
    Sahi J, Hamilton G, Sinz M, Barros S, Huang SM, Lesko LJ, LeCluyse EL.
    Xenobiotica; 2000 Mar 01; 30(3):273-84. PubMed ID: 10752642
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  • 4. Effect of troglitazone on urinary excretion of 6beta-hydroxycortisol.
    Koup JR, Anderson GD, Loi CM.
    J Clin Pharmacol; 1998 Sep 01; 38(9):815-8. PubMed ID: 9753209
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  • 8. Enzyme-induction dependent bioactivation of troglitazone and troglitazone quinone in vivo.
    Tettey JN, Maggs JL, Rapeport WG, Pirmohamed M, Park BK.
    Chem Res Toxicol; 2001 Aug 01; 14(8):965-74. PubMed ID: 11511170
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  • 9. Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition.
    Sahi J, Black CB, Hamilton GA, Zheng X, Jolley S, Rose KA, Gilbert D, LeCluyse EL, Sinz MW.
    Drug Metab Dispos; 2003 Apr 01; 31(4):439-46. PubMed ID: 12642470
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  • 12. Metabolic effects of troglitazone in the Goto-Kakizaki rat, a non-obese and normolipidemic rodent model of non-insulin-dependent diabetes mellitus.
    O'Rourke CM, Davis JA, Saltiel AR, Cornicelli JA.
    Metabolism; 1997 Feb 01; 46(2):192-8. PubMed ID: 9030828
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  • 13. Retinol potentiates acetaminophen-induced hepatotoxicity in the mouse: mechanistic studies.
    Bray BJ, Rosengren RJ.
    Toxicol Appl Pharmacol; 2001 Jun 15; 173(3):129-36. PubMed ID: 11437634
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  • 14. Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes.
    Yamazaki H, Shibata A, Suzuki M, Nakajima M, Shimada N, Guengerich FP, Yokoi T.
    Drug Metab Dispos; 1999 Nov 15; 27(11):1260-6. PubMed ID: 10534310
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  • 16. In vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: comparison with pioglitazone and rosiglitazone.
    Yamazaki H, Suzuki M, Tane K, Shimada N, Nakajima M, Yokoi T.
    Xenobiotica; 2000 Jan 15; 30(1):61-70. PubMed ID: 10659951
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  • 17. 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2.
    Xu S, Liu J, Shi J, Wang Z, Ji L.
    Sci Rep; 2017 Nov 28; 7(1):16511. PubMed ID: 29184146
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  • 19. Biological reactive intermediates in drug discovery and development: a perspective from the pharmaceutical industry.
    Baillie TA, Kassahun K.
    Adv Exp Med Biol; 2001 Nov 28; 500():45-51. PubMed ID: 11764978
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  • 20. Zonation of acetaminophen metabolism and cytochrome P450 2E1-mediated toxicity studied in isolated periportal and perivenous hepatocytes.
    Anundi I, Lähteenmäki T, Rundgren M, Moldeus P, Lindros KO.
    Biochem Pharmacol; 1993 Mar 24; 45(6):1251-9. PubMed ID: 8466546
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